Myorg (myogenesis regulating glycosidase (putative)) - Rat Genome Database

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Gene: Myorg (myogenesis regulating glycosidase (putative)) Mus musculus
Analyze
Symbol: Myorg
Name: myogenesis regulating glycosidase (putative)
RGD ID: 1320365
MGI Page MGI
Description: Predicted to enable hydrolase activity, hydrolyzing O-glycosyl compounds. Acts upstream of or within positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of protein kinase B signaling; and skeletal muscle fiber development. Located in endoplasmic reticulum membrane and nuclear membrane. Is expressed in several structures, including alimentary system; brain; connective tissue; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in basal ganglia calcification. Orthologous to human MYORG (myogenesis regulating glycosidase (putative)); INTERACTS WITH 4-hydroxyphenyl retinamide; ethanol; tetrachloromethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA408153; AI4641; AI464131; AI604836; expressed sequence AI464131; full=Nuclear envelope transmembrane protein 37; Gm762; hypothetical protein LOC329828; Kiaa1161; MGC175917; myogenesis-regulating glycosidase; NET3; NET37; nuclear envelope transmembrane protein 37; RP23-100C7.2; uncharacterized family 31 glucosidase KIAA1161
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39441,495,601 - 41,503,132 (-)NCBIGRCm39mm39
GRCm39 Ensembl441,495,604 - 41,503,076 (-)Ensembl
GRCm38441,491,847 - 41,503,135 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl441,495,604 - 41,503,076 (-)EnsemblGRCm38mm10GRCm38
MGSCv37441,442,637 - 41,450,109 (-)NCBIGRCm37mm9NCBIm37
MGSCv36441,684,274 - 41,691,728 (-)NCBImm8
Celera441,156,888 - 41,164,370 (-)NCBICelera
Cytogenetic Map4A5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10922068   PMID:12466851   PMID:12477932   PMID:14610273   PMID:15368895   PMID:19706595   PMID:21267068   PMID:21362171   PMID:21677750   PMID:21873635   PMID:24194600  
PMID:27626380   PMID:29910000   PMID:32325033  


Genomics

Comparative Map Data
Myorg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39441,495,601 - 41,503,132 (-)NCBIGRCm39mm39
GRCm39 Ensembl441,495,604 - 41,503,076 (-)Ensembl
GRCm38441,491,847 - 41,503,135 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl441,495,604 - 41,503,076 (-)EnsemblGRCm38mm10GRCm38
MGSCv37441,442,637 - 41,450,109 (-)NCBIGRCm37mm9NCBIm37
MGSCv36441,684,274 - 41,691,728 (-)NCBImm8
Celera441,156,888 - 41,164,370 (-)NCBICelera
Cytogenetic Map4A5NCBI
MYORG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl934,366,666 - 34,376,898 (-)EnsemblGRCh38hg38GRCh38
GRCh38934,366,149 - 34,376,952 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37934,366,664 - 34,376,896 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36934,358,907 - 34,366,894 (-)NCBINCBI36hg18NCBI36
Celera934,300,413 - 34,308,399 (-)NCBI
Cytogenetic Map9p13.3NCBI
HuRef934,323,996 - 34,331,984 (-)NCBIHuRef
CHM1_1934,368,669 - 34,376,658 (-)NCBICHM1_1
Myorg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2556,654,257 - 56,664,467 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl557,876,498 - 57,881,944 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0557,873,404 - 57,882,008 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0562,402,424 - 62,409,832 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4558,917,805 - 58,923,251 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1558,917,973 - 58,920,155 (-)NCBI
Celera555,254,804 - 55,260,248 (-)NCBICelera
Cytogenetic Map5q22NCBI
Myorg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554721,735,292 - 1,740,304 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554721,735,292 - 1,740,304 (+)NCBIChiLan1.0ChiLan1.0
MYORG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1935,013,976 - 35,022,065 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl935,015,847 - 35,017,991 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0934,205,177 - 34,213,351 (-)NCBIMhudiblu_PPA_v0panPan3
MYORG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11151,070,088 - 51,077,595 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1151,071,707 - 51,073,851 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1149,699,649 - 49,707,145 (-)NCBI
ROS_Cfam_1.01152,012,064 - 52,019,568 (-)NCBI
UMICH_Zoey_3.11150,674,765 - 50,682,260 (-)NCBI
UNSW_CanFamBas_1.01150,542,862 - 50,550,362 (-)NCBI
UU_Cfam_GSD_1.01151,307,660 - 51,315,160 (-)NCBI
MYORG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1032,348,701 - 32,443,968 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11032,436,349 - 32,443,971 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MYORG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11246,235,327 - 46,243,153 (+)NCBI
ChlSab1.1 Ensembl1246,240,208 - 46,242,352 (+)Ensembl
Vero_WHO_p1.0NW_02366603843,352,599 - 43,360,841 (+)NCBI
Myorg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473638,775,648 - 38,786,112 (-)NCBI

