Agpat2 (1-acylglycerol-3-phosphate O-acyltransferase 2) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Agpat2 (1-acylglycerol-3-phosphate O-acyltransferase 2) Mus musculus
Analyze
Symbol: Agpat2
Name: 1-acylglycerol-3-phosphate O-acyltransferase 2
RGD ID: 1319454
MGI Page MGI
Description: Enables 1-acylglycerol-3-phosphate O-acyltransferase activity. Involved in triglyceride biosynthetic process. Located in endoplasmic reticulum. Is active in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and urinary system. Used to study congenital generalized lipodystrophy type 1. Human ortholog(s) of this gene implicated in congenital generalized lipodystrophy type 1 and lipodystrophy. Orthologous to human AGPAT2 (1-acylglycerol-3-phosphate O-acyltransferase 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1-acyl-sn-glycerol-3-phosphate acyltransferase beta; 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta); 1-AGP acyltransferase 2; 1-AGPAT 2; 2510002J07Rik; AV000834; BSC; BSCL; BSCL1; LPAAB; LPAAT; LPAAT-beta; lysophosphatidic acid acyltransferase beta
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39226,483,069 - 26,494,429 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl226,483,069 - 26,494,429 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38226,593,057 - 26,604,417 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl226,593,057 - 26,604,417 (-)Ensemblmm10GRCm38
MGSCv37226,449,107 - 26,459,730 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36226,415,596 - 26,426,219 (-)NCBIMGSCv36mm8
Celera226,310,673 - 26,321,538 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map218.96NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2-hydroxypropanoic acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
4,4'-sulfonyldiphenol  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
alpha-Zearalanol  (ISO)
amitrole  (ISO)
amphetamine  (ISO)
anandamide  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
bisphenol A  (ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
butan-1-ol  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
capecitabine  (ISO)
carbendazim  (EXP)
carbon nanotube  (EXP)
chlorpyrifos  (EXP,ISO)
ciglitazone  (EXP)
cisplatin  (ISO)
clofibric acid  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
diethylstilbestrol  (ISO)
dorsomorphin  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP,ISO)
fenthion  (EXP)
flutamide  (ISO)
gemcitabine  (ISO)
genistein  (ISO)
gentamycin  (ISO)
GW 4064  (ISO)
GW 7647  (ISO)
hexadecanoic acid  (ISO)
hydralazine  (ISO)
indometacin  (ISO)
inulin  (EXP)
lidocaine  (ISO)
lipopolysaccharide  (EXP)
methimazole  (ISO)
O-methyleugenol  (ISO)
obeticholic acid  (ISO)
oleic acid  (ISO)
paracetamol  (EXP,ISO)
parathion  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP,ISO)
pirinixic acid  (EXP)
propiconazole  (EXP)
rac-lactic acid  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
Soman  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
tetracycline  (EXP)
titanium dioxide  (EXP)
tributylstannane  (EXP)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
endoplasmic reticulum  (IBA,IDA,IEA,ISO)
endoplasmic reticulum membrane  (IDA,IEA,TAS)
membrane  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal abdominal fat pad morphology  (IAGP)
abnormal brown adipose tissue morphology  (IAGP)
abnormal dentin development  (IAGP)
abnormal fatty acids level  (IAGP)
abnormal gas homeostasis  (IAGP)
abnormal glucose homeostasis  (IAGP)
abnormal incisor morphology  (IAGP)
abnormal kidney morphology  (IEA)
abnormal lipid homeostasis  (IAGP)
abnormal liver morphology  (IAGP)
abnormal phospholipid level  (IAGP)
abnormal small intestine morphology  (IAGP)
abnormal spleen morphology  (IEA)
abnormal stomach morphology  (IEA)
abnormal testis morphology  (IEA)
abnormal uterus morphology  (IEA)
abnormal vertebral arch morphology  (IEA)
abnormal white fat cell morphology  (IAGP)
absent subcutaneous adipose tissue  (IAGP)
adipose tissue necrosis  (IAGP)
ameloblast degeneration  (IAGP)
brown adipose tissue inflammation  (IAGP)
decreased body size  (IAGP)
decreased body temperature  (IAGP)
decreased body weight  (IAGP)
decreased brown adipose tissue amount  (IAGP)
decreased circulating free fatty acids level  (IAGP)
decreased circulating leptin level  (IAGP)
decreased locomotor activity  (IAGP)
decreased percent body fat/body weight  (IAGP)
decreased respiratory quotient  (IAGP)
decreased survivor rate  (IAGP)
decreased total body fat amount  (IAGP)
decreased white adipose tissue amount  (IAGP)
