Prss44 (protease, serine 44) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Prss44 (protease, serine 44) Mus musculus
Analyze
Symbol: Prss44
Name: protease, serine 44
RGD ID: 1319550
MGI Page MGI
Description: Predicted to have serine-type endopeptidase activity. Predicted to be involved in germ cell development; proteolysis; and spermatogenesis. Localizes to cytoplasm. Orthologous to human PRSS44P (serine protease 44, pseudogene); INTERACTS WITH 1,2-dichloroethane; benzo[a]pyrene; casticin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1700036D21Rik; 79H19A; AU043574; AU043597; protease, serine, 44; serine protease 44; serine protease-like 1; TES; TESSP-4; Tessp4; testis serine protease 4; testis specific serine protease 4; testis-specific serine protease 4
RGD Orthologs
Human
Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399110,642,987 - 110,647,067 (+)NCBIGRCm39mm39
GRCm389110,813,919 - 110,817,999 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9110,813,994 - 110,824,523 (+)EnsemblGRCm38mm10GRCm38
MGSCv379110,716,498 - 110,720,503 (+)NCBIGRCm37mm9NCBIm37
MGSCv369110,658,843 - 110,669,341 (+)NCBImm8
Celera9110,544,865 - 110,548,871 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map960.79NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12140191   PMID:16141072   PMID:16141073   PMID:21677750   PMID:21873635   PMID:23536369   PMID:31403672  


Genomics

Comparative Map Data
Prss44
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399110,642,987 - 110,647,067 (+)NCBIGRCm39mm39
GRCm389110,813,919 - 110,817,999 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9110,813,994 - 110,824,523 (+)EnsemblGRCm38mm10GRCm38
MGSCv379110,716,498 - 110,720,503 (+)NCBIGRCm37mm9NCBIm37
MGSCv369110,658,843 - 110,669,341 (+)NCBImm8
Celera9110,544,865 - 110,548,871 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map960.79NCBI
PRSS44P
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl346,809,359 - 46,812,486 (-)EnsemblGRCh38hg38GRCh38
GRCh38346,808,640 - 46,812,574 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37346,852,688 - 46,854,048 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36346,825,190 - 46,828,980 (-)NCBINCBI36hg18NCBI36
Celera346,789,277 - 46,792,512 (-)NCBI
Cytogenetic Map3p21.31NCBI
HuRef346,895,483 - 46,896,843 (-)NCBIHuRef
CHM1_1346,802,802 - 46,804,162 (-)NCBICHM1_1
Prss44
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08119,083,900 - 119,097,707 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8119,083,900 - 119,097,707 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08118,423,162 - 118,436,016 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48115,196,265 - 115,209,775 (+)NCBIRGSC3.4rn4RGSC3.4
Celera8110,074,270 - 110,087,887 (+)NCBICelera
Cytogenetic Map8q32NCBI

