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Gene: MAGEL2 (MAGE family member L2) Homo sapiens
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Symbol: MAGEL2
Name: MAGE family member L2
Description: Exhibits ubiquitin-protein transferase activity. Involved in Arp2/3 complex-mediated actin nucleation; protein K63-linked ubiquitination; and retrograde transport, endosome to Golgi. Localizes to the endosome. Colocalizes with the retromer complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MAGE-like 2; MAGE-like protein 2; melanoma antigen family L2; NDNL1; necdin-like protein 1; nM15; PWLS; SHFYNG
Orthologs:
Mus musculus (house mouse) : Magel2 (melanoma antigen, family L, 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Magel2 (MAGE family member L2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Magel2 (MAGE family member L2)
Pan paniscus (bonobo/pygmy chimpanzee) : MAGEL2 (MAGE family member L2)
Canis lupus familiaris (dog) : MAGEL2 (MAGE family member L2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Magel2 (MAGE family member L2)
Sus scrofa (pig) : MAGEL2 (MAGE family member L2)
Chlorocebus sabaeus (African green monkey) : MAGEL2 (MAGE family member L2)
Heterocephalus glaber (naked mole-rat) : Magel2 (MAGE family member L2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1523,643,549 - 23,647,867 (-)EnsemblGRCh38hg38GRCh38
GRCh381523,643,549 - 23,647,867 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371523,888,696 - 23,892,993 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361521,439,789 - 21,442,268 (-)NCBINCBI36hg18NCBI36
Build 341521,439,787 - 21,442,082NCBI
Celera152,049,600 - 2,053,898 (-)NCBI
Cytogenetic Map15q11.2NCBI
HuRef152,024,179 - 2,028,378 (-)NCBIHuRef
CHM1_11523,838,991 - 23,843,288 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MAGEL2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320098
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.