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Gene: IL7R (interleukin 7 receptor) Homo sapiens
Symbol: IL7R
Name: interleukin 7 receptor
Description: Exhibits cytokine receptor activity. Involved in positive regulation of cell population proliferation and positive regulation of receptor signaling pathway via STAT. Predicted to localize to clathrin-coated vesicle membrane and plasma membrane. Implicated in severe combined immunodeficiency and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD127; CD127 antigen; CDW127; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; IL7RA; ILRA; interleukin 7 receptor alpha chain; interleukin 7 receptor isoform H5-6; interleukin-7 receptor subunit alpha
Mus musculus (house mouse) : Il7r (interleukin 7 receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il7r (interleukin 7 receptor)
Chinchilla lanigera (long-tailed chinchilla) : Il7r (interleukin 7 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : IL7R (interleukin 7 receptor)
Canis lupus familiaris (dog) : IL7R (interleukin 7 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il7r (interleukin 7 receptor)
Sus scrofa (pig) : IL7R (interleukin 7 receptor)
Chlorocebus sabaeus (African green monkey) : IL7R (interleukin 7 receptor)
Heterocephalus glaber (naked mole-rat) : Il7r (interleukin 7 receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl535,852,695 - 35,879,603 (+)EnsemblGRCh38hg38GRCh38
GRCh38535,856,891 - 35,879,603 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37535,856,977 - 35,879,705 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36535,892,748 - 35,912,681 (+)NCBINCBI36hg18NCBI36
Build 34535,892,747 - 35,912,678NCBI
Celera535,746,654 - 35,762,626 (+)NCBI
Cytogenetic Map5p13.2NCBI
HuRef535,806,996 - 35,829,599 (+)NCBIHuRef
CHM1_1535,859,671 - 35,882,400 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on IL7R
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320295
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.