F11 (coagulation factor XI) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: F11 (coagulation factor XI) Mus musculus
Analyze
Symbol: F11
Name: coagulation factor XI
RGD ID: 1319674
MGI Page MGI
Description: Predicted to enable identical protein binding activity and serine-type aminopeptidase activity. Acts upstream of or within regulation of blood coagulation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in liver; liver left lobe; and liver right lobe. Used to study factor XI deficiency. Human ortholog(s) of this gene implicated in factor XI deficiency and thrombosis. Orthologous to human F11 (coagulation factor XI).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 1600027G01Rik; AI503996; Cf11; FX; FXI; plasma thromboplastin antecedent; PTA
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39845,693,696 - 45,715,092 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl845,694,211 - 45,715,068 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38845,240,659 - 45,262,055 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl845,241,174 - 45,262,031 (-)Ensemblmm10GRCm38
MGSCv37846,326,524 - 46,347,385 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36846,739,987 - 46,760,848 (-)NCBIMGSCv36mm8
Celera847,928,261 - 47,949,034 (-)NCBICelera
Cytogenetic Map8B1.1NCBI
cM Map825.14NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (EXP)
(S)-amphetamine  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
4,4'-sulfonyldiphenol  (EXP)
acetamide  (ISO)
aflatoxin B1  (EXP,ISO)
amiodarone  (EXP)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calcium dichloride  (ISO)
carbon nanotube  (EXP)
clofibrate  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (EXP,ISO)
dextran sulfate  (EXP)
dichloroacetic acid  (EXP)
dicrotophos  (ISO)
dorsomorphin  (ISO)
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor  (ISO)
endosulfan  (ISO)
ethanol  (EXP)
Ethyl icosapentate  (ISO)
fenthion  (EXP)
genistein  (EXP)
hexadecanoic acid  (ISO)
inulin  (EXP)
kaolin  (ISO)
methotrexate  (EXP)
N-Nitrosopyrrolidine  (ISO)
nitrofen  (ISO)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (EXP)
pirinixic acid  (EXP)
raloxifene  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
tetrachloroethene  (EXP)
tetrachloromethane  (EXP,ISO)
Theaflavin 3,3'-digallate  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
trichloroethene  (ISO)
Triptolide  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Factor XI (plasma thromboplastin antecedent) deficiency in Ashkenazi Jews is a bleeding disorder that can result from three types of point mutations. Asakai R, etal., Proc Natl Acad Sci U S A. 1989 Oct;86(20):7667-71.
2. Noonan syndrome: partial factor XI deficiency. de Haan M, etal., Am J Med Genet. 1988 Feb;29(2):277-82.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis. Kleinschnitz C, etal., J Exp Med. 2006 Mar 20;203(3):513-8. Epub 2006 Mar 13.
5. Anti-c5a ameliorates coagulation/fibrinolytic protein changes in a rat model of sepsis. Laudes IJ, etal., Am J Pathol. 2002 May;160(5):1867-75.
6. Genetic variants associated with deep vein thrombosis: the F11 locus. Li Y, etal., J Thromb Haemost. 2009 Nov;7(11):1802-8. doi: 10.1111/j.1538-7836.2009.03544.x. Epub 2009 Jul 6.
7. The F11 rs2289252 polymorphism is associated with FXI activity levels and APTT ratio in women with thrombosis. Lunghi B, etal., Thromb Res. 2012 Sep;130(3):563-4. doi: 10.1016/j.thromres.2012.05.004. Epub 2012 May 25.
8. High levels of coagulation factor XI as a risk factor for venous thrombosis. Meijers JC, etal., N Engl J Med. 2000 Mar 9;342(10):696-701.
9. MGDs mouse GO annotations MGD data from the GO Consortium
10. Effect of dienogest on bleeding time, coagulation, fibrinolysis, and platelet aggregation in female rats. Nobukata H, etal., Toxicol Lett. 1999 Jan 11;104(1-2):93-101.