decreased white fat cell number  (IAGP)
decreased white fat cell size  (IAGP)
distended abdomen  (IAGP)
enlarged kidney  (IEA)
enlarged liver  (IAGP)
enlarged pancreatic islets  (IAGP)
enlarged spleen  (IEA)
enlarged stomach  (IEA)
enlarged uterus  (IEA)
femur fracture  (IAGP)
granulomatous inflammation  (IAGP)
hepatic steatosis  (IAGP)
hyperglycemia  (IAGP)
improved glucose tolerance  (IAGP)
increased carbon dioxide production  (IAGP)
increased circulating cholesterol level  (IAGP)
increased circulating glucose level  (IAGP)
increased circulating insulin level  (IAGP)
increased circulating serum albumin level  (IEA)
increased circulating total protein level  (IEA)
increased circulating triglyceride level  (IAGP)
increased fluid intake  (IAGP)
increased food intake  (IAGP)
increased kidney weight  (IAGP)
increased liver triglyceride level  (IAGP)
increased liver weight  (IAGP)
increased oxygen consumption  (IAGP)
increased pancreatic beta cell mass  (IAGP)
increased pancreatic beta cell number  (IAGP)
increased spleen weight  (IAGP)
insulin resistance  (IAGP)
lipodystrophy  (IAGP)
liver inflammation  (IAGP)
microvesicular hepatic steatosis  (IAGP)
no spontaneous movement  (IEA)
pale liver  (IAGP)
polydipsia  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
preweaning lethality, complete penetrance  (IEA)
reduced enamel thickness  (IAGP)
rough coat  (IAGP)
small testis  (IEA)
References

References - curated
# Reference Title Reference Citation
1. AGPAT2 is mutated in congenital generalized lipodystrophy linked to chromosome 9q34. Agarwal AK, etal., Nat Genet. 2002 May;31(1):21-3. Epub 2002 Apr 22.
2. Molecular mechanisms of hepatic steatosis and insulin resistance in the AGPAT2-deficient mouse model of congenital generalized lipodystrophy. Cortes VA, etal., Cell Metab. 2009 Feb;9(2):165-76. doi: 10.1016/j.cmet.2009.01.002.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12765973   PMID:14610273   PMID:14681479   PMID:15367102   PMID:15782199   PMID:16141072   PMID:16141073  
PMID:16150824   PMID:16449762   PMID:16495223   PMID:21051554   PMID:21267068   PMID:21873635   PMID:21873652   PMID:22872237   PMID:24293639   PMID:24425876   PMID:26417690   PMID:26508642  
PMID:26880786   PMID:27408775   PMID:28302796   PMID:33989739   PMID:34824276   PMID:37591406   PMID:37752957   PMID:38274405   PMID:38623324  


Genomics

Comparative Map Data
Agpat2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39226,483,069 - 26,494,429 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl226,483,069 - 26,494,429 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38226,593,057 - 26,604,417 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl226,593,057 - 26,604,417 (-)Ensemblmm10GRCm38
MGSCv37226,449,107 - 26,459,730 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36226,415,596 - 26,426,219 (-)NCBIMGSCv36mm8
Celera226,310,673 - 26,321,538 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map218.96NCBI
AGPAT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389136,673,143 - 136,687,457 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9136,673,143 - 136,687,457 (-)Ensemblhg38GRCh38
GRCh379139,567,595 - 139,581,909 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369138,687,416 - 138,701,732 (-)NCBIBuild 36Build 36hg18NCBI36
Build 349136,843,432 - 136,857,712NCBI
Celera9110,081,330 - 110,095,564 (-)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9109,027,535 - 109,041,933 (-)NCBIHuRef
CHM1_19139,716,530 - 139,730,723 (-)NCBICHM1_1
T2T-CHM13v2.09148,906,123 - 148,920,642 (-)NCBIT2T-CHM13v2.0
Agpat2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8329,814,924 - 29,826,569 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl329,814,924 - 29,826,581 (-)EnsemblGRCr8
mRatBN7.239,416,837 - 9,428,567 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl39,416,843 - 9,428,371 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx312,481,959 - 12,492,601 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0321,065,209 - 21,075,851 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0319,320,532 - 19,331,176 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.034,044,741 - 4,055,384 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl34,044,542 - 4,055,806 (-)Ensemblrn6Rnor6.0
Rnor_5.039,404,488 - 9,415,618 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.434,769,863 - 4,781,045 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera34,236,651 - 4,247,224 (-)NCBICelera
RGSC_v3.134,769,881 - 4,809,158 (-)NCBI
Cytogenetic Map3p13NCBI