Position Markers
AI464131  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38441,495,633 - 41,495,837UniSTSGRCm38
MGSCv37441,442,666 - 41,442,870UniSTSGRCm37
Celera441,156,917 - 41,157,121UniSTS
Cytogenetic Map4A5UniSTS
AI604836  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38441,495,644 - 41,495,789UniSTSGRCm38
MGSCv37441,442,677 - 41,442,822UniSTSGRCm37
Celera441,156,928 - 41,157,073UniSTS
Cytogenetic Map4A5UniSTS
Whitehead/MRC_RH4662.45UniSTS
RH124675  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38441,495,622 - 41,495,798UniSTSGRCm38
MGSCv37441,442,655 - 41,442,831UniSTSGRCm37
Celera441,156,906 - 41,157,082UniSTS
Cytogenetic Map4A5UniSTS
RH125773  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38441,495,621 - 41,495,870UniSTSGRCm38
MGSCv37441,442,654 - 41,442,903UniSTSGRCm37
Celera441,156,905 - 41,157,154UniSTS
Cytogenetic Map4A5UniSTS
Whitehead/MRC_RH4662.07UniSTS
UniSTS:234900  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38441,496,810 - 41,497,042UniSTSGRCm38
MGSCv37441,443,843 - 41,444,075UniSTSGRCm37
Celera441,158,102 - 41,158,334UniSTS
Cytogenetic Map4A5UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156183778Mouse
1302125Lxw1_mlupus BXSB x NZW 1 (mouse)Not determined4868324042683429Mouse
1302010Wta1_mweight adult 1 (mouse)Not determined4868324042683429Mouse
1558992Ses8_msalmonella enteritidis susceptibility 8 (mouse)Not determined4868324042683429Mouse
1301473Triglq1_mtriglyceride QTL 1 (mouse)Not determined4868324042683429Mouse
4141302Ssrq5_mstress response QTL 5 (mouse)Not determined868324042683430Mouse
10401905Sicd3_mseizure-induced cell death 3 (mouse)Not determined4939552543760862Mouse
10401115Pgia35_mproteoglycan induced arthritis 35 (mouse)Not determined41256237746562509Mouse
12880405Jcdq1_mjoint cartilage degeneration QTL 1 (mouse)41256237746562509Mouse
4142318Lyr2_mlymphoma resistance 2 (mouse)Not determined1401045763365441Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117215009Mouse
1301203Alcp8_malcohol preference locus 8 (mouse)Not determined41739516051395290Mouse
1301237Alcp7_malcohol preference locus 7 (mouse)Not determined41739516051395290Mouse
4141555Nbwa2_mNZB and NZW autoimmunity 2 (mouse)Not determined41789251551892635Mouse
4141911W6q15_mweight 6 weeks QTL 15 (mouse)Not determined1789261689063979Mouse
1357645Lvrq9_mliver weight QTL 9 (mouse)Not determined41789261689063979Mouse
1357453Kidq4_mkidney weight QTL 4 (mouse)Not determined41789261689063979Mouse
39128211Lwq22_mliver weight QTL 22 (mouse)41789261689063979Mouse
25440481Moaq1_mmodifier of alien QTL 1 (mouse)41950000046000000Mouse
1300769Pcyts2_mplasmacytoma susceptibility 2 (mouse)Not determined42211194456112145Mouse
1302058Hrtfm3_mheart failure modifier 3 (mouse)Not determined42211194456112145Mouse
1302075Bdln6_mbody length 6 (mouse)Not determined42237344856373612Mouse
1301437Scon1_msucrose consumption 1 (mouse)Not determined42237344856373612Mouse
1301697Sluc18_msusceptibility to lung cancer 18 (mouse)Not determined42237344856373612Mouse
1302184Aaom1_mautoimmune aoritis in MRL mice 1 (mouse)Not determined42432229946332776Mouse
1300574Im2_mimmunoregulatory 2 (mouse)Not determined42807768262077816Mouse
1301586Stheal3_msoft tissue heal 3 (mouse)Not determined42865844262658566Mouse
1357877Synch1_msynechia 1 (mouse)Not determined42870992562710107Mouse
1301990Arvm1_mautoimmune renal vasculitis 1 (mouse)Not determined42933264663332776Mouse
4142290Ssrq9_mstress response QTL 9 (mouse)Not determined3439516046332776Mouse
1301792Hdlq10_mHDL QTL 10 (mouse)Not determined43585970769859853Mouse
1300977Mopkd1_mmodifier of polycystic kidney disease progression 1 (mouse)Not determined43655083970550967Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000129100000Mouse
1302116Bbaa1_mB.burgdorferi-associated arthritis 1 (mouse)Not determined43825093072251078Mouse
10412178Habiir2_mhyperoxic acute lung injury imprinted region 2 (mouse)Not determined43945212663365441Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1052
Count of miRNA genes:592
Interacting mature miRNAs:726
Transcripts:ENSMUST00000054920, ENSMUST00000149596
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000054920   ⟹   ENSMUSP00000059038
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl441,495,604 - 41,503,076 (-)Ensembl
RefSeq Acc Id: ENSMUST00000149596   ⟹   ENSMUSP00000122357
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl441,499,494 - 41,502,668 (-)Ensembl
RefSeq Acc Id: NM_001085515   ⟹   NP_001078984
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39441,495,601 - 41,503,075 (-)NCBI
GRCm38441,495,601 - 41,503,075 (-)NCBI
MGSCv37441,442,637 - 41,450,109 (-)RGD
Celera441,156,885 - 41,164,369 (-)ENTREZGENE
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036164189   ⟹   XP_036020082
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39441,495,603 - 41,503,132 (-)NCBI
RefSeq Acc Id: XM_036164190   ⟹   XP_036020083
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39441,495,603 - 41,503,132 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001078984   ⟸   NM_001085515
- UniProtKB: Q69ZQ1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000059038   ⟸   ENSMUST00000054920
RefSeq Acc Id: ENSMUSP00000122357   ⟸   ENSMUST00000149596
RefSeq Acc Id: XP_036020083   ⟸   XM_036164190
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036020082   ⟸   XM_036164189
- Peptide Label: isoform X1