11. Blood coagulation. Norris LA, Best Pract Res Clin Obstet Gynaecol. 2003 Jun;17(3):369-83.
12. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
13. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
14. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
15. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
16. Mouse MP Annotation Import Pipeline RGD automated import pipeline
17. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
19. A novel mutation that leads to a congenital factor XI deficiency in a Japanese family. Sato E, etal., Am J Hematol. 2000 Apr;63(4):165-9.
20. How it all starts: Initiation of the clotting cascade. Smith SA, etal., Crit Rev Biochem Mol Biol. 2015;50(4):326-36. doi: 10.3109/10409238.2015.1050550. Epub 2015 May 28.
21. Activity of coagulation factor XI in patients with spontaneous miscarriage: the presence of risk alleles. Sokol J, etal., J Obstet Gynaecol. 2015;35(6):621-4. doi: 10.3109/01443615.2014.991284. Epub 2014 Dec 17.
22. Molecular genetic analysis of factor XI deficiency: identification of five novel gene alterations and the origin of type II mutation in Portuguese families. Ventura C, etal., Thromb Haemost. 2000 Nov;84(5):833-40.
Additional References at PubMed
PMID:7613034   PMID:9242536   PMID:9518045   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11159184   PMID:11841337   PMID:12008966   PMID:12477932   PMID:15733058   PMID:15985536  
PMID:15996948   PMID:16009717   PMID:16141072   PMID:16141073   PMID:18491973   PMID:19661487   PMID:20005807   PMID:20634381   PMID:21267068   PMID:21724997   PMID:22006565   PMID:23472758  
PMID:23487423   PMID:23515926   PMID:23929304   PMID:24066149   PMID:24118982   PMID:24947525   PMID:26153520   PMID:26800563   PMID:26817955   PMID:27046148   PMID:27188843   PMID:27596064  
PMID:27913422   PMID:28148841   PMID:28492700   PMID:28677246   PMID:29207114   PMID:29365314   PMID:30591525   PMID:30898865   PMID:31125187   PMID:31766871   PMID:36137043   PMID:36724509  


Genomics

Comparative Map Data
F11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39845,693,696 - 45,715,092 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl845,694,211 - 45,715,068 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38845,240,659 - 45,262,055 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl845,241,174 - 45,262,031 (-)Ensemblmm10GRCm38
MGSCv37846,326,524 - 46,347,385 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36846,739,987 - 46,760,848 (-)NCBIMGSCv36mm8
Celera847,928,261 - 47,949,034 (-)NCBICelera
Cytogenetic Map8B1.1NCBI
cM Map825.14NCBI
F11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384186,266,189 - 186,289,681 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4186,266,189 - 186,289,681 (+)Ensemblhg38GRCh38
GRCh374187,187,343 - 187,210,835 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364187,424,112 - 187,447,829 (+)NCBIBuild 36Build 36hg18NCBI36
Build 344187,562,426 - 187,585,083NCBI
Celera4184,511,477 - 184,537,546 (+)NCBICelera
Cytogenetic Map4q35.2NCBI
HuRef4182,938,469 - 182,962,233 (+)NCBIHuRef
CHM1_14187,163,556 - 187,187,273 (+)NCBICHM1_1
T2T-CHM13v2.04189,606,162 - 189,629,664 (+)NCBIT2T-CHM13v2.0
F11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81653,720,502 - 53,741,547 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1653,718,621 - 53,740,941 (+)EnsemblGRCr8
mRatBN7.21646,987,988 - 47,009,015 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1646,986,107 - 47,008,437 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1652,378,899 - 52,400,805 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01655,756,360 - 55,778,414 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01651,018,291 - 51,040,195 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01650,179,458 - 50,201,644 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1650,179,458 - 50,201,698 (+)Ensemblrn6Rnor6.0
Rnor_5.01649,902,415 - 49,924,601 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41650,276,330 - 50,298,903 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1644,976,615 - 44,998,530 (+)NCBICelera
RGSC_v3.11650,287,001 - 50,298,978 (+)NCBI
Cytogenetic Map16q11NCBI
F11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540322,811,380 - 22,830,563 (-)Ensembl
