Wbp2nl (WBP2 N-terminal like) - Rat Genome Database

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Gene: Wbp2nl (WBP2 N-terminal like) Mus musculus
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Symbol: Wbp2nl
Name: WBP2 N-terminal like
RGD ID: 1319631
MGI Page MGI
Description: Predicted to enable WW domain binding activity; chromatin DNA binding activity; and transcription coactivator activity. Predicted to be involved in egg activation; male pronucleus assembly; and positive regulation of DNA-templated transcription. Predicted to act upstream of or within female pronucleus assembly. Predicted to be located in perinuclear theca; sperm flagellum; and sperm head. Predicted to be active in nucleus. Orthologous to human WBP2NL (WBP2 N-terminal like).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 4930521I23Rik; P; PAWP; postacrosomal sheath WW domain-binding protein; WW domain-binding protein 2-like
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391582,183,126 - 82,198,848 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1582,183,155 - 82,198,824 (+)EnsemblGRCm39 Ensembl
GRCm381582,298,925 - 82,314,647 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1582,298,954 - 82,314,623 (+)EnsemblGRCm38mm10GRCm38
MGSCv371582,129,414 - 82,144,988 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361582,126,719 - 82,142,107 (+)NCBIMGSCv36mm8
Celera1584,423,079 - 84,438,650 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1538.56NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA)
perinuclear theca  (ISS)
sperm flagellum  (IEA,ISO)
sperm head  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:17289678   PMID:17988661   PMID:21677750   PMID:21873635  
PMID:24381051   PMID:24970390   PMID:25057041   PMID:26377222   PMID:38355793  


