H2ac22 (H2A clustered histone 22)

Gene: H2ac22 (H2A clustered histone 22) Mus musculus

Analyze

Symbol:

H2ac22

Name:

H2A clustered histone 22

RGD ID:

1319218

MGI Page

MGI

Description:

Predicted to enable enzyme binding activity and nucleosomal DNA binding activity. Predicted to be involved in heterochromatin organization. Predicted to be part of CENP-A containing nucleosome. Predicted to be active in nucleus. Orthologous to several human genes including H2AC4 (H2A clustered histone 4) and H2AC8 (H2A clustered histone 8).

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

Hist1; Hist1h2ab; Hist1h2ac; Hist1h2ad; Hist1h2ae; Hist1h2ag; Hist1h2ai; Hist1h2an; Hist1h2ao; histone 1, H2an; histone cluster 1, H2an; histone H2A type 1; Histone H2A type 1-N

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	H2AC11 (H2A clustered histone 11)	HGNC	HomoloGene, OMA, OrthoDB
Rattus norvegicus (Norway rat):	Hist1h2ah (histone cluster 1 H2A family member H)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LOC100982169 (histone H2A type 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	H2AC13 (H2A clustered histone 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	LOC106144641 (histone H2A type 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LOC103221970 (histone H2A type 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	H2AC8 (H2A clustered histone 8)	HGNC	OMA, OrthoMCL, Panther, Treefam
Homo sapiens (human):	H2AC4 (H2A clustered histone 4)	HGNC	OMA, OrthoMCL
Homo sapiens (human):	H2AC15 (H2A clustered histone 15)	HGNC	OMA
Homo sapiens (human):	H2AC16 (H2A clustered histone 16)	HGNC	OMA
Homo sapiens (human):	H2AC25 (H2A clustered histone 25)	HGNC	OMA
Homo sapiens (human):	H2AC17 (H2A clustered histone 17)	HGNC	OMA
Homo sapiens (human):	H2AC7 (H2A clustered histone 7)	HGNC	OMA
Homo sapiens (human):	H2AC14 (H2A clustered histone 14)	HGNC	OMA
Homo sapiens (human):	H2AJ (H2A.J histone)	HGNC	OMA
Homo sapiens (human):	H2AC6 (H2A clustered histone 6)	HGNC	OMA
Homo sapiens (human):	H2AX (H2A.X variant histone)	HGNC	OMA
Homo sapiens (human):	H2AC13 (H2A clustered histone 13)	HGNC	OMA
Homo sapiens (human):	H2AC1 (H2A clustered histone 1)	HGNC	OMA
Homo sapiens (human):	H2AC12 (H2A clustered histone 12)	HGNC	OMA
Homo sapiens (human):	H2AC21 (H2A clustered histone 21)	HGNC	OMA
Homo sapiens (human):	H2AC20 (H2A clustered histone 20)	HGNC	OMA
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Hist1h2an (histone cluster 1, H2an)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	H2AC11 (H2A clustered histone 11)	Alliance	DIOPT (HGNC\|OMA)
Homo sapiens (human):	H2AC4 (H2A clustered histone 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	H2AC8 (H2A clustered histone 8)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Rattus norvegicus (Norway rat):	hist1h2ail2 (histone cluster 1, H2ai-like2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Rattus norvegicus (Norway rat):	Hist1h2af (histone cluster 1 H2A family member F)	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Rattus norvegicus (Norway rat):	H2ac23 (H2A clustered histone 23)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Rattus norvegicus (Norway rat):	H2ac4 (H2A clustered histone 4)	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Rattus norvegicus (Norway rat):	Hist1h2ac (histone cluster 1 H2A family member C)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Rattus norvegicus (Norway rat):	Hist1h2ai (histone cluster 1, H2ai)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Rattus norvegicus (Norway rat):	Hist1h2anl2 (histone cluster 1, H2an like 2)	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)
Danio rerio (zebrafish):	si:ch211-113a14.25	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER)
Danio rerio (zebrafish):	si:ch211-113a14.25	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER)
Danio rerio (zebrafish):	si:dkey-261m9.11	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER)
Danio rerio (zebrafish):	si:ch211-113a14.19	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	HTA1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	His2A:CG31618	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	His2A:CG33808	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	His2A:CG33814	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	His2A:CG33817	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	His2A:CG33820	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	His2A:CG33823	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	His2A:CG33826	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	His2A:CG33829	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	His2A:CG33832	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	His2A:CG33835	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	His2A:CG33838	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	His2A:CG33841	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	His2A:CG33844	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	His2A:CG33847	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	His2A:CG33850	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	His2A:CG33853	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	His2A:CG33856	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	His2A:CG33859	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	His2A:CG33862	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	His2A:CG33865	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	his-12	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	his-16	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	his-19	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	his-21	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	his-3	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	his-30	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	his-33	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	his-35	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	his-43	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	his-47	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	his-51	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	his-53	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	his-57	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	his-61	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	his-65	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	his-68	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	his-7	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	HTA2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	21,970,944 - 21,971,418 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	21,970,996 - 21,971,388 (-)	Ensembl		GRCm39 Ensembl
GRCm38	13	21,786,774 - 21,787,248 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	21,786,826 - 21,787,218 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	21,878,695 - 21,879,087 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	21,794,291 - 21,794,683 (-)	NCBI		MGSCv36	mm8
Celera	13	22,057,691 - 22,058,083 (-)	NCBI		Celera
Cytogenetic Map	13	A3.1	NCBI
cM Map	13	7.97	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

