Tmem192 (transmembrane protein 192) - Rat Genome Database
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Gene: Tmem192 (transmembrane protein 192) Mus musculus
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Symbol: Tmem192
Name: transmembrane protein 192
RGD ID: 1319636
MGI Page MGI
Description: Predicted to have protein homodimerization activity. Predicted to localize to several cellular components, including late endosome; lysosomal membrane; and perinuclear region of cytoplasm. Orthologous to human TMEM192 (transmembrane protein 192); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3110005G23Rik
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39865,399,801 - 65,421,688 (+)NCBIGRCm39mm39
GRCm38864,947,149 - 64,969,036 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl864,947,185 - 64,969,033 (+)EnsemblGRCm38mm10GRCm38
MGSCv37867,471,084 - 67,492,935 (+)NCBIGRCm37mm9NCBIm37
MGSCv36867,876,174 - 67,898,022 (+)NCBImm8
Celera867,509,201 - 67,530,946 (+)NCBICelera
Cytogenetic Map8B3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:18799693   PMID:21267068   PMID:21873635   PMID:28504966  


Genomics

Comparative Map Data
Tmem192
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39865,399,801 - 65,421,688 (+)NCBIGRCm39mm39
GRCm38864,947,149 - 64,969,036 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl864,947,185 - 64,969,033 (+)EnsemblGRCm38mm10GRCm38
MGSCv37867,471,084 - 67,492,935 (+)NCBIGRCm37mm9NCBIm37
MGSCv36867,876,174 - 67,898,022 (+)NCBImm8
Celera867,509,201 - 67,530,946 (+)NCBICelera
Cytogenetic Map8B3.1NCBI
TMEM192
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl4165,070,608 - 165,208,549 (-)EnsemblGRCh38hg38GRCh38
GRCh384165,070,608 - 165,112,913 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh374165,997,230 - 166,034,024 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364166,216,680 - 166,253,474 (-)NCBINCBI36hg18NCBI36
Celera4163,328,647 - 163,365,196 (-)NCBI
Cytogenetic Map4q32.3NCBI
HuRef4161,750,449 - 161,784,815 (-)NCBIHuRef
CHM1_14165,973,696 - 166,010,477 (-)NCBICHM1_1
Tmem192
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01626,620,525 - 26,642,537 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1626,619,598 - 26,633,796 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01626,503,237 - 26,515,689 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41626,481,058 - 26,494,314 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11626,481,056 - 26,494,312 (-)NCBI
Celera1624,825,265 - 24,846,005 (-)NCBICelera
Cytogenetic Map16p13NCBI
Tmem192
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540340,199,850 - 40,212,765 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540340,202,180 - 40,211,747 (+)NCBIChiLan1.0ChiLan1.0
TMEM192
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14169,320,974 - 169,352,166 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4169,318,179 - 169,427,945 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04157,269,816 - 157,304,743 (-)NCBIMhudiblu_PPA_v0panPan3
TMEM192
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1561,090,399 - 61,110,762 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11561,088,944 - 61,110,426 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Tmem192
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936555855,096 - 891,525 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM192
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl843,960,724 - 43,990,093 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1843,960,670 - 43,994,286 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2845,924,110 - 45,944,995 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM192
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17111,440,985 - 111,472,196 (-)NCBI
ChlSab1.1 Ensembl7111,443,197 - 111,472,123 (-)Ensembl
Tmem192
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475811,887,968 - 11,900,581 (+)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81472316071045600Mouse
1357811Orq3_movulation rate QTL 3 (mouse)Not determined83201654471287993Mouse
4141437W10q14_mweight 10 weeks QTL 14 (mouse)Not determined3201654471287993Mouse
4141172W6q9_mweight 6 weeks QTL 9 (mouse)Not determined3201654471287993Mouse
4140966Egq12_mearly growth QTL 12 (mouse)Not determined3201654471287993Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1301936Trigq2_mtriglyceride QTL 2 (mouse)Not determined83383736267837502Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84429488078295025Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84763703081637146Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84763703081637146Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84773713481737254Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84879293982793021Mouse
14746987Manh64_mmandible shape 64 (mouse)85005330684053306Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85005330684053306Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:340
Count of miRNA genes:162
Interacting mature miRNAs:167
Transcripts:ENSMUST00000026595, ENSMUST00000079896
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001163747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_028427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001778479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC099723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI849438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC020157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000026595   ⟹   ENSMUSP00000026595
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl864,947,185 - 64,969,033 (+)Ensembl
RefSeq Acc Id: ENSMUST00000079896   ⟹   ENSMUSP00000078819
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl864,947,254 - 64,969,031 (+)Ensembl
RefSeq Acc Id: ENSMUST00000209852   ⟹   ENSMUSP00000147788
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl864,947,219 - 64,966,720 (+)Ensembl
RefSeq Acc Id: ENSMUST00000209923   ⟹   ENSMUSP00000148175
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl864,947,232 - 64,968,903 (+)Ensembl
RefSeq Acc Id: ENSMUST00000211405   ⟹   ENSMUSP00000147585
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl864,959,543 - 64,965,591 (+)Ensembl
RefSeq Acc Id: NM_001163747   ⟹   NP_001157219
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39865,399,837 - 65,421,688 (+)NCBI
GRCm38864,947,185 - 64,969,036 (+)NCBI
MGSCv37867,471,084 - 67,492,935 (+)RGD
Celera867,509,201 - 67,530,946 (+)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_028427   ⟹   NP_082703
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39865,399,837 - 65,421,688 (+)NCBI
GRCm38864,947,185 - 64,969,036 (+)NCBI
MGSCv37867,471,084 - 67,492,935 (+)RGD
Celera867,509,201 - 67,530,946 (+)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XR_001778479
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39865,399,801 - 65,421,688 (+)NCBI
GRCm38864,947,149 - 64,969,036 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_082703   ⟸   NM_028427
- Peptide Label: isoform 1
- UniProtKB: Q9CXT7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001157219   ⟸   NM_001163747
- Peptide Label: isoform 2
- UniProtKB: Q9CXT7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000078819   ⟸   ENSMUST00000079896
RefSeq Acc Id: ENSMUSP00000026595   ⟸   ENSMUST00000026595
RefSeq Acc Id: ENSMUSP00000147585   ⟸   ENSMUST00000211405
RefSeq Acc Id: ENSMUSP00000147788   ⟸   ENSMUST00000209852
RefSeq Acc Id: ENSMUSP00000148175   ⟸   ENSMUST00000209923

