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Gene: ATP8A1 (ATPase phospholipid transporting 8A1) Homo sapiens
Symbol: ATP8A1
Name: ATPase phospholipid transporting 8A1
Description: The P-type adenosinetriphosphatases (P-type ATPases) are a family of proteins which use the free energy of ATP hydrolysis to drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily catalyzes transport of heavy metal ions. Another subfamily transports non-heavy metal ions (NMHI). The protein encoded by this gene is a member of the third subfamily of P-type ATPases and acts to transport amphipaths, such as phosphatidylserine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: aminophospholipid translocase; ATPase class I type 8A member 1; ATPase II; ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1; ATPASEII; ATPIA; ATPP2; chromaffin granule ATPase II; MGC130042; MGC130043; MGC26327; P4-ATPase flippase complex alpha subunit ATP8A1; phospholipid-transporting ATPase IA; probable phospholipid-transporting ATPase IA
Mus musculus (house mouse) : Atp8a1 (ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Atp8a1 (ATPase phospholipid transporting 8A1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp8a1 (ATPase phospholipid transporting 8A1)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP8A1 (ATPase phospholipid transporting 8A1)
Canis lupus familiaris (dog) : ATP8A1 (ATPase phospholipid transporting 8A1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp8a1 (ATPase phospholipid transporting 8A1)
Sus scrofa (pig) : ATP8A1 (ATPase phospholipid transporting 8A1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38442,408,373 - 42,657,105 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37442,410,390 - 42,659,122 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36442,105,147 - 42,353,879 (-)NCBINCBI36hg18NCBI36
Build 34442,255,562 - 42,499,818NCBI
Celera442,858,235 - 43,107,011 (-)NCBI
Cytogenetic Map4p13NCBI
HuRef441,731,596 - 41,980,330 (-)NCBIHuRef
CHM1_1442,410,660 - 42,659,431 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ATP8A1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320053
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.