ChiLan1.0NW_00495540322,811,211 - 22,830,281 (-)NCBIChiLan1.0ChiLan1.0
F11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23184,008,843 - 184,033,166 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14184,357,677 - 184,381,996 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04178,436,865 - 178,459,568 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14190,643,733 - 190,666,512 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4190,643,733 - 190,666,512 (+)EnsemblpanPan2panpan1.1
F11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11644,469,609 - 44,492,833 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1644,469,632 - 44,540,292 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1644,956,542 - 44,972,975 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01646,683,089 - 46,700,923 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1646,683,106 - 46,700,880 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11644,652,096 - 44,668,510 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01645,264,846 - 45,281,307 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01645,395,778 - 45,412,243 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101967202
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494334,886,563 - 34,903,578 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365543,205,539 - 3,219,311 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365543,205,539 - 3,223,228 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
F11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl179,046,002 - 9,073,520 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1179,045,990 - 9,073,552 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
F11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17132,180,026 - 132,207,081 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7132,180,336 - 132,208,155 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037112,505,568 - 112,530,733 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
F11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476917,094,169 - 17,115,222 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476917,093,643 - 17,115,716 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in F11
2225 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:83
Count of miRNA genes:75
Interacting mature miRNAs:76
Transcripts:ENSMUST00000034064
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301139Lmr10_mleishmaniasis resistance 10 (mouse)Not determined83532109757797633Mouse
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81477316071498244Mouse
11049577Lmr10b_mleishmaniasis resistance 10b (mouse)83532109757797633Mouse
4141437W10q14_mweight 10 weeks QTL 14 (mouse)Not determined3250657271740637Mouse
11049578Lmr10c_mleishmaniasis resistance 10c (mouse)83532109757797633Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83663015493455280Mouse
11041902Lmr10a_mleishmaniasis resistance 10a (mouse)83532109757797633Mouse
4141172W6q9_mweight 6 weeks QTL 9 (mouse)Not determined3250657271740637Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined835109930115563747Mouse
10043990Hbnr12_mHeligmosomoides bakeri nematode resistance 12 (mouse)Not determined83327701651290537Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832506572117965439Mouse
4140966Egq12_mearly growth QTL 12 (mouse)Not determined3250657271740637Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837867154110326632Mouse
10043974Obq30_mobesity QTL 30 (mouse)Not determined82658332260583322Mouse
1301298Pgia4_mproteoglycan induced arthritis 4 (mouse)Not determined81656937350569697Mouse
1301936Trigq2_mtriglyceride QTL 2 (mouse)Not determined83429039768290537Mouse
1300912Daq19_mdirectional asymmetry QTL 19 (mouse)Not determined81550657249506729Mouse
13524525Bodwtq7_mbody wweight QTL 7 (mouse)82824955647027681Mouse
1357811Orq3_movulation rate QTL 3 (mouse)Not determined83250657271740637Mouse
1300603Cd8ts2_mCD8 T cell subset 2 (mouse)Not determined81945501853455150Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)84016229795416226Mouse
1301088Alcw6_malcohol withdrawal 6 (mouse)Not determined81550657249506729Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84474791478748059Mouse