17beta-estradiol (ISO)

2,3',4,4',5-Pentachlorobiphenyl (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-palmitoylglycerol (ISO)

4,4'-diaminodiphenylmethane (EXP)

4,4'-sulfonyldiphenol (EXP)

aflatoxin B1 (ISO)

antimycin A (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (EXP)

berberine (ISO)

bisphenol A (ISO)

cannabidiol (ISO)

carbon nanotube (EXP,ISO)

CGP 52608 (ISO)

coumestrol (ISO)

deguelin (ISO)

dibenz[a,h]anthracene (EXP)

dibenzo[a,l]pyrene (ISO)

dioxygen (ISO)

ethanol (ISO)

fenpyroximate (ISO)

folic acid (ISO)

formaldehyde (ISO)

genistein (ISO)

gentamycin (ISO)

glyphosate (EXP)

graphite (ISO)

indole-3-methanol (ISO)

iron dichloride (ISO)

isotretinoin (ISO)

lidocaine (ISO)

lipopolysaccharide (ISO)

mercury atom (ISO)

mercury(0) (ISO)

methyl methanesulfonate (ISO)

methylparaben (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (EXP)

N-methyl-4-phenylpyridinium (ISO)

N-Nitrosopyrrolidine (ISO)

paracetamol (ISO)

perfluorooctanoic acid (ISO)

picene (ISO)

pyrimidifen (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

sodium arsenite (ISO)

sotorasib (ISO)

tebufenpyrad (ISO)

thifluzamide (ISO)

trametinib (ISO)

trichloroethene (ISO)

valproic acid (ISO)

versicolorin A (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

heterochromatin formation (IBA)

Cellular Component

CENP-A containing nucleosome (ISO)

nucleosome (IBA,ISO)

nucleus (IBA,ISO)

Molecular Function

enzyme binding (ISO)

nucleosomal DNA binding (IBA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

systemic lupus erythematosus pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	MGDs mouse GO annotations	MGD data from the GO Consortium
2.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12408966	PMID:12477932	PMID:21873635	PMID:30550785

Genomics

Comparative Map Data

H2ac22
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	21,970,944 - 21,971,418 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	21,970,996 - 21,971,388 (-)	Ensembl		GRCm39 Ensembl
GRCm38	13	21,786,774 - 21,787,248 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	21,786,826 - 21,787,218 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	21,878,695 - 21,879,087 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	21,794,291 - 21,794,683 (-)	NCBI		MGSCv36	mm8
Celera	13	22,057,691 - 22,058,083 (-)	NCBI		Celera
Cytogenetic Map	13	A3.1	NCBI
cM Map	13	7.97	NCBI

H2AC11
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	27,133,043 - 27,133,535 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	27,133,043 - 27,133,535 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	27,100,822 - 27,101,314 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	27,208,800 - 27,211,050 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	27,208,799 - 27,211,049	NCBI
Celera	6	28,706,816 - 28,709,070 (+)	NCBI		Celera
Cytogenetic Map	6	p22.1	NCBI
HuRef	6	26,908,878 - 26,909,375 (+)	NCBI		HuRef
CHM1_1	6	27,103,139 - 27,103,636 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	27,001,858 - 27,002,350 (+)	NCBI		T2T-CHM13v2.0