Genomics

Comparative Map Data
Wbp2nl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391582,183,126 - 82,198,848 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1582,183,155 - 82,198,824 (+)EnsemblGRCm39 Ensembl
GRCm381582,298,925 - 82,314,647 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1582,298,954 - 82,314,623 (+)EnsemblGRCm38mm10GRCm38
MGSCv371582,129,414 - 82,144,988 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361582,126,719 - 82,142,107 (+)NCBIMGSCv36mm8
Celera1584,423,079 - 84,438,650 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1538.56NCBI
WBP2NL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382241,998,788 - 42,058,371 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2241,998,725 - 42,058,456 (+)EnsemblGRCh38hg38GRCh38
GRCh372242,394,792 - 42,424,479 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362240,724,738 - 40,754,425 (+)NCBINCBI36Build 36hg18NCBI36
Celera2226,200,953 - 26,230,676 (+)NCBICelera
Cytogenetic Map22q13.2NCBI
HuRef2225,360,930 - 25,390,655 (+)NCBIHuRef
CHM1_12242,354,919 - 42,384,632 (+)NCBICHM1_1
T2T-CHM13v2.02242,478,395 - 42,537,955 (+)NCBIT2T-CHM13v2.0
Wbp2nl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87115,694,910 - 115,710,912 (+)NCBIGRCr8
mRatBN7.27113,814,793 - 113,831,974 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7113,814,992 - 113,831,333 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.07123,531,657 - 123,548,574 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7123,531,682 - 123,548,081 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07123,516,366 - 123,533,289 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47120,674,629 - 120,689,938 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7110,129,903 - 110,146,820 (+)NCBICelera
Cytogenetic Map7q34NCBI
Wbp2nl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541327,402,545 - 27,436,906 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541327,402,614 - 27,442,106 (+)NCBIChiLan1.0ChiLan1.0
WBP2NL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22351,828,365 - 51,863,810 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12254,527,569 - 54,561,839 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02222,891,166 - 22,926,920 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12240,974,715 - 41,008,296 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2240,974,715 - 41,004,007 (+)Ensemblpanpan1.1panPan2
WBP2NL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11023,333,420 - 23,368,234 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1023,344,094 - 23,368,153 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1023,267,499 - 23,302,315 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01024,077,925 - 24,112,940 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1024,088,813 - 24,112,859 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11023,795,297 - 23,830,271 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01024,116,424 - 24,151,255 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01024,290,357 - 24,325,371 (-)NCBIUU_Cfam_GSD_1.0
LOC101960563
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049456,999,791 - 7,000,591 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493649210,208 - 13,477 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WBP2NL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11924,533,727 - 24,573,482 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1924,554,895 - 24,567,023 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045100,834,032 - 100,875,955 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wbp2nl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247526,711,843 - 6,736,018 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247526,689,501 - 6,736,053 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Wbp2nl
553 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:86
Count of miRNA genes:80
Interacting mature miRNAs:86
Transcripts:ENSMUST00000023089
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
38501067Tip3_mtuberculosis immunophenotype 3, IFN-g level (mouse)155356339689584203Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
4142198Hbtq_mhabituation QTL (mouse)Not determined155116070885160833Mouse
15092079Igly6_mIgG glycosylation 6, GP6 (mouse)157410054082674156Mouse
1357407Pfat4_mpredicted fat percentage 4 (mouse)8.6Body fat amountpredicted fat percentage155711700591117153Mouse
14928306Manh79_mmandible shape 79 (mouse)1578847557104073951Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578601103102901704Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
1302080Szs13_mseizure susceptibility 13 (mouse)Not determined155168583285694449Mouse
1300800Ses3_msalmonella enteritidis susceptibility 3 (mouse)Not determined155711700591117153Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78601103102901704Mouse
13504731Cath5_mcarotid atherosclerosis 5 (mouse)155478912988789129Mouse
15092080Igly7_mIgG glycosylation 7, GP10 (mouse)157779491982674156Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
10045637Heal27_mwound healing/regeneration 29 (mouse)Not determined155141836185418511Mouse
27095936Ulnl4_mulna length 4, 5 week (mouse)155676339687684201Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
1301708Cocrb14_mcocaine related behavior 14 (mouse)Not determined155180651585806651Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1578897881104073951Mouse
12880420V25Dq8_mvitamin D inactive form serum level QTL 8 (mouse)156158420095584200Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577527592104073951Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579163411104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
1301429Pcir3_mperiosteal circumference 3 (mouse)Not determined154846536282465496Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154216339695497881Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
4141902Cia37_mcollagen induced arthritis 37 (mouse)Not determined1580884933104073951Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156316390397163995Mouse
1301472Pain1_mpain 1 (mouse)Not determined157532084690813185Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
27226729Tibmd2_mtibia midshaft diameter 2, 5 week (mouse)153800024486684201Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined79908940104073951Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
1301284Cosz3_mcocaine seizure 3 (mouse)Not determined1580313634104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
10412067Pain2_mpain 2 (mouse)Not determined155164533985645626Mouse
1300974Pgia9_mproteoglycan induced arthritis 9 (mouse)Not determined1580884933104073951Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000023089   ⟹   ENSMUSP00000023089
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1582,183,155 - 82,198,824 (+)Ensembl
GRCm38.p6 Ensembl1582,298,954 - 82,314,623 (+)Ensembl
RefSeq Acc Id: NM_029066   ⟹   NP_083342
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391582,183,185 - 82,198,759 (+)NCBI
GRCm381582,298,984 - 82,314,558 (+)NCBI
MGSCv371582,129,414 - 82,144,988 (+)RGD
Celera1584,423,079 - 84,438,650 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017316772   ⟹   XP_017172261
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391582,183,126 - 82,198,848 (+)NCBI
GRCm381582,298,925 - 82,314,647 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_083342 (Get FASTA)   NCBI Sequence Viewer  
  XP_017172261 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI19521 (Get FASTA)   NCBI Sequence Viewer  
  BAB30005 (Get FASTA)   NCBI Sequence Viewer  
  EDL04517 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000023089
  ENSMUSP00000023089.4
GenBank Protein Q9D529 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_083342   ⟸   NM_029066
- UniProtKB: Q9D529 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017172261   ⟸   XM_017316772
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000023089   ⟸   ENSMUST00000023089
Protein Domains
GRAM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D529-F1-model_v2 AlphaFold Q9D529 1-359 view protein structure

Promoters
RGD ID:8684504
Promoter ID:EPDNEW_M20283
Type:multiple initiation site
Name:Wbp2nl_1
Description:Mus musculus WBP2 N-terminal like , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381582,298,954 - 82,299,014EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1921966 AgrOrtholog
Ensembl Genes ENSMUSG00000022455 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000023089 ENTREZGENE
  ENSMUST00000023089.5 UniProtKB/Swiss-Prot
InterPro GRAM UniProtKB/Swiss-Prot
  WBP2-like UniProtKB/Swiss-Prot
KEGG Report mmu:74716 UniProtKB/Swiss-Prot
MGD MGI:1921966 ENTREZGENE
NCBI Gene 74716 ENTREZGENE
PANTHER PTHR31606 UniProtKB/Swiss-Prot
  PTHR31606:SF2 UniProtKB/Swiss-Prot
Pfam GRAM UniProtKB/Swiss-Prot
PhenoGen Wbp2nl PhenoGen
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot
UniProt Q9D529 ENTREZGENE, UniProtKB/Swiss-Prot