Agpat2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555134,135,460 - 4,149,677 (+)Ensembl
ChiLan1.0NW_0049555134,142,074 - 4,145,097 (+)NCBIChiLan1.0ChiLan1.0
AGPAT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2112,696,619 - 2,710,862 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan192,699,026 - 2,713,196 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09107,749,195 - 107,763,033 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19136,722,914 - 136,737,286 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9136,722,914 - 136,737,286 (-)EnsemblpanPan2panpan1.1
AGPAT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1948,864,300 - 48,877,627 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl948,864,376 - 48,877,620 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha948,116,305 - 48,129,246 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0949,742,050 - 49,754,989 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl949,742,045 - 49,754,983 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1948,523,198 - 48,536,132 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0948,816,797 - 48,829,729 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0948,864,276 - 48,877,219 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Agpat2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947202,176,086 - 202,203,966 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366691,195,365 - 1,202,042 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366691,185,204 - 1,198,972 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGPAT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.21313,736,965 - 313,740,537 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AGPAT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1121,511,063 - 1,525,146 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl121,511,124 - 1,525,440 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660583,743,355 - 3,757,442 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Agpat2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247601,747,081 - 1,755,113 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247601,746,642 - 1,755,154 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Agpat2
593 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:993
Count of miRNA genes:527
Interacting mature miRNAs:647
Transcripts:ENSMUST00000028286, ENSMUST00000131940, ENSMUST00000140386, ENSMUST00000140508, ENSMUST00000154753
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552706Cia24_mcollagen induced arthritis QTL 24 (mouse)Not determined22467911533523172Mouse
8552707Cia23_mcollagen induced arthritis QTL 23 (mouse)Not determined21212953766556453Mouse
1300624Insq7_minsulin QTL 7 (mouse)Not determined2938444643384575Mouse
8552705Cia25_mcollagen induced arthritis 25 (mouse)Not determined22467911533523172Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
26884438Sklq12_mskull length QTL 12, 16 week (mouse)22459001254890012Mouse
1301790Pcfm1_mperiosteal circumference and femur length 1 (mouse)Not determined2823629642236396Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
4142130Pgis2_mproteoglycan induced spondylitis 2 (mouse)Not determined22530805156971811Mouse
1301980Fcsa5_mfemoral cross-sectional area 5 (mouse)Not determined2767911541679261Mouse
1301376Etohc1_methanol consumption 1 (mouse)Not determined22112972555129871Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
12792980Fbmd1_mfemoral bone mineral density 1, females only (mouse)22503449245034492Mouse
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1301641Sbmd2_mspinal bone mineral density 2 (mouse)Not determined21421456748214713Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
1301838Sluc16_msusceptibility to lung cancer 16 (mouse)Not determined2126529589Mouse
10755513Amzn4_manatomical modifier of Zfp423 4 (mouse)2938444643384575Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
12904743Carcdq3_mcardiac collagen deposition QTL 3 (mouse)2323494028179150Mouse
13463470Tubisq1_mtubulointerstitial injury severity, QTL 1 (mouse)22368914557689269Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
4141708Pbwg1.2_mpostnatal body weight growth 1.2 (mouse)Not determined2112972555129871Mouse
10043876Adip22_madiposity 22 (mouse)Not determined2830805142308240Mouse
12903993Opfaq1_mopen field activity QTL 1 (mouse)2967669127022642Mouse

Markers in Region
AV000834  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38226,593,199 - 26,593,314UniSTSGRCm38
MGSCv37226,448,719 - 26,448,834UniSTSGRCm37
Celera226,310,285 - 26,310,400UniSTS