Promoters
RGD ID:6847777
Promoter ID:MM_ACW:34276
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Kidney,   Liver
Transcripts:AI464131.CSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36441,444,586 - 41,445,367 (-)MPROMDB
RGD ID:6834793
Promoter ID:MM_KWN:37160
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day3,   3T3L1_Day6,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_001085515,   OTTMUST00000015210
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36441,449,794 - 41,450,294 (-)MPROMDB
RGD ID:6883096
Promoter ID:EPDNEW_M4999
Type:initiation region
Name:AI464131_1
Description:Mus musculus expressed sequence AI464131 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38441,503,067 - 41,503,127EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2140300 AgrOrtholog
Ensembl Genes ENSMUSG00000046312 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000059038 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000122357 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000054920 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000149596 UniProtKB/TrEMBL
InterPro Glyco_hydro_31 UniProtKB/Swiss-Prot
  Glycoside_hydrolase_SF UniProtKB/Swiss-Prot
KEGG Report mmu:329828 UniProtKB/Swiss-Prot
MGD MGI:2140300 ENTREZGENE
NCBI Gene 329828 ENTREZGENE
Pfam Glyco_hydro_31 UniProtKB/Swiss-Prot
PhenoGen Myorg PhenoGen
Superfamily-SCOP SSF51445 UniProtKB/Swiss-Prot
UniProt A2ANN7_MOUSE UniProtKB/TrEMBL
  MYORG_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A2ANN6 UniProtKB/Swiss-Prot
  B2RU42 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-26 Myorg  myogenesis regulating glycosidase (putative)  AI464131  expressed sequence AI464131  Symbol and/or name change 5135510 APPROVED