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Gene: ATP8A1 (ATPase phospholipid transporting 8A1) Homo sapiens
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Symbol: ATP8A1
Name: ATPase phospholipid transporting 8A1
Description: The P-type adenosinetriphosphatases (P-type ATPases) are a family of proteins which use the free energy of ATP hydrolysis to drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily catalyzes transport of heavy metal ions. Another subfamily transports non-heavy metal ions (NMHI). The protein encoded by this gene is a member of the third subfamily of P-type ATPases and acts to transport amphipaths, such as phosphatidylserine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: aminophospholipid translocase; ATPase class I type 8A member 1; ATPase II; ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1; ATPASEII; ATPIA; ATPP2; chromaffin granule ATPase II; MGC130042; MGC130043; MGC26327; P4-ATPase flippase complex alpha subunit ATP8A1; phospholipid-transporting ATPase IA; probable phospholipid-transporting ATPase IA
Orthologs:
Mus musculus (house mouse) : Atp8a1 (ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Atp8a1 (ATPase phospholipid transporting 8A1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp8a1 (ATPase phospholipid transporting 8A1)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP8A1 (ATPase phospholipid transporting 8A1)
Canis lupus familiaris (dog) : ATP8A1 (ATPase phospholipid transporting 8A1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp8a1 (ATPase phospholipid transporting 8A1)
Sus scrofa (pig) : ATP8A1 (ATPase phospholipid transporting 8A1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38442,408,373 - 42,657,105 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37442,410,390 - 42,659,122 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36442,105,147 - 42,353,879 (-)NCBINCBI36hg18NCBI36
Build 34442,255,562 - 42,499,818NCBI
Celera442,858,235 - 43,107,011 (-)NCBI
Cytogenetic Map4p13NCBI
HuRef441,731,596 - 41,980,330 (-)NCBIHuRef
CHM1_1442,410,660 - 42,659,431 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
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Genomics

Comparative Map Data
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miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ATP8A1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320053
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.