Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SDSL mRNA | CTD | PMID:36331819 | 17beta-estradiol | decreases expression | ISO | Sdsl (Rattus norvegicus) | 6480464 | Estradiol results in decreased expression of SDSL mRNA | CTD | PMID:32145629 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | EXP | | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin binds to AHR protein] which results in decreased expression of SDSL mRNA | CTD | PMID:16214954 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Sdsl (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SDSL mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SDSL mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Sdsl (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SDSL mRNA | CTD | PMID:21215274 | 2,4-dinitrotoluene | affects expression | ISO | Sdsl (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of SDSL mRNA | CTD | PMID:21346803 | 6-propyl-2-thiouracil | decreases expression | ISO | Sdsl (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of SDSL mRNA | CTD | PMID:24780913 | acrylamide | affects expression | ISO | Sdsl (Rattus norvegicus) | 6480464 | Acrylamide affects the expression of SDSL mRNA | CTD | PMID:28959563 | aflatoxin B1 | affects expression | ISO | SDSL (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of SDSL protein | CTD | PMID:20106945 | Aflatoxin B2 alpha | increases methylation | ISO | SDSL (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of SDSL exon | CTD | PMID:30157460 | antirheumatic drug | decreases expression | ISO | SDSL (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of SDSL mRNA | CTD | PMID:24449571 | aristolochic acid A | increases expression | ISO | SDSL (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of SDSL mRNA | CTD | PMID:33212167 | atrazine | increases expression | ISO | Sdsl (Rattus norvegicus) | 6480464 | Atrazine results in increased expression of SDSL mRNA | CTD | PMID:36841081 | belinostat | decreases expression | ISO | SDSL (Homo sapiens) | 6480464 | belinostat results in decreased expression of SDSL mRNA | CTD | PMID:26272509 and PMID:27188386 | belinostat | multiple interactions | ISO | SDSL (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SDSL mRNA | CTD | PMID:27188386 | benzo[a]pyrene | decreases expression | ISO | SDSL (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of SDSL mRNA | CTD | PMID:20106945 and PMID:32234424 | benzo[a]pyrene | increases methylation | ISO | SDSL (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of SDSL promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of SDSL mRNA | CTD | PMID:27195522 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of SDSL mRNA | CTD | PMID:22228805 | bisphenol A | affects expression | ISO | Sdsl (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of SDSL mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | Sdsl (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of SDSL mRNA | CTD | PMID:34947998 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SDSL mRNA | CTD | PMID:30245210 | bisphenol A | decreases expression | ISO | Sdsl (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of SDSL mRNA | CTD | PMID:30816183 more ... | bisphenol A | increases expression | ISO | SDSL (Homo sapiens) | 6480464 | bisphenol A results in increased expression of SDSL mRNA | CTD | PMID:29275510 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25620056 | ciguatoxin CTX1B | affects expression | EXP | | 6480464 | Ciguatoxins affects the expression of SDSL mRNA | CTD | PMID:18353800 | clofibrate | decreases expression | EXP | | 6480464 | Clofibrate results in decreased expression of SDSL mRNA | CTD | PMID:17585979 | clofibrate | multiple interactions | EXP | | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of SDSL mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SDSL mRNA] | CTD | PMID:17585979 | copper(II) sulfate | decreases expression | ISO | SDSL (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of SDSL mRNA | CTD | PMID:19549813 | dorsomorphin | multiple interactions | ISO | SDSL (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | endosulfan | increases expression | ISO | Sdsl (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of SDSL mRNA | CTD | PMID:29391264 | ethyl methanesulfonate | increases expression | ISO | SDSL (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of SDSL mRNA | CTD | PMID:23649840 | formaldehyde | increases expression | ISO | SDSL (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of SDSL mRNA | CTD | PMID:23649840 | gallic acid | decreases expression | ISO | SDSL (Homo sapiens) | 6480464 | Gallic Acid results in decreased expression of SDSL mRNA | CTD | PMID:34408198 | hydrogen