Position Markers
AU043597  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389110,817,707 - 110,817,793UniSTSGRCm38
MGSCv379110,720,211 - 110,720,297UniSTSGRCm37
Celera9110,548,579 - 110,548,665UniSTS
Cytogenetic Map9F3UniSTS
cM Map963.97UniSTS
Whitehead/MRC_RH91128.54UniSTS
AU043574  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389110,817,707 - 110,817,954UniSTSGRCm38
MGSCv379110,720,211 - 110,720,458UniSTSGRCm37
Celera9110,548,579 - 110,548,826UniSTS
Cytogenetic Map9F3UniSTS
cM Map963.97UniSTS
Whitehead/MRC_RH91128.88UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63332429120362868Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63332429120362868Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963332429120362868Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975775364114474379Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975775364114474379Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978640645112640755Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979397810113397888Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981798268115798392Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982910333116910428Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982910333116910428Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982910333116910428Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984528818118528921Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986230401120230530Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986239845120289624Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986748483120748483Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987800000121800000Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989977005118938021Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994981301112872929Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9101060861124595110Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9102000187124595110Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9102000187124595110Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103289445124595110Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103289445124595110Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103289445124595110Mouse
13515058Adip20d_madiposity 20d (mouse)9108915010118915010Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:483
Count of miRNA genes:344
Interacting mature miRNAs:401
Transcripts:ENSMUST00000098345, ENSMUST00000141089
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000098345   ⟹   ENSMUSP00000095948
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9110,813,994 - 110,817,999 (+)Ensembl
RefSeq Acc Id: ENSMUST00000141089   ⟹   ENSMUSP00000117039
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9110,814,027 - 110,824,523 (+)Ensembl
RefSeq Acc Id: ENSMUST00000196597
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9110,815,217 - 110,816,948 (+)Ensembl
RefSeq Acc Id: ENSMUST00000198815
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9110,814,451 - 110,816,529 (+)Ensembl
RefSeq Acc Id: NM_148940   ⟹   NP_683742
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399110,643,062 - 110,647,067 (+)NCBI
GRCm389110,813,994 - 110,817,999 (+)NCBI
MGSCv379110,716,498 - 110,720,503 (+)RGD
Celera9110,544,865 - 110,548,871 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006512313   ⟹   XP_006512376
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399110,642,987 - 110,647,067 (+)NCBI
GRCm389110,813,919 - 110,817,999 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006512314   ⟹   XP_006512377
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399110,642,992 - 110,647,067 (+)NCBI
GRCm389110,813,924 - 110,817,999 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006512317   ⟹   XP_006512380
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399110,643,095 - 110,647,067 (+)NCBI
GRCm389110,814,027 - 110,817,999 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017313617   ⟹   XP_017169106
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399110,642,992 - 110,645,578 (+)NCBI
GRCm389110,813,924 - 110,816,510 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030244649   ⟹   XP_030100509
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399110,643,457 - 110,647,067 (+)NCBI
GRCm389110,814,389 - 110,817,999 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_683742   ⟸   NM_148940
- Peptide Label: precursor
- UniProtKB: Q402U7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006512377   ⟸   XM_006512314
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006512380   ⟸   XM_006512317
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006512376   ⟸   XM_006512313
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017169106   ⟸   XM_017313617
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_030100509   ⟸   XM_030244649
- Peptide Label: isoform X4
RefSeq Acc Id: ENSMUSP00000095948   ⟸   ENSMUST00000098345
RefSeq Acc Id: ENSMUSP00000117039   ⟸   ENSMUST00000141089
Protein Domains
Peptidase S1

Promoters
RGD ID:8671024
Promoter ID:EPDNEW_M13543
Type:single initiation site
Name:Prss44_1
Description:Mus musculus protease, serine 44 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389110,814,012 - 110,814,072EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1920586 AgrOrtholog
Ensembl Genes ENSMUSG00000032493 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000095948 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000117039 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000098345 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000141089 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Peptidase_S1_PA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/Swiss-Prot
  Trypsin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/Swiss-Prot
  TRYPSIN_SER UniProtKB/Swiss-Prot
KEGG Report mmu:73336 UniProtKB/Swiss-Prot
MGD MGI:1920586 ENTREZGENE
NCBI Gene 73336 ENTREZGENE
Pfam Trypsin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Prss44 PhenoGen
PRINTS CHYMOTRYPSIN UniProtKB/Swiss-Prot
PROSITE TRYPSIN_DOM UniProtKB/Swiss-Prot
  TRYPSIN_HIS UniProtKB/Swiss-Prot
  TRYPSIN_SER UniProtKB/Swiss-Prot
SMART Tryp_SPc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50494 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.200587 ENTREZGENE
UniProt K7E6F0_MOUSE UniProtKB/TrEMBL
  PRS44_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q924U6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-26 Prss44  protease, serine 44    protease, serine, 44  Symbol and/or name change 5135510 APPROVED
2011-07-27 Prss44  protease, serine, 44  1700036D21Rik  RIKEN cDNA 1700036D21 gene  Symbol and/or name change 5135510 APPROVED