Eif1b (eukaryotic translation initiation factor 1B) - Rat Genome Database
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Gene: Eif1b (eukaryotic translation initiation factor 1B) Mus musculus
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Symbol: Eif1b
Name: eukaryotic translation initiation factor 1B
RGD ID: 1319472
MGI Page MGI
Description: Predicted to have ribosomal small subunit binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to localize to eukaryotic 43S preinitiation complex. Is expressed in cortical plate; embryo; olfactory cortex ventricular layer; telencephalon mantle layer; and telencephalon ventricular layer. Orthologous to human EIF1B (eukaryotic translation initiation factor 1B); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1500010M16Rik; 3110001N14Rik; Gc20; translation factor sui1 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399120,321,672 - 120,324,393 (+)NCBIGRCm39mm39
GRCm389120,492,606 - 120,495,327 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9120,492,232 - 120,495,330 (+)EnsemblGRCm38mm10GRCm38
MGSCv379120,401,724 - 120,404,445 (+)NCBIGRCm37mm9NCBIm37
MGSCv369120,341,339 - 120,344,025 (+)NCBImm8
Celera9120,962,066 - 120,964,791 (+)NCBICelera
Cytogenetic Map9F4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10725249   PMID:11042159   PMID:11076861   PMID:12477932   PMID:15489334   PMID:16141072   PMID:16141073   PMID:18055048   PMID:21267068   PMID:21873635  
PMID:24194600   PMID:30196744   PMID:30680919   PMID:31097699  


Genomics

Comparative Map Data
Eif1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399120,321,672 - 120,324,393 (+)NCBIGRCm39mm39
GRCm389120,492,606 - 120,495,327 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9120,492,232 - 120,495,330 (+)EnsemblGRCm38mm10GRCm38
MGSCv379120,401,724 - 120,404,445 (+)NCBIGRCm37mm9NCBIm37
MGSCv369120,341,339 - 120,344,025 (+)NCBImm8
Celera9120,962,066 - 120,964,791 (+)NCBICelera
Cytogenetic Map9F4NCBI
EIF1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl340,309,707 - 40,312,424 (+)EnsemblGRCh38hg38GRCh38
GRCh38340,309,707 - 40,312,424 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37340,351,173 - 40,353,915 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36340,326,177 - 40,328,919 (+)NCBINCBI36hg18NCBI36
Celera340,293,858 - 40,296,600 (+)NCBI
Cytogenetic Map3p22.1NCBI
HuRef340,395,243 - 40,397,984 (+)NCBIHuRef
CHM1_1340,301,070 - 40,303,813 (+)NCBICHM1_1
Eif1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08129,158,112 - 129,160,726 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8129,158,103 - 129,160,757 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08128,356,696 - 128,359,310 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48125,499,378 - 125,501,992 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18125,519,015 - 125,521,753 (+)NCBI
Celera8119,345,651 - 119,348,265 (+)NCBICelera
Cytogenetic Map8q32NCBI
Eif1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542029,514,067 - 29,515,363 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542029,514,067 - 29,515,362 (-)NCBIChiLan1.0ChiLan1.0
EIF1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1340,484,768 - 40,487,517 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl340,484,768 - 40,487,517 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0340,213,113 - 40,215,844 (+)NCBIMhudiblu_PPA_v0panPan3
EIF1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl239,798,232 - 9,800,700 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1239,798,141 - 9,800,976 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Eif1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493647329,290,460 - 29,292,968 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EIF1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1324,574,910 - 24,577,616 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11324,575,183 - 24,577,486 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21326,926,936 - 26,932,666 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EIF1B
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1221,806,431 - 1,809,180 (+)NCBI
ChlSab1.1 Ensembl221,806,396 - 1,809,466 (+)Ensembl
Eif1b
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473078,361,181 - 78,363,333 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11251716Siim2_mstress induced immobility 2 (mouse)986748483120748483Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987800000121800000Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9101060861124595110Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9102000187124595110Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9102000187124595110Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103289445124595110Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103289445124595110Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103289445124595110Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:115
Count of miRNA genes:110
Interacting mature miRNAs:114
Transcripts:ENSMUST00000007139
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000007139   ⟹   ENSMUSP00000007139
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9120,492,491 - 120,495,330 (+)Ensembl
RefSeq Acc Id: ENSMUST00000217553   ⟹   ENSMUSP00000149825
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9120,492,232 - 120,494,640 (+)Ensembl
RefSeq Acc Id: NM_026892   ⟹   NP_081168
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399120,321,672 - 120,324,393 (+)NCBI
GRCm389120,492,606 - 120,495,327 (+)ENTREZGENE
MGSCv379120,401,724 - 120,404,445 (+)RGD
Celera9120,962,066 - 120,964,791 (+)RGD
cM Map9 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_081168   ⟸   NM_026892
- UniProtKB: Q9CXU9 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000007139   ⟸   ENSMUST00000007139
RefSeq Acc Id: ENSMUSP00000149825   ⟸   ENSMUST00000217553
Protein Domains
SUI1

Promoters
RGD ID:6844405
Promoter ID:MM_KWN:59173
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:AK085969_D830035M03RIK,   NM_026892
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv369120,401,646 - 120,402,392 (-)MPROMDB
RGD ID:8671230
Promoter ID:EPDNEW_M13646
Type:initiation region
Name:Eif1b_1
Description:Mus musculus eukaryotic translation initiation factor 1B , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389120,492,633 - 120,492,693EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1916219 AgrOrtholog
Ensembl Genes ENSMUSG00000006941 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000007139 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000149825 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000007139 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000217553 UniProtKB/TrEMBL
InterPro SUI1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUI1_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUI1_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:68969 UniProtKB/Swiss-Prot
MGD MGI:1916219 ENTREZGENE
NCBI Gene 68969 ENTREZGENE
Pfam SUI1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Eif1b PhenoGen
PIRSF SUI1_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SUI1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF55159 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs SUI1_MOF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.28753 ENTREZGENE
UniProt A0A1L1SSA3_MOUSE UniProtKB/TrEMBL
  EIF1B_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE