Gene: KCNV2 (potassium voltage-gated channel modifier subfamily V member 2) Homo sapiens
Symbol: KCNV2
Name: potassium voltage-gated channel modifier subfamily V member 2
Description: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: KV11.1; Kv8.2; MGC120515; OTTHUMP00000020986; potassium channel, subfamily V, member 2; potassium channel, voltage gated modifier subfamily V, member 2; potassium voltage-gated channel subfamily V member 2; RCD3B; voltage-gated potassium channel Kv8.2; voltage-gated potassium channel subunit Kv8.2
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3892,717,526 - 2,730,037 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3792,717,526 - 2,730,037 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3692,707,526 - 2,719,757 (+)NCBINCBI36hg18NCBI36
Build 3492,707,525 - 2,719,757NCBI
Celera92,635,779 - 2,648,010 (+)NCBI
Cytogenetic Map9p24.2NCBI
HuRef92,672,590 - 2,685,127 (+)NCBIHuRef
CHM1_192,717,855 - 2,730,366 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KCNV2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319524
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2018-03-13
Status: ACTIVE