Hist1h2ah
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	41,812,378 - 41,812,875 (+)	NCBI		GRCr8
mRatBN7.2	17	41,384,521 - 41,385,018 (+)	NCBI	mRatBN7.2	mRatBN7.2
UTH_Rnor_SHR_Utx	17	41,458,552 - 41,459,049 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	43,062,598 - 43,063,095 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	41,341,255 - 41,341,752 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	43,632,354 - 43,632,851 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	44,747,796 - 44,748,188 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	17	43,632,397 - 43,632,789 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	45,486,769 - 45,487,706 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	48,507,180 - 48,507,572 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	17	41,015,719 - 41,016,216 (+)	NCBI		Celera
Cytogenetic Map	17	p11	NCBI

LOC100982169
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	41,778,697 - 41,781,552 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	37,780,168 - 37,780,711 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	26,966,232 - 26,968,585 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	27,627,997 - 27,630,234 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	27,628,025 - 27,628,417 (+)	Ensembl	panpan1.1		panPan2

H2AC13
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	35	25,000,243 - 25,001,749 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	35	25,000,401 - 25,000,793 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	35	24,856,042 - 24,857,410 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	35	25,189,348 - 25,190,709 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	35	25,189,363 - 25,189,755 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	35	24,964,690 - 24,965,156 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	35	25,017,638 - 25,018,999 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	35	26,481,678 - 26,483,045 (+)	NCBI		UU_Cfam_GSD_1.0

LOC106144641
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	821,802 - 822,543 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936671	2,799,038 - 2,799,430 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936671	2,798,987 - 2,800,593 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LOC103221970
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	45,376,288 - 45,377,527 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	44,694,268 - 44,694,657 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666044	26,827,396 - 26,828,632 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in H2ac22
24 total Variants

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1301890	Adip7_m	adiposity 7 (mouse)			Not determined		13	1	23454672	Mouse
1301227	Skull19_m	skull morphology 19 (mouse)			Not determined		13	1	23454672	Mouse
1301661	Tshp13_m	tooth shape 13 (mouse)			Not determined		13	1	23454672	Mouse
1301255	Cd4ts6_m	CD4 T cell subset 6 (mouse)			Not determined		13	168545	34168684	Mouse
10449140	Eosn2_m	eosinophil differential 2 (mouse)					13	221311	34221311	Mouse
15039338	Nmrs34_m	NAFLD-associated magnetic resonance shift 34 (mouse)					13	221311	34221311	Mouse
1301455	Bmd3_m	bone mineral density 3 (mouse)			Not determined		13	3477612	37477820	Mouse
10045624	Heal24_m	wound healing/regeneration (mouse)			Not determined		13	3477612	37477820	Mouse
10045625	Heal23_m	wound healing/regeneration 23 (mouse)			Not determined		13	3477612	37477820	Mouse
1301367	Twq1_m	testis weight QTL 1 (mouse)			Not determined		13	3615512	37615672	Mouse
1301733	Heal3_m	wound healing/regeneration 3 (mouse)			Not determined		13	3680200	37680343	Mouse
26884393	Humsd7_m	humerus midshaft diameter 7, 16 week (mouse)					13	3950000	76048119	Mouse
1558898	Hpi1_m	hapatic PMN infiltration 1 (mouse)			Not determined		13	4414025	53101640	Mouse
10402494	Igmsc1_m	immunoglobulin M secreting cells 1 (mouse)			Not determined		13	17168545	44918560	Mouse
1301984	Pbd2_m	peak bone density 2 (mouse)			Not determined		13	17189508	38947406	Mouse
1301880	Hypt_m	hypertension (mouse)			Not determined		13	18156792	52156924	Mouse
13463469	Gssq1_m	glomerulosclerosis severity QTL 1 (mouse)					13	19060908	53061050	Mouse
12880423	V25Dq7_m	vitamin D inactive form serum level QTL 7 (mouse)					13	19583983	53583983	Mouse
1301015	Sysbp2_m	systolic blood pressure 2 (mouse)			Not determined		13	20477612	59821605	Mouse
4142147	Mvwf4_m	modifier of von Willebrand factor 4 (mouse)			Not determined			20477612	112898424	Mouse
1357591	Tesq1_m	testis weight QTL 1 (mouse)			Not determined		13	20615512	55720517	Mouse
4142009	Pregq3_m	pregnancy QTL 3 (mouse)			Not determined		13	20615512	72385189	Mouse
10045618	Heal17_m	wound healing/regeneration 17 (mouse)			Not determined		13	20746939	54747056	Mouse

