PPP1R3E (protein phosphatase 1 regulatory subunit 3E) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: PPP1R3E (protein phosphatase 1 regulatory subunit 3E) Homo sapiens
Analyze
Symbol: PPP1R3E
Name: protein phosphatase 1 regulatory subunit 3E
RGD ID: 1318988
HGNC Page HGNC:14943
Description: Predicted to enable [phosphorylase] phosphatase activity; glycogen binding activity; and protein phosphatase 1 binding activity. Predicted to be involved in positive regulation of glycogen biosynthetic process. Predicted to be located in glycogen granule. Predicted to be part of protein phosphatase type 1 complex.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: KIAA1443; protein phosphatase 1, regulatory (inhibitor) subunit 3E
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381423,295,652 - 23,302,859 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1423,295,652 - 23,302,859 (-)Ensemblhg38GRCh38
GRCh371423,764,861 - 23,772,068 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361422,832,901 - 22,841,835 (-)NCBIBuild 36Build 36hg18NCBI36
Celera143,627,819 - 3,634,764 (-)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef143,881,804 - 3,888,734 (-)NCBIHuRef
CHM1_11423,763,798 - 23,770,725 (-)NCBICHM1_1
T2T-CHM13v2.01417,496,654 - 17,503,863 (-)NCBIT2T-CHM13v2.0
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. A novel glycogen-targeting subunit of protein phosphatase 1 that is regulated by insulin and shows differential tissue distribution in humans and rodents. Munro S, etal., FEBS J. 2005 Mar;272(6):1478-89.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11948623   PMID:12477932   PMID:14702039   PMID:19773279   PMID:21873635   PMID:22321011   PMID:26760575   PMID:28330616   PMID:29676528   PMID:36931259   PMID:37298108  


Genomics

Comparative Map Data
PPP1R3E
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381423,295,652 - 23,302,859 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1423,295,652 - 23,302,859 (-)Ensemblhg38GRCh38
GRCh371423,764,861 - 23,772,068 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361422,832,901 - 22,841,835 (-)NCBIBuild 36Build 36hg18NCBI36
Celera143,627,819 - 3,634,764 (-)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef143,881,804 - 3,888,734 (-)NCBIHuRef
CHM1_11423,763,798 - 23,770,725 (-)NCBICHM1_1
T2T-CHM13v2.01417,496,654 - 17,503,863 (-)NCBIT2T-CHM13v2.0
Ppp1r3e
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,113,054 - 55,114,995 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1455,110,126 - 55,115,007 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381454,875,597 - 54,877,538 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1454,872,669 - 54,877,550 (-)Ensemblmm10GRCm38
MGSCv371455,494,434 - 55,496,375 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361453,829,802 - 53,833,887 (-)NCBIMGSCv36mm8
Celera1452,681,503 - 52,683,444 (-)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1427.97NCBI
Ppp1r3e
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81532,318,435 - 32,319,595 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.21528,348,443 - 28,349,603 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1528,347,854 - 28,349,603 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1530,194,105 - 30,195,265 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01531,341,307 - 31,342,467 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01529,584,033 - 29,585,193 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01533,535,986 - 33,537,146 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,535,986 - 33,537,146 (-)Ensemblrn6Rnor6.0
Rnor_5.01537,422,932 - 37,424,092 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41532,974,172 - 32,975,332 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1527,926,360 - 27,927,520 (-)NCBICelera
Cytogenetic Map15p13NCBI
Ppp1r3e
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540937,022,140 - 37,023,312 (+)Ensembl
ChiLan1.0NW_00495540937,016,851 - 37,025,125 (+)NCBIChiLan1.0ChiLan1.0
PPP1R3E
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21524,731,153 - 24,734,892 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11423,947,911 - 23,951,382 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0144,118,827 - 4,122,294 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11422,210,106 - 22,217,167 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1422,215,635 - 22,216,794 (-)EnsemblpanPan2panpan1.1
PPP1R3E
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.183,559,296 - 3,564,849 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl83,563,457 - 3,564,524 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha83,507,425 - 3,513,188 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.083,666,878 - 3,672,635 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl83,671,247 - 3,672,314 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,358,489 - 3,364,245 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.083,419,802 - 3,425,549 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.083,681,735 - 3,687,492 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ppp1r3e
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864035,322,381 - 35,325,751 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367221,063,576 - 1,066,617 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367221,062,669 - 1,066,611 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP1R3E
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl775,776,720 - 75,780,649 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1775,770,813 - 75,782,717 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,960,919 - 80,970,099 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP1R3E
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12923,671,906 - 23,675,340 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2923,673,995 - 23,675,136 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605922,743,548 - 22,750,342 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp1r3e
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248209,248,989 - 9,252,604 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248209,246,477 - 9,255,803 (+)NCBIHetGla 1.0HetGla 1.0hetGla2