peroxide | affects expression | ISO | SDSL (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of SDSL mRNA | CTD | PMID:20044591 | indometacin | increases expression | ISO | Sdsl (Rattus norvegicus) | 6480464 | Indomethacin results in increased expression of SDSL mRNA | CTD | PMID:36868495 | inulin | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of SDSL mRNA | CTD | PMID:36331819 | ivermectin | decreases expression | ISO | SDSL (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of SDSL protein | CTD | PMID:32959892 | ketamine | increases expression | ISO | Sdsl (Rattus norvegicus) | 6480464 | Ketamine results in increased expression of SDSL mRNA | CTD | PMID:20080153 | leflunomide | decreases expression | ISO | Sdsl (Rattus norvegicus) | 6480464 | leflunomide results in decreased expression of SDSL mRNA | CTD | PMID:24136188 | lipopolysaccharide | increases expression | EXP | | 6480464 | Lipopolysaccharides results in increased expression of SDSL mRNA | CTD | PMID:27339419 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of SDSL mRNA | CTD | PMID:24535843 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of SDSL mRNA | CTD | PMID:34911549 | paracetamol | multiple interactions | EXP | | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of SDSL mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SDSL mRNA] | CTD | PMID:17585979 | paracetamol | decreases expression | ISO | SDSL (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of SDSL mRNA | CTD | PMID:21420995 and PMID:29067470 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of SDSL mRNA | CTD | PMID:17562736 | pentachlorophenol | increases expression | EXP | | 6480464 | Pentachlorophenol results in increased expression of SDSL mRNA | CTD | PMID:23892564 | perfluorononanoic acid | increases expression | ISO | SDSL (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of SDSL mRNA | CTD | PMID:32588087 | perfluorooctane-1-sulfonic acid | increases expression | ISO | SDSL (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in increased expression of SDSL mRNA | CTD | PMID:32588087 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SDSL mRNA and [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of SDSL mRNA | CTD | PMID:36331819 | phenobarbital | decreases expression | EXP | | 6480464 | Phenobarbital results in decreased expression of SDSL mRNA | CTD | PMID:19482888 | phenobarbital | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of SDSL mRNA and NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of SDSL mRNA] | CTD | PMID:19482888 and PMID:24535843 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of SDSL mRNA | CTD | PMID:18445702 | propiconazole | decreases expression | EXP | | 6480464 | propiconazole results in decreased expression of SDSL mRNA | CTD | PMID:21278054 | resorcinol | decreases expression | ISO | SDSL (Homo sapiens) | 6480464 | resorcinol results in decreased expression of SDSL mRNA | CTD | PMID:22623647 | SB 431542 | multiple interactions | ISO | SDSL (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of SDSL mRNA | CTD | PMID:37682722 | sunitinib | decreases expression | ISO | SDSL (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of SDSL mRNA | CTD | PMID:31533062 | tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of SDSL mRNA | CTD | PMID:17484886 | thapsigargin | increases expression | ISO | SDSL (Homo sapiens) | 6480464 | Thapsigargin results in increased expression of SDSL mRNA | CTD | PMID:29453283 | thioacetamide | decreases expression | ISO | Sdsl (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of SDSL mRNA | CTD | PMID:34492290 | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of SDSL mRNA | CTD | PMID:23557971 | tunicamycin | increases expression | ISO | SDSL (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of SDSL mRNA | CTD | PMID:29453283 | valdecoxib | decreases expression | ISO | Sdsl (Rattus norvegicus) | 6480464 | valdecoxib results in decreased expression of SDSL mRNA | CTD | PMID:24136188 | valproic acid | increases expression | ISO | SDSL (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SDSL mRNA | CTD | PMID:23179753 | valproic acid | affects expression | ISO | SDSL (Homo sapiens) | 6480464 | Valproic Acid affects the expression of SDSL mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | SDSL (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of SDSL mRNA | CTD | PMID:23179753 and PMID:26272509 | valproic acid | multiple interactions | ISO | SDSL (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SDSL mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | Sdsl (Rattus norvegicus) | 6480464 | Valproic Acid results in increased expression of SDSL mRNA | CTD | PMID:29427782 | |