Gene: F11 (coagulation factor XI) Mus musculus
Analyze
Symbol:
F11
Name:
coagulation factor XI
Description:
This gene encodes a glycoprotein coagulation factor that plays an important role in intrinsic pathway of blood coagulation and hemostasis. The encoded protein is an inactive zymogen that can be activated by coagulation factor XIIa, thrombin or factor XIa to generate active factor XIa protease. Mice lacking the encoded protein display a survival advantage during peritoneal sepsis and resist inflammation and bacterial accumulation upon infection with Listeria. [provided by RefSeq, Apr 2015]
Type:
protein-coding
RefSeq Status:
REVIEWED
Also known as:
1600027G01Rik; AI503996; Cf11; FXI; plasma thromboplastin antecedent; PTA
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
F11 (coagulation factor XI) HGNC
EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):
F11 (coagulation factor XI) HGNC
NCBI, OMA, HomoloGene, Panther, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
F11 (coagulation factor XI) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
F11 (coagulation factor XI) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
F11 (coagulation factor XI) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
F11 (coagulation factor XI) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
F11 (coagulation factor XI) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
KLKB1 (kallikrein B1) HGNC
OrthoDB, OrthoMCL
Alliance orthologs 3
Rattus norvegicus (Norway rat):
F11 (coagulation factor XI)
Alliance
DIOPT (Ensembl Compara, OMA, OrthoFinder, PANTHER, PhylomeDB)
Homo sapiens (human):
F11 (coagulation factor XI)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam)
Latest Assembly:
GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm38 8 45,240,659 - 45,262,050 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 MGSCv37 8 46,326,524 - 46,347,385 (-) NCBI GRCm37 mm9 NCBIm37 MGSCv36 8 46,739,987 - 46,760,848 (-) NCBI mm8 Celera 8 47,928,261 - 47,949,034 (-) NCBI Celera Cytogenetic Map 8 B1.1 NCBI cM Map 8 25.14 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - ClinVar
autistic disorder ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Autistic disorder of childhood onset ClinVar PMID:21681106 , PMID:30208311 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:25741868 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:15634276 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:11122101 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:14508802 , PMID:25741868 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:10593931 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:25741868 , PMID:27710856 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:10593931 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:19652879 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:15968392 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:16835901 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:21457405 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:16079124 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:16607084 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:25158988 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:16835901 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:27723456 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:22016685 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:16835901 , PMID:18446632 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:15870541 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:16835901 , PMID:20398070 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:12586617 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:14717969 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:15531455 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:15953011 , PMID:19652879 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:18446632 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:27710856 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:19652879 , PMID:27710856 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:24112640 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:15946525 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:23305485 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:18515884 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:19652879 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:20398070 , PMID:27067486 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:26879396 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:19367158 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:18388506 , PMID:19652879 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:16835901 , PMID:19652879 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:15026311 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:15180874 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:16835901 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:10444286 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:12716376 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:22159456 , PMID:25741868 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:12879434 , PMID:18832909 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:15953011 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:15180874 , PMID:7669672 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:9401068 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:15026311 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:7888672 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:7669672 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:22159456 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:10606881 