Promoters
RGD ID:8667173
Promoter ID:EPDNEW_M11618
Type:initiation region
Name:Tmem192_1
Description:Mus musculus transmembrane protein 192 , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38864,947,221 - 64,947,281EPDNEW
RGD ID:6843823
Promoter ID:MM_KWN:54538
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001163747,   NM_028427
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36867,471,054 - 67,471,554 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1920317 AgrOrtholog
Ensembl Genes ENSMUSG00000025521 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000026595 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000078819 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000147585 UniProtKB/TrEMBL
  ENSMUSP00000147788 UniProtKB/TrEMBL
  ENSMUSP00000148175 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000026595 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000079896 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000209852 UniProtKB/TrEMBL
  ENSMUST00000209923 UniProtKB/TrEMBL
  ENSMUST00000211405 UniProtKB/TrEMBL
InterPro TMEM192 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:73067 UniProtKB/Swiss-Prot
MGD MGI:1920317 ENTREZGENE
NCBI Gene 73067 ENTREZGENE
PANTHER PTHR31592 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TMEM192 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tmem192 PhenoGen
UniGene Mm.294445 ENTREZGENE
UniProt A0A1B0GRM5_MOUSE UniProtKB/TrEMBL
  A0A1B0GS44_MOUSE UniProtKB/TrEMBL
  A0A1B0GT30_MOUSE UniProtKB/TrEMBL
  Q3V186_MOUSE UniProtKB/TrEMBL
  Q9CXT7 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q3THT5 UniProtKB/Swiss-Prot
  Q8VDU8 UniProtKB/Swiss-Prot