Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane | multiple interactions | ISO | Ahcyl1 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:19414516 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AHCYL1 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | affects expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | Ethinyl Estradiol affects the expression of AHCYL1 mRNA | CTD | PMID:26865667 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of AHCYL1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Ahcyl1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of AHCYL1 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of AHCYL1 mRNA | CTD | PMID:19465110 | 2,4,6-tribromophenol | decreases expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,6-dinitrotoluene | affects expression | ISO | Ahcyl1 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of AHCYL1 mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | decreases expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of AHCYL1 mRNA | CTD | PMID:30851411 | 3',5'-cyclic AMP | multiple interactions | ISO | Ahcyl1 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:19414516 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of AHCYL1 protein | CTD | PMID:31675489 | 3,4-methylenedioxymethamphetamine | increases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of AHCYL1 mRNA | CTD | PMID:20188158 | 3,4-methylenedioxymethamphetamine | decreases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of AHCYL1 mRNA | CTD | PMID:26251327 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | AHCYL1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of AHCYL1 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of AHCYL1 mRNA | CTD | PMID:28628672 | 4,4'-diaminodiphenylmethane | affects expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane affects the expression of AHCYL1 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | increases expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of AHCYL1 protein | CTD | PMID:34186270 | 4,4'-sulfonyldiphenol | affects expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | bisphenol S affects the expression of AHCYL1 protein | CTD | PMID:31945527 | 7,12-dimethyltetraphene | affects expression | EXP | | 6480464 | 9 more ... | CTD | PMID:21785161 | acrylamide | decreases expression | ISO | Ahcyl1 (Rattus norvegicus) | 6480464 | Acrylamide results in decreased expression of AHCYL1 mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of AHCYL1 mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | decreases expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of AHCYL1 mRNA | CTD | PMID:33167477 | arsane | affects methylation | ISO | AHCYL1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of AHCYL1 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | AHCYL1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of AHCYL1 gene | CTD | PMID:25304211 | arsenous acid | increases expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of AHCYL1 mRNA | CTD | PMID:22521957 | benzo[a]pyrene | affects methylation | ISO | AHCYL1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of AHCYL1 promoter | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | increases expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | bisphenol A | affects expression | ISO | Ahcyl1 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of AHCYL1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of AHCYL1 protein | CTD | PMID:31675489 and PMID:34186270 | bisphenol A | decreases expression | ISO | Ahcyl1 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of AHCYL1 mRNA | CTD | PMID:34947998 | bisphenol A | multiple interactions | ISO | AHCYL1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of AHCYL1 mRNA | CTD | PMID:28628672 | Bisphenol B | increases expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of AHCYL1 protein | CTD | PMID:34186270 | bisphenol F | multiple interactions | ISO | AHCYL1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of AHCYL1 mRNA | CTD | PMID:28628672 | butanal | decreases expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of AHCYL1 mRNA | CTD | PMID:26079696 | C60 fullerene | increases expression | ISO | Ahcyl1 (Rattus norvegicus) | 6480464 | fullerene C60 results in increased expression of AHCYL1 mRNA | CTD | PMID:19167457 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes and Carbon analog results in increased expression of AHCYL1 mRNA | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | AHCYL1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to AHCYL1 gene] | CTD | PMID:28238834 | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of AHCYL1 mRNA | CTD | PMID:37019170 | cisplatin | affects response to substance | ISO | AHCYL1 (Homo sapiens) | 6480464 | AHCYL1 protein affects the susceptibility to Cisplatin | CTD | PMID:16217747 | clobetasol | increases expression | EXP | | 6480464 | Clobetasol results in increased expression of AHCYL1 mRNA | CTD | PMID:27462272 | coumestrol | decreases expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of