Cytogenetic Map2A3UniSTS
Whitehead/MRC_RH2453.92UniSTS
D2Mit417  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38226,601,731 - 26,601,853UniSTSGRCm38
MGSCv37226,457,251 - 26,457,373UniSTSGRCm37
Celera226,318,996 - 26,319,120UniSTS
Cytogenetic Map2A3UniSTS
cM Map215.0UniSTS
Whitehead Genetic220.8UniSTS
Whitehead/MRC_RH2453.92UniSTS
Agpat2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2A3UniSTS
cM Map2 UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000028286   ⟹   ENSMUSP00000028286
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl226,483,069 - 26,494,344 (-)Ensembl
GRCm38.p6 Ensembl226,593,057 - 26,604,332 (-)Ensembl
Ensembl Acc Id: ENSMUST00000131940
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl226,483,069 - 26,494,223 (-)Ensembl
GRCm38.p6 Ensembl226,593,057 - 26,604,211 (-)Ensembl
Ensembl Acc Id: ENSMUST00000140386
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl226,484,515 - 26,494,429 (-)Ensembl
GRCm38.p6 Ensembl226,594,503 - 26,604,417 (-)Ensembl
Ensembl Acc Id: ENSMUST00000140508
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl226,486,130 - 26,493,728 (-)Ensembl
GRCm38.p6 Ensembl226,596,118 - 26,603,716 (-)Ensembl
Ensembl Acc Id: ENSMUST00000154753   ⟹   ENSMUSP00000115059
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl226,486,453 - 26,493,938 (-)Ensembl
GRCm38.p6 Ensembl226,596,441 - 26,603,926 (-)Ensembl
RefSeq Acc Id: NM_026212   ⟹   NP_080488
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39226,483,069 - 26,494,429 (-)NCBI
GRCm38226,593,057 - 26,604,417 (-)NCBI
MGSCv37226,449,107 - 26,459,730 (-)RGD
Celera226,310,143 - 26,321,745 (-)NCBI
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017319222   ⟹   XP_017174711
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39226,483,073 - 26,494,366 (-)NCBI
GRCm38226,593,061 - 26,604,287 (-)NCBI
Sequence:
RefSeq Acc Id: NP_080488   ⟸   NM_026212
- Peptide Label: precursor
- UniProtKB: Q8K3K7 (UniProtKB/Swiss-Prot),   Q059U0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017174711   ⟸   XM_017319222
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSMUSP00000028286   ⟸   ENSMUST00000028286
Ensembl Acc Id: ENSMUSP00000115059   ⟸   ENSMUST00000154753
Protein Domains
Phospholipid/glycerol acyltransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8K3K7-F1-model_v2 AlphaFold Q8K3K7 1-278 view protein structure

Promoters
RGD ID:6848736
Promoter ID:MM_TRO:5354
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day3,   3T3L1_Day4,   Brain
Transcripts:MTR004737.2.527.6
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36226,451,509 - 26,452,009 (-)MPROMDB
RGD ID:6848735
Promoter ID:MM_TRO:5355
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:MTR004737.2.527.5
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36226,452,436 - 26,452,936 (-)MPROMDB
RGD ID:6830713
Promoter ID:MM_KWN:28296
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:ENSMUST00000102901,   OTTMUST00000027050,   OTTMUST00000027051,   OTTMUST00000027052,   OTTMUST00000027053,   OTTMUST00000027054
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36226,459,406 - 26,460,587 (-)MPROMDB
RGD ID:6876714
Promoter ID:EPDNEW_M1808
Type:initiation region
Name:Agpat2_1
Description:Mus musculus 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidicacid acyltransferase, beta) , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38226,604,242 - 26,604,302EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1914762 AgrOrtholog
Ensembl Genes ENSMUSG00000026922 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000028286 ENTREZGENE
  ENSMUST00000028286.12 UniProtKB/Swiss-Prot
  ENSMUST00000131940 ENTREZGENE
InterPro AGP_acyltrans UniProtKB/Swiss-Prot
  Plipid/glycerol_acylTrfase UniProtKB/Swiss-Prot
KEGG Report mmu:67512 UniProtKB/Swiss-Prot
MGD MGI:1914762 ENTREZGENE
NCBI Gene 67512 ENTREZGENE
PANTHER 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE UniProtKB/Swiss-Prot
  1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE BETA UniProtKB/Swiss-Prot
Pfam Acyltransferase UniProtKB/Swiss-Prot
PhenoGen Agpat2 PhenoGen
SMART PlsC UniProtKB/Swiss-Prot
Superfamily-SCOP Glycerol-3-phosphate (1)-acyltransferase UniProtKB/Swiss-Prot
UniProt A2AI22_MOUSE UniProtKB/TrEMBL
  PLCB_MOUSE UniProtKB/Swiss-Prot
  Q059U0 ENTREZGENE, UniProtKB/TrEMBL
  Q8K3K7 ENTREZGENE
  Q9CWA8_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-07-04 Agpat2  1-acylglycerol-3-phosphate O-acyltransferase 2  Agpat2  1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)  Symbol and/or name change 5135510 APPROVED