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:15026311 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:16787881 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:21649796 , PMID:24112640 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:27067486 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:14717969 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:16607084 , PMID:16835901 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Factor XI Deficiency ClinVar PMID:15953011 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:16835901 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:11895778 , PMID:18024374 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:16835901 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:15953011 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:11127865 , PMID:18024374 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:11895778 , PMID:24112640 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:15531455 , PMID:16835901 factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by OMIM:612416 ClinVar PMID:16835901 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:12716376 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar PMID:14717969 more ... factor XI deficiency ISO RGD:1319673 8554872 ClinVar Annotator: match by term: Hereditary factor XI deficiency disease ClinVar
Imported Annotations - CTD
hypertension ISO RGD:1319673 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:6383834 Imported Annotations - MGI
factor XI deficiency IEA 13592920 OMIM:612416 MouseDO Imported Annotations - OMIM
factor XI deficiency ISO RGD:1319673 7240710 OMIM
(S)-amphetamine increases expression EXP 6480464 Dextroamphetamine results in increased expression of F11 mRNA CTD PMID:12558987 1,2-dichloroethane decreases expression EXP 6480464 ethylene dichloride results in decreased expression of F11 mRNA CTD PMID:28189721 1,2-dimethylhydrazine multiple interactions ISO RGD:1309364 6480464 [APC protein affects the susceptibility to 1, 2-Dimethylhydrazine] which results in decreased expression of F11 mRNA CTD PMID:27840820 17beta-estradiol decreases expression ISO RGD:1319673 6480464 Estradiol results in decreased expression of F11 mRNA CTD PMID:20106945 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of F11 mRNA CTD PMID:19770486 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1319673 6480464 Tetrachlorodibenzodioxin results in increased expression of F11 mRNA CTD PMID:11489354 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1309364 6480464 Tetrachlorodibenzodioxin results in decreased expression of F11 mRNA CTD PMID:21724226 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of F11 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1309364 6480464 Tetrachlorodibenzodioxin affects the expression of F11 mRNA CTD PMID:22298810 2,3,7,8-Tetrachlorodibenzofuran decreases expression ISO RGD:1309364 6480464 2 more ... CTD PMID:21724226 aflatoxin B1 affects expression ISO RGD:1319673 6480464 Aflatoxin B1 affects the expression of F11 protein CTD PMID:20106945 aflatoxin B1 decreases expression ISO RGD:1319673 6480464 Aflatoxin B1 results in decreased expression of F11 mRNA CTD PMID:27153756 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of F11 mRNA CTD PMID:19770486 amiodarone decreases expression EXP 6480464 Amiodarone results in decreased expression of F11 mRNA CTD PMID:24535564 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of F11 mRNA CTD PMID:19770486 benzo[a]pyrene increases expression ISO RGD:1319673 6480464 Benzo(a)pyrene results in increased expression of F11 mRNA CTD PMID:22316170 , PMID:26238291 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of F11 mRNA CTD PMID:19850644 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 PPARA protein promotes the reaction [Diethylhexyl Phthalate results in decreased expression of F11 mRNA] CTD PMID:19850644 bisphenol A increases expression ISO RGD:1309364 6480464 bisphenol A results in increased expression of F11 mRNA CTD PMID:25181051 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of F11 mRNA CTD PMID:30245210 butanal increases expression ISO RGD:1319673 6480464 butyraldehyde results in increased expression of F11 mRNA CTD PMID:26079696 cadmium atom decreases expression ISO RGD:1319673 6480464 Cadmium results in decreased expression of F11 mRNA CTD PMID:24376830 cadmium atom affects binding ISO RGD:1319673 6480464 F11 protein binds to Cadmium CTD PMID:23896426 cadmium dichloride decreases methylation ISO RGD:1309364 6480464 Cadmium Chloride results in decreased methylation of F11 promoter CTD PMID:22457795 calcium dichloride multiple interactions ISO RGD:1319673 6480464 [F11 protein co-treated with Calcium Chloride] results in increased activity of F9 protein CTD PMID:6604052 carbon nanotube affects expression EXP 6480464 Nanotubes, Carbon affects the expression of F11 mRNA CTD PMID:23845593 carbon nanotube decreases expression EXP 6480464 Nanotubes, Carbon analog results in decreased expression of F11 mRNA CTD PMID:25620056 clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of F11 mRNA CTD PMID:23811191 copper(II) sulfate decreases expression ISO RGD:1319673 6480464 Copper Sulfate results in decreased expression of F11 mRNA CTD PMID:19549813 cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of F11 mRNA CTD PMID:19770486 , PMID:23830897 cyclosporin A decreases expression ISO RGD:1319673 6480464 Cyclosporine results in decreased expression of F11 mRNA CTD PMID:20106945 more ... dichloroacetic acid decreases expression EXP 6480464 Dichloroacetic Acid results in decreased expression of F11 mRNA CTD PMID:28962523 dicrotophos decreases expression ISO RGD:1319673 6480464 dicrotophos results in decreased