Cend1 (cell cycle exit and neuronal differentiation 1) - Rat Genome Database

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Gene: Cend1 (cell cycle exit and neuronal differentiation 1) Mus musculus
Analyze
Symbol: Cend1
Name: cell cycle exit and neuronal differentiation 1
RGD ID: 1319728
MGI Page MGI
Description: Involved in neuron differentiation. Acts upstream of or within adult walking behavior; hindbrain development; and negative regulation of cerebellar granule cell precursor proliferation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to colocalize with mitochondrion and vesicle. Is expressed in central nervous system; peripheral nervous system ganglion; sensory organ; and urethra. Orthologous to human CEND1 (cell cycle exit and neuronal differentiation 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1500001H12Rik; AI415214; BM88; BM88 antigen; cell cycle exit and neuronal differentiation protein 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397141,006,359 - 141,009,475 (-)NCBIGRCm39mm39
GRCm39 Ensembl7141,006,359 - 141,009,404 (-)Ensembl
GRCm387141,426,446 - 141,429,562 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7141,426,446 - 141,429,491 (-)EnsemblGRCm38mm10GRCm38
MGSCv377148,612,350 - 148,615,319 (-)NCBIGRCm37mm9NCBIm37
MGSCv367141,277,769 - 141,280,740 (-)NCBImm8
Celera7141,220,197 - 141,223,166 (-)NCBICelera
Cytogenetic Map7F5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Mouse MP Annotation Import Pipeline RGD automated import pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11311134   PMID:12466851   PMID:12477932   PMID:15489334   PMID:15548196   PMID:16141072   PMID:16141073  
PMID:16949349   PMID:17971443   PMID:18499894   PMID:19877281   PMID:19911428   PMID:20153830   PMID:21267068   PMID:21873635   PMID:22794259   PMID:23658157   PMID:24312406   PMID:26321141  
PMID:30068389   PMID:30562941   PMID:30760981   PMID:32325033   PMID:32703236  


Genomics

Comparative Map Data
Cend1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397141,006,359 - 141,009,475 (-)NCBIGRCm39mm39
GRCm39 Ensembl7141,006,359 - 141,009,404 (-)Ensembl
GRCm387141,426,446 - 141,429,562 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7141,426,446 - 141,429,491 (-)EnsemblGRCm38mm10GRCm38
MGSCv377148,612,350 - 148,615,319 (-)NCBIGRCm37mm9NCBIm37
MGSCv367141,277,769 - 141,280,740 (-)NCBImm8
Celera7141,220,197 - 141,223,166 (-)NCBICelera
Cytogenetic Map7F5NCBI
CEND1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811787,115 - 790,090 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl11787,115 - 790,113 (-)EnsemblGRCh38hg38GRCh38
GRCh3711787,115 - 790,090 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611777,110 - 780,126 (-)NCBINCBI36hg18NCBI36
Celera11853,614 - 856,673 (-)NCBI
Cytogenetic Map11p15.5NCBI
HuRef11603,877 - 606,892 (-)NCBIHuRef
CHM1_111785,939 - 788,955 (-)NCBICHM1_1
T2T-CHM13v2.011838,549 - 841,523 (-)NCBI
Cend1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21196,525,153 - 196,528,152 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1196,523,920 - 196,528,302 (-)Ensembl
Rnor_6.01214,407,072 - 214,410,069 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1214,408,100 - 214,408,549 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1213,970,174 - 213,973,163 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01220,887,395 - 220,890,392 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41201,614,373 - 201,617,370 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11201,767,730 - 201,770,725 (-)NCBI
Celera1194,158,655 - 194,161,652 (-)NCBICelera
Cytogenetic Map1q41NCBI
Cend1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547611,339,586 - 11,341,996 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547611,339,586 - 11,341,996 (+)NCBIChiLan1.0ChiLan1.0
CEND1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.111848,633 - 851,665 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11849,678 - 850,127 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v011804,517 - 807,608 (-)NCBIMhudiblu_PPA_v0panPan3
CEND1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11825,782,012 - 25,783,897 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1825,454,271 - 25,457,085 (-)NCBI
ROS_Cfam_1.01826,389,948 - 26,392,761 (-)NCBI
ROS_Cfam_1.0 Ensembl1826,390,816 - 26,391,265 (-)Ensembl
UMICH_Zoey_3.11825,899,451 - 25,902,264 (-)NCBI
UNSW_CanFamBas_1.01825,544,463 - 25,547,277 (-)NCBI
UU_Cfam_GSD_1.01826,156,775 - 26,159,589 (-)NCBI
Cend1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947554,859 - 557,779 (-)NCBI
SpeTri2.0NW_004936888554,859 - 557,759 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CEND1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2487,821 - 490,699 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12487,817 - 490,704 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22183,665 - 186,548 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CEND1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11590,581 - 593,599 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1591,585 - 592,043 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603897,682,822 - 97,685,859 (-)NCBIVero_WHO_p1.0
Cend1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476621,718,169 - 21,720,907 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462476621,718,023 - 21,720,907 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
AI415214  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387141,426,527 - 141,426,757UniSTSGRCm38
MGSCv377148,612,426 - 148,612,656UniSTSGRCm37
Celera7141,220,273 - 141,220,503UniSTS
Cytogenetic Map7F5UniSTS
Whitehead/MRC_RH71427.73UniSTS
AI060884  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387141,430,489 - 141,430,645UniSTSGRCm38
MGSCv377148,616,388 - 148,616,544UniSTSGRCm37
Celera7141,224,235 - 141,224,391UniSTS
Cytogenetic Map7F5UniSTS
Whitehead/MRC_RH71434.24UniSTS
UniSTS:235811  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387141,429,867 - 141,430,106UniSTSGRCm38
MGSCv377148,615,766 - 148,616,005UniSTSGRCm37
Celera7141,223,613 - 141,223,852UniSTS
Cytogenetic Map7F5UniSTS
Cend1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387141,427,537 - 141,427,717UniSTSGRCm38
Celera7141,221,283 - 141,221,463UniSTS
Cytogenetic Map7F5UniSTS
cM Map786.77UniSTS


