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Gene: Spry1 (sprouty RTK signaling antagonist 1) Mus musculus
Symbol: Spry1
Name: sprouty RTK signaling antagonist 1
Description: Involved in several processes, including animal organ development; establishment of mitotic spindle orientation; and negative regulation of signal transduction. Predicted to localize to the Golgi apparatus; cytosol; and nucleoplasm. Is expressed in several structures, including alimentary system; brain; future brain; limb; and sensory organ. Orthologous to human SPRY1 (sprouty RTK signaling antagonist 1); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 4-hydroxynon-2-enal.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: inhibitor of receptor tyrosine kinases; protein sprouty homolog 1; sprouty 1; sprouty homolog 1; sprouty homolog 1 (Drosophila); sprouty1; spry-1
Homo sapiens (human) : SPRY1 (sprouty RTK signaling antagonist 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Spry1 (sprouty RTK signaling antagonist 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spry1 (sprouty RTK signaling antagonist 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SPRY1 (sprouty RTK signaling antagonist 1)
Canis lupus familiaris (dog) : SPRY1 (sprouty RTK signaling antagonist 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spry1 (sprouty RTK signaling antagonist 1)
Sus scrofa (pig) : SPRY1 (sprouty RTK signaling antagonist 1)
Chlorocebus sabaeus (green monkey) : SPRY1 (sprouty RTK signaling antagonist 1)
Heterocephalus glaber (naked mole-rat) : Spry1 (sprouty RTK signaling antagonist 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl337,639,947 - 37,644,598 (+)Ensembl
GRCm38337,639,291 - 37,644,599 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37337,538,872 - 37,543,521 (+)NCBIGRCm37mm9NCBIm37
MGSCv36337,831,525 - 37,836,146 (+)NCBImm8
Celera337,514,171 - 37,518,800 (+)NCBICelera
Cytogenetic Map3 BNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Spry1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319562
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.