expression of F11 mRNA CTD PMID:28302478 dorsomorphin multiple interactions ISO RGD:1319673 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of F11 mRNA CTD PMID:27188386 EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor decreases expression ISO RGD:1319673 6480464 Angiotensin-Converting Enzyme Inhibitors results in decreased expression of F11 protein CTD PMID:6383834 endosulfan decreases expression ISO RGD:1309364 6480464 Endosulfan results in decreased expression of F11 mRNA CTD PMID:29391264 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of F11 mRNA CTD PMID:19167417 Ethyl icosapentate decreases activity ISO RGD:1309364 6480464 eicosapentaenoic acid ethyl ester results in decreased activity of F11 protein CTD PMID:14614217 kaolin decreases activity ISO RGD:1319673 6480464 Kaolin results in decreased activity of F11 protein CTD PMID:6604052 methotrexate affects expression EXP 6480464 Methotrexate affects the expression of F11 mRNA CTD PMID:18502557 paracetamol decreases expression ISO RGD:1319673 6480464 Acetaminophen results in decreased expression of F11 mRNA CTD PMID:27761495 , PMID:29067470 perfluorooctane-1-sulfonic acid affects expression EXP 6480464 perfluorooctane sulfonic acid affects the expression of F11 mRNA CTD PMID:19429403 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:1319673 6480464 perfluorooctane sulfonic acid results in decreased expression of F11 mRNA CTD PMID:27153767 perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of F11 mRNA CTD PMID:20936131 perfluorooctanoic acid affects expression EXP 6480464 perfluorooctanoic acid affects the expression of F11 mRNA CTD PMID:19429403 perfluorooctanoic acid increases expression ISO RGD:1319673 6480464 perfluorooctanoic acid results in increased expression of F11 mRNA CTD PMID:25868421 perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of F11 mRNA CTD PMID:18467677 , PMID:20936131 perfluorooctanoic acid multiple interactions EXP 6480464 PPARA protein promotes the reaction [perfluorooctanoic acid results in decreased expression of F11 mRNA] CTD PMID:18467677 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of F11 mRNA CTD PMID:19136022 pirinixic acid affects expression EXP 6480464 pirinixic acid affects the expression of F11 mRNA CTD PMID:19136022 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of F11 mRNA CTD PMID:17950772 more ... pirinixic acid multiple interactions EXP 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of F11 mRNA more ... CTD PMID:17950772 more ... raloxifene increases activity ISO RGD:1319673 6480464 Raloxifene Hydrochloride results in increased activity of F11 protein CTD PMID:16359964 SB 431542 multiple interactions ISO RGD:1319673 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of F11 mRNA CTD PMID:27188386 sodium arsenite affects methylation ISO RGD:1319673 6480464 sodium arsenite affects the methylation of F11 gene CTD PMID:28589171 sodium arsenite decreases expression ISO RGD:1319673 6480464 sodium arsenite results in decreased expression of F11 mRNA CTD PMID:29301061 tetrachloroethene decreases expression EXP 6480464 Tetrachloroethylene results in decreased expression of F11 mRNA CTD PMID:28973375 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of F11 mRNA CTD PMID:27339419 tris(2-butoxyethyl) phosphate affects expression ISO RGD:1319673 6480464 tris(2-butoxyethyl) phosphate affects the expression of F11 mRNA CTD PMID:29024780 urethane decreases expression ISO RGD:1319673 6480464 Urethane results in decreased expression of F11 mRNA CTD PMID:28818685 valproic acid decreases expression ISO RGD:1319673 6480464 Valproic Acid results in decreased expression of F11 mRNA CTD PMID:29154799 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of F11 mRNA CTD PMID:24535564 vorinostat multiple interactions ISO RGD:1319673 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of F11 mRNA CTD PMID:27188386
Biological Process blood coagulation ISO UniProtKB:P03951 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 blood coagulation ISO RGD:1309364 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 hemostasis IEA UniProtKB-KW:KW-0356 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 plasminogen activation ISO UniProtKB:P03951 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of fibrinolysis ISO UniProtKB:P03951 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 proteolysis ISO RGD:1309364 2290270 GOC GO_REF:0000096, MGI:MGI:4417868 regulation of blood coagulation IMP MGI:MGI:2384015 2290270 MGI MGI:MGI:3719506 , PMID:16533887 Cellular Component extracellular region IEA UniProtKB-KW:KW-0964 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 extracellular region IEA InterPro:IPR000177 2290270 UniProtKB GO_REF:0000002, MGI:MGI:2152098 extracellular space ISO UniProtKB:P03951 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 extracellular space ISO RGD:1309364 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 Molecular Function heparin binding IEA UniProtKB-KW:KW-0358 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 hydrolase activity IEA UniProtKB-KW:KW-0378 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 identical protein binding ISO UniProtKB:P03951 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 peptidase activity IEA UniProtKB-KW:KW-0645 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 serine-type aminopeptidase activity ISO RGD:1309364 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 serine-type endopeptidase activity IEA InterPro:IPR001254 more ... 2290270 UniProtKB GO_REF:0000002, MGI:MGI:2152098 serine-type peptidase activity IEA UniProtKB-KW:KW-0720 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194
Gene-Chemical Interaction Annotations
