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Gene: Sox6 (SRY (sex determining region Y)-box 6) Mus musculus
Symbol: Sox6
Name: SRY (sex determining region Y)-box 6
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and protein heterodimerization activity. Involved in several processes, including animal organ development; oligodendrocyte cell fate specification; and regulation of gene expression. Localizes to the nucleus. Human ortholog(s) of this gene implicated in malignant glioma. Is expressed in several structures, including 1st branchial arch; alimentary system; genitourinary system; limb; and nervous system. Orthologous to human SOX6 (SRY-box transcription factor 6).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI987981; SOX-LZ; SRY-box containing gene 6; transcription factor SOX-6
Homo sapiens (human) : SOX6 (SRY-box transcription factor 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sox6 (SRY-box transcription factor 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sox6 (SRY-box transcription factor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : SOX6 (SRY-box transcription factor 6)
Canis lupus familiaris (dog) : SOX6 (SRY-box transcription factor 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sox6 (SRY-box transcription factor 6)
Sus scrofa (pig) : SOX6 (SRY-box transcription factor 6)
Chlorocebus sabaeus (African green monkey) : SOX6 (SRY-box transcription factor 6)
Heterocephalus glaber (naked mole-rat) : Sox6 (SRY-box transcription factor 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl7115,470,872 - 116,038,796 (-)Ensembl
GRCm387115,470,872 - 116,040,776 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377122,614,858 - 123,182,258 (-)NCBIGRCm37mm9NCBIm37
MGSCv367115,262,493 - 115,822,196 (-)NCBImm8
Celera7115,421,897 - 115,985,959 (-)NCBICelera
Cytogenetic Map7 F1NCBI
cM Map761.29NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Sox6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319099
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-02-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.