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_178184	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AL589651	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY158912	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466561	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000091751 ⟹ ENSMUSP00000089345

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	13	21,970,996 - 21,971,388 (-)	Ensembl
GRCm38.p6 Ensembl	13	21,786,826 - 21,787,218 (-)	Ensembl

RefSeq Acc Id:

NM_178184 ⟹ NP_835491

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	13	21,970,944 - 21,971,418 (-)	NCBI
GRCm38	13	21,786,774 - 21,787,248 (-)	NCBI
MGSCv37	13	21,878,695 - 21,879,087 (-)	RGD
Celera	13	22,057,637 - 22,058,083 (-)	NCBI
cM Map	13		ENTREZGENE

Sequence:

show sequence

GCAGTTGTCAGTTCTTTCTTTTTGTTTAGAATGTCTGGACGCGGCAAACAGGGCGGCAAGGCTC
GCGCCAAGGCCAAGACCCGCTCCTCCCGGGCCGGCCTGCAGTTCCCCGTGGGCCGCGTGCACCG
GCTGCTCCGCAAGGGCAACTACTCGGAGCGCGTGGGCGCCGGCGCCCCGGTGTACCTGGCGGCC
GTGCTGGAGTACCTGACGGCCGAGATCCTGGAGCTGGCGGGCAACGCGGCCCGCGACAACAAGA
AGACGCGCATCATCCCGCGCCACCTGCAGCTGGCCATCCGCAACGACGAGGAGCTCAACAAGCT
GCTGGGCCGCGTGACCATCGCGCAGGGCGGCGTCCTGCCCAACATCCAGGCCGTACTGCTGCCG
AAGAAGACCGAGAGCCACCACAAGGCCAAGGGAAAATAAGACAATTGTTTCCTGATCATTTAAA
AAACAAAGGCTCTTTTCAGAGCTAACA

hide sequence

Protein Sequences


Protein RefSeqs	NP_835491	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAO06222	(Get FASTA)	NCBI Sequence Viewer
	C0HKE7	(Get FASTA)	NCBI Sequence Viewer
	EDL32628	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000077477.2
	ENSMUSP00000080088.6
	ENSMUSP00000088281.5
	ENSMUSP00000088285.3
	ENSMUSP00000089335.5
	ENSMUSP00000089339.6
	ENSMUSP00000089345
	ENSMUSP00000089345.3
	ENSMUSP00000100034.4
	ENSMUSP00000127684.2

RefSeq Acc Id:	NP_835491 ⟸ NM_178184
- UniProtKB:	Q149U0 (UniProtKB/Swiss-Prot), P22752 (UniProtKB/Swiss-Prot), P10812 (UniProtKB/Swiss-Prot), Q5SZZ2 (UniProtKB/Swiss-Prot), C0HKE9 (UniProtKB/Swiss-Prot), C0HKE8 (UniProtKB/Swiss-Prot), C0HKE7 (UniProtKB/Swiss-Prot), C0HKE6 (UniProtKB/Swiss-Prot), C0HKE5 (UniProtKB/Swiss-Prot), C0HKE4 (UniProtKB/Swiss-Prot), C0HKE3 (UniProtKB/Swiss-Prot), C0HKE2 (UniProtKB/Swiss-Prot), C0HKE1 (UniProtKB/Swiss-Prot), B2RVF0 (UniProtKB/TrEMBL), A0AUV1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEIL ELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAK GK hide sequence

RefSeq Acc Id:

ENSMUSP00000089345 ⟸ ENSMUST00000091751

Protein Domains

Histone H2A C-terminal Histone H2A/H2B/H3

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-C0HKE1-F1-model_v2	AlphaFold	C0HKE1	1-130	view protein structure
AF-C0HKE2-F1-model_v2	AlphaFold	C0HKE2	1-130	view protein structure
AF-C0HKE3-F1-model_v2	AlphaFold	C0HKE3	1-130	view protein structure
AF-C0HKE4-F1-model_v2	AlphaFold	C0HKE4	1-130	view protein structure
AF-C0HKE5-F1-model_v2	AlphaFold	C0HKE5	1-130	view protein structure
AF-C0HKE6-F1-model_v2	AlphaFold	C0HKE6	1-130	view protein structure
AF-C0HKE7-F1-model_v2	AlphaFold	C0HKE7	1-130	view protein structure
AF-C0HKE8-F1-model_v2	AlphaFold	C0HKE8	1-130	view protein structure
AF-C0HKE9-F1-model_v2	AlphaFold	C0HKE9	1-130	view protein structure

