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Gene: TBRG4 (transforming growth factor beta regulator 4) Homo sapiens
Symbol: TBRG4
Name: transforming growth factor beta regulator 4
Description: Exhibits RNA binding activity. Involved in mitochondrial mRNA processing and regulation of mitochondrial mRNA stability. Localizes to the mitochondrial matrix; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cell cycle progression 2 protein; cell cycle progression protein 2; cell cycle progression restoration protein 2; CPR2; FAST kinase domain-containing protein 4; FAST kinase domains 4; FASTKD4; H_TD2522F11.8; KIAA0948
Mus musculus (house mouse) : Tbrg4 (transforming growth factor beta regulated gene 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tbrg4 (transforming growth factor beta regulator 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbrg4 (transforming growth factor beta regulator 4)
Pan paniscus (bonobo/pygmy chimpanzee) : TBRG4 (transforming growth factor beta regulator 4)
Canis lupus familiaris (dog) : TBRG4 (transforming growth factor beta regulator 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbrg4 (transforming growth factor beta regulator 4)
Sus scrofa (pig) : TBRG4 (transforming growth factor beta regulator 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl745,100,100 - 45,112,047 (-)Ensembl
GRCh38745,100,100 - 45,111,747 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37745,139,699 - 45,151,346 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36745,106,224 - 45,117,842 (-)NCBINCBI36hg18NCBI36
Celera745,238,535 - 45,250,160 (-)NCBI
Cytogenetic Map7p13NCBI
HuRef745,023,497 - 45,035,149 (-)NCBIHuRef
CHM1_1745,143,388 - 45,155,037 (-)NCBICHM1_1
CRA_TCAGchr7v2745,178,869 - 45,190,516 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on TBRG4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320236
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.