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 14q11.2(chr14:20151149-23442195)x3 copy number gain See cases [RCV000050914] Chr14:20151149..23442195 [GRCh38]
Chr14:20619308..23911404 [GRCh37]
Chr14:19689148..22981244 [NCBI36]
Chr14:14q11.2		 pathogenic
GRCh38/hg38 14q11.2-12(chr14:20151149-27723796)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051484]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051484]|See cases [RCV000051484] Chr14:20151149..27723796 [GRCh38]
Chr14:20619308..28193002 [GRCh37]
Chr14:19689148..27262842 [NCBI36]
Chr14:14q11.2-12		 pathogenic
GRCh38/hg38 14q11.2-21.2(chr14:20022693-44093672)x3 copy number gain See cases [RCV000143186] Chr14:20022693..44093672 [GRCh38]
Chr14:20490852..44562875 [GRCh37]
Chr14:19560692..43632625 [NCBI36]
Chr14:14q11.2-21.2		 pathogenic
GRCh38/hg38 14q11.2-21.2(chr14:20196945-45284802)x1 copy number loss See cases [RCV000051485] Chr14:20196945..45284802 [GRCh38]
Chr14:20665104..45754005 [GRCh37]
Chr14:19734944..44823755 [NCBI36]
Chr14:14q11.2-21.2		 pathogenic
GRCh38/hg38 14q11.2(chr14:23260803-23763521)x3 copy number gain See cases [RCV000052058] Chr14:23260803..23763521 [GRCh38]
Chr14:23730012..24232730 [GRCh37]
Chr14:22799852..23302570 [NCBI36]
Chr14:14q11.2		 uncertain significance
GRCh38/hg38 14q11.2-21.1(chr14:20000611-38984415)x3 copy number gain See cases [RCV000053803] Chr14:20000611..38984415 [GRCh38]
Chr14:20468770..39453619 [GRCh37]
Chr14:19538610..38523370 [NCBI36]
Chr14:14q11.2-21.1		 pathogenic
GRCh38/hg38 14q11.2-21.1(chr14:20150949-39746154)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053806]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053806]|See cases [RCV000053806] Chr14:20150949..39746154 [GRCh38]
Chr14:20619108..40215358 [GRCh37]
Chr14:19688948..39285109 [NCBI36]
Chr14:14q11.2-21.1		 pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20151149-106855263)x3 copy number gain See cases [RCV000135543] Chr14:20151149..106855263 [GRCh38]
Chr14:20619308..107263478 [GRCh37]
Chr14:19689148..106334523 [NCBI36]
Chr14:14q11.2-32.33		 pathogenic
GRCh38/hg38 14q11.2-12(chr14:20412587-25018120)x3 copy number gain See cases [RCV000137725] Chr14:20412587..25018120 [GRCh38]
Chr14:20880746..25487326 [GRCh37]
Chr14:19950586..24557166 [NCBI36]
Chr14:14q11.2-12		 likely pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20043514-106877229)x3 copy number gain See cases [RCV000143373] Chr14:20043514..106877229 [GRCh38]
Chr14:20511673..107285437 [GRCh37]
Chr14:19581513..106356482 [NCBI36]
Chr14:14q11.2-32.33		 pathogenic
GRCh38/hg38 14q11.2-21.3(chr14:20043513-48642042)x3 copy number gain See cases [RCV000143748] Chr14:20043513..48642042 [GRCh38]
Chr14:20511672..49111245 [GRCh37]
Chr14:19581512..48180995 [NCBI36]
Chr14:14q11.2-21.3		 pathogenic
GRCh37/hg19 14q11.2-22.2(chr14:23164384-54733411)x3 copy number gain See cases [RCV000447658] Chr14:23164384..54733411 [GRCh37]
Chr14:14q11.2-22.2		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19794561-107234280)x3 copy number gain See cases [RCV000446256] Chr14:19794561..107234280 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q11.2-13.1(chr14:19794561-34049214)x3 copy number gain See cases [RCV000448273] Chr14:19794561..34049214 [GRCh37]
Chr14:14q11.2-13.1		 pathogenic
GRCh37/hg19 14q11.2-12(chr14:19100682-28730087) copy number gain not provided [RCV000767822] Chr14:19100682..28730087 [GRCh37]
Chr14:14q11.2-12		 pathogenic
GRCh37/hg19 14q11.2-12(chr14:19794561-27768254)x3 copy number gain See cases [RCV000240285] Chr14:19794561..27768254 [GRCh37]
