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Gene: DLX1 (distal-less homeobox 1) Homo sapiens
Symbol: DLX1
Name: distal-less homeobox 1
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in cellular response to growth factor stimulus; negative regulation of cellular response to transforming growth factor beta stimulus; and regulation of transcription by RNA polymerase II. Localizes to the nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: distal-less homeo box 1; homeobox protein DLX-1
Mus musculus (house mouse) : Dlx1 (distal-less homeobox 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dlx1 (distal-less homeobox 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dlx1 (distal-less homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DLX1 (distal-less homeobox 1)
Canis lupus familiaris (dog) : DLX1 (distal-less homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dlx1 (distal-less homeobox 1)
Sus scrofa (pig) : DLX1 (distal-less homeobox 1)
Chlorocebus sabaeus (African green monkey) : DLX1 (distal-less homeobox 1)
Heterocephalus glaber (naked mole-rat) : Dlx1 (distal-less homeobox 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2172,084,740 - 172,089,677 (+)Ensembl
GRCh382172,085,507 - 172,089,674 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372172,950,208 - 172,954,402 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362172,658,454 - 172,662,648 (+)NCBINCBI36hg18NCBI36
Celera2166,566,309 - 166,570,503 (+)NCBI
Cytogenetic Map2q31.1NCBI
HuRef2164,830,459 - 164,834,653 (+)NCBIHuRef
CHM1_12172,957,684 - 172,961,878 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on DLX1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1320012
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.