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Gene: NTHL1 (nth like DNA glycosylase 1) Homo sapiens
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Symbol: NTHL1
Name: nth like DNA glycosylase 1
Description: The protein encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity. [provided by RefSeq, Oct 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bifunctional DNA N-glycoslyase/DNA-(apurinic or apyrimidinic site) lyase; bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase; DNA glycoslyase/AP lyase; DNA glycosylase/AP lyase; endonuclease III-like protein 1; FAP3; hNTH1; nth endonuclease III-like 1; nth-like DNA glycosylase 1; NTH1; OCTS3
Orthologs:
Mus musculus (house mouse) : Nthl1 (nth (endonuclease III)-like 1 (E.coli))  MGI  Alliance
Rattus norvegicus (Norway rat) : Nthl1 (nth-like DNA glycosylase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nthl1 (nth like DNA glycosylase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NTHL1 (nth like DNA glycosylase 1)
Canis lupus familiaris (dog) : NTHL1 (nth like DNA glycosylase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nthl1 (nth like DNA glycosylase 1)
Sus scrofa (pig) : NTHL1 (nth like DNA glycosylase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,039,815 - 2,047,872 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37162,089,816 - 2,097,931 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,029,817 - 2,037,868 (-)NCBINCBI36hg18NCBI36
Build 34162,029,816 - 2,037,868NCBI
Celera162,301,923 - 2,309,974 (-)NCBI
Cytogenetic Map16p13.3NCBI
HuRef162,014,043 - 2,022,132 (-)NCBIHuRef
CHM1_1162,089,796 - 2,097,845 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NTHL1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319554
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.