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
14700684Civq1_mcerebral infarct volume QTL 1 (mouse)7109707335143707335Mouse
14700687Civq5_mcerebral infarct volume QTL 5 (mouse)7109707335143707335Mouse
14700688Civq6_mcerebral infarct volume QTL 6 (mouse)7109707335143707335Mouse
11059562Lmr21b_mleishmaniasis resistance 21b (mouse)7110967235144967336Mouse
10402499Lmr21_mleishmaniasis resistance 21 (mouse)Not determined7110967235144967336Mouse
1302032Alcp12_malcohol preference locus 12 (mouse)Not determined7111166122144995196Mouse
1301898Alcp14_malcohol preference locus 14 (mouse)Not determined7111166122144995196Mouse
1300670Sluc19_msusceptibility to lung cancer 19 (mouse)Not determined7111166122144995196Mouse
4142444Femwf5_mfemur work to failure 5 (mouse)Not determined112552248144995196Mouse
1300747Skts2_mskin tumor susceptibility 2 (mouse)Not determined7112922733144995196Mouse
1300677Bmd9_mbone mineral density 9 (mouse)Not determined7116634089144995196Mouse
1357711Adbg1_madult body growth 1 (mouse)Not determined7118693381144398314Mouse
1301773Stheal7_msoft tissue heal 7 (mouse)Not determined7119132573144995196Mouse
1301590Pbwg3_mpostnatal body weight growth 3 (mouse)Not determined7127311241144995196Mouse
1300566Sluc8_msusceptibility to lung cancer 8 (mouse)Not determined7127398151144995196Mouse
14746988Manh63_mmandible shape 63 (mouse)7127735437144995196Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1371
Count of miRNA genes:305
Interacting mature miRNAs:340
Transcripts:ENSMUST00000084436, ENSMUST00000124444, ENSMUST00000137488, ENSMUST00000164387
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000084436   ⟹   ENSMUSP00000081476
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7141,006,359 - 141,009,338 (-)Ensembl
GRCm38.p6 Ensembl7141,426,446 - 141,429,425 (-)Ensembl
RefSeq Acc Id: ENSMUST00000124444   ⟹   ENSMUSP00000118591
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7141,006,359 - 141,009,404 (-)Ensembl
GRCm38.p6 Ensembl7141,426,446 - 141,429,491 (-)Ensembl
RefSeq Acc Id: ENSMUST00000137488   ⟹   ENSMUSP00000123334
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7141,006,364 - 141,009,331 (-)Ensembl
GRCm38.p6 Ensembl7141,426,451 - 141,429,418 (-)Ensembl
RefSeq Acc Id: ENSMUST00000164387   ⟹   ENSMUSP00000131085
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7141,006,364 - 141,009,264 (-)Ensembl
GRCm38.p6 Ensembl7141,426,451 - 141,429,351 (-)Ensembl
RefSeq Acc Id: NM_001360485   ⟹   NP_001347414
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397141,006,359 - 141,009,475 (-)NCBI
GRCm387141,426,446 - 141,429,562 (-)NCBI
Sequence:
RefSeq Acc Id: NM_021316   ⟹   NP_067291
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397141,006,359 - 141,009,475 (-)NCBI
GRCm387141,426,446 - 141,429,562 (-)NCBI
MGSCv377148,612,350 - 148,615,319 (-)RGD
Celera7141,220,197 - 141,223,166 (-)RGD
cM Map7 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_067291   ⟸   NM_021316
- UniProtKB: Q9JKC6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001347414   ⟸   NM_001360485
RefSeq Acc Id: ENSMUSP00000131085   ⟸   ENSMUST00000164387
RefSeq Acc Id: ENSMUSP00000118591   ⟸   ENSMUST00000124444
RefSeq Acc Id: ENSMUSP00000081476   ⟸   ENSMUST00000084436
RefSeq Acc Id: ENSMUSP00000123334   ⟸   ENSMUST00000137488

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JKC6-F1-model_v2 AlphaFold Q9JKC6 1-149 view protein structure

Promoters
RGD ID:8666115
Promoter ID:EPDNEW_M11089
Type:initiation region
Name:Cend1_1
Description:Mus musculus cell cycle exit and neuronal differentiation 1 ,transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387141,429,398 - 141,429,458EPDNEW
RGD ID:6840824
Promoter ID:MM_KWN:53259
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000086111,   OTTMUST00000086112,   OTTMUST00000086113,   OTTMUST00000086114
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367148,615,321 - 148,616,372 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1929898 AgrOrtholog
Ensembl Genes ENSMUSG00000060240 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000081476 UniProtKB/Swiss-Prot
  ENSMUSP00000118591 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000123334 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000131085 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000084436 UniProtKB/Swiss-Prot
  ENSMUST00000124444 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000137488 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000164387 UniProtKB/Swiss-Prot
InterPro Cend1 UniProtKB/Swiss-Prot
KEGG Report mmu:57754 UniProtKB/Swiss-Prot
MGD MGI:1929898 ENTREZGENE
NCBI Gene 57754 ENTREZGENE
PANTHER PTHR36683 UniProtKB/Swiss-Prot
Pfam CEND1 UniProtKB/Swiss-Prot
PhenoGen Cend1 PhenoGen
UniProt CEND_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q9DBA0 UniProtKB/Swiss-Prot