Promoters

RGD ID:

8679736

Promoter ID:

EPDNEW_M17898

Type:

multiple initiation site

Name:

Hist1h2an_1

Description:

Mus musculus histone cluster 1, H2an , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	13	21,787,248 - 21,787,308	EPDNEW

RGD ID:

6824033

Promoter ID:

MM_KWN:13403

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

ENSMUST00000091750, NM_178184, OTTMUST00000001016, OTTMUST00000001017

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	13	21,878,016 - 21,880,147 (+)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:2448300	AgrOrtholog
Ensembl Genes	ENSMUSG00000061615	UniProtKB/Swiss-Prot
	ENSMUSG00000069270	UniProtKB/Swiss-Prot
	ENSMUSG00000069272	UniProtKB/Swiss-Prot
	ENSMUSG00000069301	UniProtKB/Swiss-Prot
	ENSMUSG00000069309	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUSG00000071478	UniProtKB/Swiss-Prot
	ENSMUSG00000071516	UniProtKB/Swiss-Prot
	ENSMUSG00000094248	UniProtKB/Swiss-Prot
	ENSMUSG00000094777	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000070124.5	UniProtKB/Swiss-Prot
	ENSMUST00000078369.3	UniProtKB/Swiss-Prot
	ENSMUST00000081342.7	UniProtKB/Swiss-Prot
	ENSMUST00000090776.7	UniProtKB/Swiss-Prot
	ENSMUST00000091741.6	UniProtKB/Swiss-Prot
	ENSMUST00000091745.6	UniProtKB/Swiss-Prot
	ENSMUST00000091751	ENTREZGENE
	ENSMUST00000091751.3	UniProtKB/Swiss-Prot
	ENSMUST00000102969.6	UniProtKB/Swiss-Prot
	ENSMUST00000171127.4	UniProtKB/Swiss-Prot
Gene3D-CATH	1.10.20.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Histone-fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Histone_H2A	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Histone_H2A/H2B/H3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Histone_H2A_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Histone_H2A_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:319164	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	mmu:319165	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	mmu:319166	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	mmu:319167	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	mmu:319170	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	mmu:319171	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	mmu:319172	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	mmu:319191	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	mmu:665433	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD	MGI:2448300	ENTREZGENE
NCBI Gene	319170	ENTREZGENE
PANTHER	HISTONE H2A TYPE 1-D	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR23430	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Histone	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Histone_H2A_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	H2ac22	PhenoGen
PRINTS	HISTONEH2A	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	HISTONE_H2A	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	H2A	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF47113	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0AUV1	ENTREZGENE
	B2RVF0	ENTREZGENE, UniProtKB/TrEMBL
	C0HKE1	ENTREZGENE
	C0HKE2	ENTREZGENE
	C0HKE3	ENTREZGENE
	C0HKE4	ENTREZGENE
	C0HKE5	ENTREZGENE
	C0HKE6	ENTREZGENE
	C0HKE7	ENTREZGENE
	C0HKE8	ENTREZGENE
	C0HKE9	ENTREZGENE
	H2A1B_MOUSE	UniProtKB/Swiss-Prot
	H2A1C_MOUSE	UniProtKB/Swiss-Prot
	H2A1D_MOUSE	UniProtKB/Swiss-Prot
	H2A1E_MOUSE	UniProtKB/Swiss-Prot
	H2A1G_MOUSE	UniProtKB/Swiss-Prot
	H2A1I_MOUSE	UniProtKB/Swiss-Prot
	H2A1N_MOUSE	UniProtKB/Swiss-Prot
	H2A1O_MOUSE	UniProtKB/Swiss-Prot
	H2A1P_MOUSE	UniProtKB/Swiss-Prot
	P10812	ENTREZGENE
	P22752	ENTREZGENE
	Q149U0	ENTREZGENE
	Q5SZZ2	ENTREZGENE
UniProt Secondary	P10812	UniProtKB/Swiss-Prot
	P22752	UniProtKB/Swiss-Prot
	Q149U0	UniProtKB/Swiss-Prot
	Q5SZZ2	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-02-04	H2ac22	H2A clustered histone 22	Hist1h2an	histone cluster 1, H2an	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)