Chr14:14q11.2-12		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19280733-107287663)x3 copy number gain not provided [RCV000738413] Chr14:19280733..107287663 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19327823-107287663)x3 copy number gain not provided [RCV000738414] Chr14:19327823..107287663 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q11.2(chr14:21717093-24027220)x3 copy number gain not provided [RCV000856644] Chr14:21717093..24027220 [GRCh37]
Chr14:14q11.2		 likely pathogenic
GRCh37/hg19 14q11.2-21.1(chr14:20511672-42881888)x3 copy number gain not provided [RCV001249358] Chr14:20511672..42881888 [GRCh37]
Chr14:14q11.2-21.1		 not provided
GRCh37/hg19 14q11.2-32.33(chr14:20511673-107285437) copy number gain See cases [RCV000512041] Chr14:20511673..107285437 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q11.1-32.33(chr14:19000422-107289053)x3 copy number gain not provided [RCV000738412] Chr14:19000422..107289053 [GRCh37]
Chr14:14q11.1-32.33		 pathogenic
NC_000014.8:g.(?_23242819)_(25103366_?)dup duplication Lysinuric protein intolerance [RCV003105428]|Specific granule deficiency [RCV003105427] Chr14:23242819..25103366 [GRCh37]
Chr14:14q11.2-12		 uncertain significance
NC_000014.8:g.(?_23586696)_(23902941_?)del deletion Specific granule deficiency [RCV003107481] Chr14:23586696..23902941 [GRCh37]
Chr14:14q11.2		 pathogenic
GRCh37/hg19 14q11.2-21.3(chr14:20511672-47481203) copy number gain Seizure [RCV002280625] Chr14:20511672..47481203 [GRCh37]
Chr14:14q11.2-21.3		 pathogenic
GRCh37/hg19 14q11.2-23.1(chr14:20511673-61826023)x3 copy number gain not provided [RCV003485022] Chr14:20511673..61826023 [GRCh37]
Chr14:14q11.2-23.1		 pathogenic
NC_000014.8:g.(21162263_36986276)_(36987308_50713602)del deletion Brain-lung-thyroid syndrome [RCV002221171] Chr14:36986276..36987308 [GRCh37]
Chr14:14q11.2-21.3		 pathogenic
GRCh37/hg19 14q11.2-21.2(chr14:20511672-44829030)x3 copy number gain not provided [RCV001006605] Chr14:20511672..44829030 [GRCh37]
Chr14:14q11.2-21.2		 pathogenic
GRCh37/hg19 14q11.2(chr14:23590841-23823265) copy number gain not specified [RCV002053091] Chr14:23590841..23823265 [GRCh37]
Chr14:14q11.2		 uncertain significance
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:5732
Count of miRNA genes:1078
Interacting mature miRNAs:1324
Transcripts:ENST00000452015, ENST00000558058, ENST00000559314, ENST00000559942, ENST00000560073, ENST00000560913, ENST00000561178, ENST00000561426, ENST00000561437
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH98727  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371423,767,584 - 23,767,717UniSTSGRCh37
Build 361422,837,424 - 22,837,557RGDNCBI36
Celera143,630,291 - 3,630,424RGD
Cytogenetic Map14q11.2UniSTS
HuRef143,884,258 - 3,884,391UniSTS
GeneMap99-GB4 RH Map1419.84UniSTS
RH102162  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371423,765,410 - 23,765,549UniSTSGRCh37
Build 361422,835,250 - 22,835,389RGDNCBI36
Celera143,628,117 - 3,628,256RGD
Cytogenetic Map14q11.2UniSTS
HuRef143,882,084 - 3,882,223UniSTS
GeneMap99-GB4 RH Map1419.84UniSTS
SHGC-30969  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371423,769,160 - 23,769,309UniSTSGRCh37
Build 361422,839,000 - 22,839,149RGDNCBI36
Celera143,631,867 - 3,632,016RGD
Cytogenetic Map14q11.2UniSTS
HuRef143,885,836 - 3,885,985UniSTS
Stanford-G3 RH Map14395.0UniSTS
NCBI RH Map1438.6UniSTS
GeneMap99-G3 RH Map14395.0UniSTS
RH78773  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371423,769,315 - 23,769,450UniSTSGRCh37
Build 361422,839,155 - 22,839,290RGDNCBI36
Celera143,632,022 - 3,632,157RGD
Cytogenetic Map14q11.2UniSTS
HuRef143,885,991 - 3,886,126UniSTS
GeneMap99-GB4 RH Map1420.64UniSTS
NCBI RH Map1431.0UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2253 4973 1726 2351 5 624 1950 465 2269 7304 6470 53 3734 1 852 1744 1617 174 1

