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Gene: INSM1 (INSM transcriptional repressor 1) Homo sapiens
Symbol: INSM1
Name: INSM transcriptional repressor 1
Description: Exhibits several functions, including DNA binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and cyclin binding activity. Involved in several processes, including negative regulation of nitrogen compound metabolic process; positive regulation of cell cycle arrest; and transdifferentiation. Localizes to transcription repressor complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: IA-1; IA1; insulinoma associated 1; insulinoma-associated 1; insulinoma-associated protein 1; zinc finger protein IA-1
Mus musculus (house mouse) : Insm1 (insulinoma-associated 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Insm1 (INSM transcriptional repressor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Insm1 (INSM transcriptional repressor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : INSM1 (INSM transcriptional repressor 1)
Canis lupus familiaris (dog) : INSM1 (INSM transcriptional repressor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Insm1 (INSM transcriptional repressor 1)
Sus scrofa (pig) : INSM1 (INSM transcriptional repressor 1)
Chlorocebus sabaeus (African green monkey) : INSM1 (INSM transcriptional repressor 1)
Heterocephalus glaber (naked mole-rat) : Insm1 (INSM transcriptional repressor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2020,368,104 - 20,370,949 (+)EnsemblGRCh38hg38GRCh38
GRCh382020,368,104 - 20,370,949 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372020,348,765 - 20,351,593 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362020,296,765 - 20,299,593 (+)NCBINCBI36hg18NCBI36
Build 342020,296,764 - 20,299,590NCBI
Celera2020,422,836 - 20,425,664 (+)NCBI
Cytogenetic Map20p11.23NCBI
HuRef2020,312,192 - 20,314,947 (+)NCBIHuRef
CHM1_12020,349,234 - 20,352,014 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on INSM1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319934
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-07-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.