AHCYL1 mRNA | CTD | PMID:19167446 | decabromodiphenyl ether | decreases expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in decreased expression of AHCYL1 protein | CTD | PMID:31675489 | dexamethasone | multiple interactions | ISO | AHCYL1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of AHCYL1 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of AHCYL1 mRNA | CTD | PMID:28628672 | diarsenic trioxide | increases expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of AHCYL1 mRNA | CTD | PMID:22521957 | diethyl maleate | increases expression | EXP | | 6480464 | diethyl maleate results in increased expression of AHCYL1 mRNA | CTD | PMID:25270620 | ethanol | multiple interactions | EXP | | 6480464 | Ethanol affects the expression of and affects the splicing of AHCYL1 mRNA | CTD | PMID:30319688 | etoposide | affects response to substance | ISO | AHCYL1 (Homo sapiens) | 6480464 | AHCYL1 protein affects the susceptibility to Etoposide | CTD | PMID:16217747 | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of AHCYL1 mRNA | CTD | PMID:25629700 | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of AHCYL1 mRNA | CTD | PMID:22206623 | genistein | affects expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | Genistein affects the expression of AHCYL1 mRNA | CTD | PMID:26865667 | gentamycin | increases expression | ISO | Ahcyl1 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of AHCYL1 mRNA | CTD | PMID:22061828 | indometacin | multiple interactions | ISO | AHCYL1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of AHCYL1 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of AHCYL1 mRNA | CTD | PMID:28628672 | irinotecan | affects expression | ISO | Ahcyl1 (Rattus norvegicus) | 6480464 | Irinotecan affects the expression of AHCYL1 mRNA | CTD | PMID:20097248 | ivermectin | decreases expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of AHCYL1 protein | CTD | PMID:32959892 | methapyrilene | decreases expression | ISO | Ahcyl1 (Rattus norvegicus) | 6480464 | Methapyrilene results in decreased expression of AHCYL1 mRNA | CTD | PMID:30467583 | methidathion | increases expression | EXP | | 6480464 | methidathion results in increased expression of AHCYL1 mRNA | CTD | PMID:34813904 | mitomycin C | affects response to substance | ISO | AHCYL1 (Homo sapiens) | 6480464 | AHCYL1 protein affects the susceptibility to Mitomycin | CTD | PMID:16217747 | mitoxantrone | affects response to substance | ISO | AHCYL1 (Homo sapiens) | 6480464 | AHCYL1 protein affects the susceptibility to Mitoxantrone | CTD | PMID:16217747 | nefazodone | increases expression | ISO | Ahcyl1 (Rattus norvegicus) | 6480464 | nefazodone results in increased expression of AHCYL1 mRNA | CTD | PMID:24136188 | nickel atom | decreases expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | Nickel results in decreased expression of AHCYL1 mRNA | CTD | PMID:23195993 | nickel sulfate | affects expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | nickel sulfate affects the expression of AHCYL1 mRNA | CTD | PMID:18202158 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of AHCYL1 mRNA | CTD | PMID:17562736 | phenobarbital | affects expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of AHCYL1 mRNA | CTD | PMID:19159669 | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of AHCYL1 mRNA | CTD | PMID:23091169 | poly(I:C) | multiple interactions | ISO | Ahcyl1 (Rattus norvegicus) | 6480464 | [Poly I-C co-treated with HU 211] results in decreased expression of AHCYL1 mRNA | CTD | PMID:26923065 | rac-lactic acid | decreases expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of AHCYL1 mRNA | CTD | PMID:30851411 | raloxifene | affects expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | Raloxifene Hydrochloride affects the expression of AHCYL1 mRNA | CTD | PMID:14699072 | resveratrol | multiple interactions | ISO | AHCYL1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of AHCYL1 mRNA | CTD | PMID:23557933 | rotenone | decreases expression | ISO | Ahcyl1 (Rattus norvegicus) | 6480464 | Rotenone results in decreased expression of AHCYL1 protein | CTD | PMID:35544339 | sunitinib | increases expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of AHCYL1 mRNA | CTD | PMID:31533062 | testosterone | decreases expression | EXP | | 6480464 | Testosterone results in decreased expression of AHCYL1 mRNA | CTD | PMID:20600201 and PMID:21669218 | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of AHCYL1 mRNA | CTD | PMID:29264374 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of AHCYL1 mRNA | CTD | PMID:19448997 | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of AHCYL1 mRNA | CTD | PMID:33045310 | trovafloxacin | decreases expression | EXP | | 6480464 | trovafloxacin results in decreased expression of AHCYL1 mRNA | CTD | PMID:35537566 | urethane | decreases expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | Urethane results in decreased expression of AHCYL1 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | AHCYL1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of AHCYL1 mRNA | CTD | PMID:25979313 | |