Sequence


Ensembl Acc Id: ENST00000452015   ⟹   ENSP00000408288
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1423,295,652 - 23,302,859 (-)Ensembl
Ensembl Acc Id: ENST00000558058   ⟹   ENSP00000453175
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1423,296,035 - 23,301,583 (-)Ensembl
Ensembl Acc Id: ENST00000559314   ⟹   ENSP00000454106
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1423,296,377 - 23,301,539 (-)Ensembl
Ensembl Acc Id: ENST00000559942   ⟹   ENSP00000453437
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1423,298,293 - 23,301,492 (-)Ensembl
Ensembl Acc Id: ENST00000560073
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1423,298,293 - 23,301,243 (-)Ensembl
Ensembl Acc Id: ENST00000560913   ⟹   ENSP00000453543
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1423,298,252 - 23,301,525 (-)Ensembl
Ensembl Acc Id: ENST00000561178
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1423,298,299 - 23,300,940 (-)Ensembl
Ensembl Acc Id: ENST00000561426
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1423,295,915 - 23,296,867 (-)Ensembl
Ensembl Acc Id: ENST00000561437   ⟹   ENSP00000453726
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1423,298,587 - 23,301,475 (-)Ensembl
RefSeq Acc Id: NM_001276318   ⟹   NP_001263247
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381423,295,652 - 23,302,859 (-)NCBI
HuRef143,881,804 - 3,888,734 (-)NCBI
CHM1_11423,763,798 - 23,770,725 (-)NCBI
T2T-CHM13v2.01417,496,654 - 17,503,863 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001263247   ⟸   NM_001276318
- UniProtKB: D3DS47 (UniProtKB/Swiss-Prot),   Q9H7J1 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSP00000453175   ⟸   ENST00000558058
Ensembl Acc Id: ENSP00000454106   ⟸   ENST00000559314
Ensembl Acc Id: ENSP00000453437   ⟸   ENST00000559942
Ensembl Acc Id: ENSP00000408288   ⟸   ENST00000452015
Ensembl Acc Id: ENSP00000453543   ⟸   ENST00000560913
Ensembl Acc Id: ENSP00000453726   ⟸   ENST00000561437
Protein Domains
CBM21

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9H7J1-F1-model_v2 AlphaFold Q9H7J1 1-279 view protein structure

Promoters
RGD ID:6791807
Promoter ID:HG_KWN:19011
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NR_026862
Position:
Human AssemblyChrPosition (strand)Source
Build 361422,841,346 - 22,841,877 (-)MPROMDB
RGD ID:7227121
Promoter ID:EPDNEW_H19306
Type:initiation region
Name:PPP1R3E_1
Description:protein phosphatase 1 regulatory subunit 3E
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H19307  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381423,301,531 - 23,301,591EPDNEW
RGD ID:7227123
Promoter ID:EPDNEW_H19307
Type:initiation region
Name:PPP1R3E_2
Description:protein phosphatase 1 regulatory subunit 3E
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H19306  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381423,302,851 - 23,302,911EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:14943 AgrOrtholog
COSMIC PPP1R3E COSMIC
Ensembl Genes ENSG00000235194 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000452015 ENTREZGENE
  ENST00000452015.9 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.2440 UniProtKB/Swiss-Prot
GTEx ENSG00000235194 GTEx
HGNC ID HGNC:14943 ENTREZGENE
Human Proteome Map PPP1R3E Human Proteome Map
InterPro CBM21_dom UniProtKB/Swiss-Prot
  CBM21_dom_sf UniProtKB/Swiss-Prot
  PP1_regulatory_subunit_3 UniProtKB/Swiss-Prot
KEGG Report hsa:90673 UniProtKB/Swiss-Prot
NCBI Gene 90673 ENTREZGENE
OMIM 619540 OMIM
PANTHER PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT UniProtKB/Swiss-Prot
  PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3E UniProtKB/Swiss-Prot
Pfam CBM_21 UniProtKB/Swiss-Prot
PharmGKB PA33655 PharmGKB
PROSITE CBM21 UniProtKB/Swiss-Prot
UniProt D3DS47 ENTREZGENE
  H0YLE3_HUMAN UniProtKB/TrEMBL
  H0YM26_HUMAN UniProtKB/TrEMBL
  H0YMB9_HUMAN UniProtKB/TrEMBL
  H0YMS8_HUMAN UniProtKB/TrEMBL
  H0YNQ2_HUMAN UniProtKB/TrEMBL
  PPR3E_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary D3DS47 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-24 PPP1R3E  protein phosphatase 1 regulatory subunit 3E    protein phosphatase 1, regulatory subunit 3E  Symbol and/or name change 5135510 APPROVED
2011-10-11 PPP1R3E  protein phosphatase 1, regulatory subunit 3E  PPP1R3E  protein phosphatase 1, regulatory (inhibitor) subunit 3E  Symbol and/or name change 5135510 APPROVED