1301160Eae14_msusceptibility to experimental allergic encephalomyelitis 14 (mouse)Not determined81945501853455150Mouse
1301550Fembrs2_mfemur breaking strength 2 (mouse)Not determined81832109752321225Mouse

Markers in Region
AI503996  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38845,241,234 - 45,241,486UniSTSGRCm38
MGSCv37846,326,588 - 46,326,840UniSTSGRCm37
Celera847,928,325 - 47,928,577UniSTS
Cytogenetic Map8A4UniSTS
Cytogenetic Map8B1.1UniSTS
Whitehead/MRC_RH8534.59UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000034064   ⟹   ENSMUSP00000034064
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl845,694,211 - 45,715,068 (-)Ensembl
GRCm38.p6 Ensembl845,241,174 - 45,262,031 (-)Ensembl
Ensembl Acc Id: ENSMUST00000210622
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl845,703,110 - 45,715,068 (-)Ensembl
GRCm38.p6 Ensembl845,250,073 - 45,262,031 (-)Ensembl
RefSeq Acc Id: NM_001411665   ⟹   NP_001398594
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39845,693,696 - 45,715,023 (-)NCBI
RefSeq Acc Id: NM_028066   ⟹   NP_082342
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39845,693,696 - 45,715,023 (-)NCBI
GRCm38845,241,168 - 45,262,031 (-)NCBI
MGSCv37846,326,524 - 46,347,385 (-)RGD
Celera847,928,261 - 47,949,034 (-)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006509245   ⟹   XP_006509308
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39845,693,696 - 45,708,324 (-)NCBI
GRCm38845,240,659 - 45,255,287 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011242172   ⟹   XP_011240474
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39845,693,696 - 45,706,148 (-)NCBI
GRCm38845,240,659 - 45,253,111 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003947216
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39845,703,114 - 45,715,092 (-)NCBI
GRCm38845,250,077 - 45,262,055 (-)NCBI
Sequence:
RefSeq Acc Id: NP_082342   ⟸   NM_028066
- Peptide Label: isoform 1 preproprotein
- UniProtKB: Q91Y47 (UniProtKB/Swiss-Prot),   Q9DAT3 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006509308   ⟸   XM_006509245
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011240474   ⟸   XM_011242172
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSMUSP00000034064   ⟸   ENSMUST00000034064
RefSeq Acc Id: NP_001398594   ⟸   NM_001411665
- Peptide Label: isoform 2
Protein Domains
Apple   Peptidase S1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q91Y47-F1-model_v2 AlphaFold Q91Y47 1-624 view protein structure

Promoters
RGD ID:8666985
Promoter ID:EPDNEW_M11523
Type:initiation region
Name:F11_1
Description:Mus musculus coagulation factor XI , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38845,261,986 - 45,262,046EPDNEW
RGD ID:6843110
Promoter ID:MM_KWN:54294
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:NM_028066
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36846,347,111 - 46,347,611 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:99481 AgrOrtholog
Ensembl Genes ENSMUSG00000031645 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000034064 ENTREZGENE
  ENSMUST00000034064.5 UniProtKB/Swiss-Prot
  ENSMUST00000210622 ENTREZGENE
Gene3D-CATH 2.40.10.10 UniProtKB/Swiss-Prot
  Hepatocyte Growth Factor UniProtKB/Swiss-Prot
InterPro Apple UniProtKB/Swiss-Prot
  Pan_app UniProtKB/Swiss-Prot
  Peptidase_S1_PA UniProtKB/Swiss-Prot
  Peptidase_S1_PA_chymotrypsin UniProtKB/Swiss-Prot
  Peptidase_S1A UniProtKB/Swiss-Prot
  Trypsin_dom UniProtKB/Swiss-Prot
  TRYPSIN_HIS UniProtKB/Swiss-Prot
  TRYPSIN_SER UniProtKB/Swiss-Prot
KEGG Report mmu:109821 UniProtKB/Swiss-Prot
MGD MGI:99481 ENTREZGENE
NCBI Gene F11 ENTREZGENE
PANTHER ACROSIN-RELATED UniProtKB/Swiss-Prot
  HYALIN UniProtKB/Swiss-Prot
Pfam PAN_1 UniProtKB/Swiss-Prot
  Trypsin UniProtKB/Swiss-Prot
PhenoGen F11 PhenoGen
PRINTS APPLEDOMAIN UniProtKB/Swiss-Prot
  CHYMOTRYPSIN UniProtKB/Swiss-Prot
PROSITE APPLE UniProtKB/Swiss-Prot
  PAN UniProtKB/Swiss-Prot
  TRYPSIN_DOM UniProtKB/Swiss-Prot
  TRYPSIN_HIS UniProtKB/Swiss-Prot
  TRYPSIN_SER UniProtKB/Swiss-Prot
SMART APPLE UniProtKB/Swiss-Prot
  Tryp_SPc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50494 UniProtKB/Swiss-Prot
UniProt FA11_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q9DAT3 ENTREZGENE
UniProt Secondary Q9DAT3 UniProtKB/Swiss-Prot