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Gene: Scap (SREBF chaperone) Mus musculus
Symbol: Scap
Name: SREBF chaperone
Description: ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN cellular lipid metabolic process; cholesterol metabolic process; immune response; PARTICIPATES IN sterol regulatory element-binding protein signaling pathway; ASSOCIATED WITH abnormal cholesterol homeostasis; abnormal lipid homeostasis; decreased circulating free fatty acid level; ASSOCIATED WITH Diabetes Mellitus, Experimental (ortholog); hepatocellular carcinoma (ortholog); Hypercholesterolemia (ortholog); FOUND IN endoplasmic reticulum membrane; intracellular membrane-bounded organelle (ortholog); protein-containing complex (ortholog); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; bezafibrate
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9530044G19; mKIAA0199; Sreb cleavage-activating protein; SREBP cleavage activating protein; SREBP cleavage-activating protein; sterol regulatory element-binding protein cleavage-activating protein
Homo sapiens (human) : SCAP (SREBF chaperone)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Scap (SREBF chaperone)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Scap (SREBF chaperone)
Pan paniscus (bonobo/pygmy chimpanzee) : SCAP (SREBF chaperone)
Canis lupus familiaris (dog) : SCAP (SREBF chaperone)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scap (SREBF chaperone)
Sus scrofa (pig) : SCAP (SREBF chaperone)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm389110,333,288 - 110,384,949 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379110,235,797 - 110,287,450 (+)NCBIGRCm37mm9NCBIm37
MGSCv369110,178,523 - 110,230,113 (+)NCBImm8
Celera9110,062,300 - 110,113,908 (+)NCBICelera
Cytogenetic Map9 F2NCBI
cM Map959.91NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Scap
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319695
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.