Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Trmt6 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TRMT6 mRNA] | CTD | PMID:31150632 | 1,2-dichloroethane | increases expression | EXP | | 6480464 | ethylene dichloride results in increased expression of TRMT6 mRNA | CTD | PMID:28960355 | 1-chloro-2,4-dinitrobenzene | affects binding | ISO | TRMT6 (Homo sapiens) | 6480464 | Dinitrochlorobenzene binds to TRMT6 protein | CTD | PMID:32991956 | 17beta-estradiol | decreases expression | ISO | Trmt6 (Rattus norvegicus) | 6480464 | Estradiol results in decreased expression of TRMT6 mRNA | CTD | PMID:32145629 | 17beta-estradiol | increases expression | ISO | TRMT6 (Homo sapiens) | 6480464 | Estradiol results in increased expression of TRMT6 mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with AHR gene mutant form] results in decreased expression of TRMT6 mRNA | CTD | PMID:19465110 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Trmt6 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TRMT6 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of TRMT6 mRNA | CTD | PMID:21570461 | 2-hydroxypropanoic acid | decreases expression | ISO | TRMT6 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of TRMT6 mRNA | CTD | PMID:30851411 | 3-chloropropane-1,2-diol | increases expression | ISO | Trmt6 (Rattus norvegicus) | 6480464 | alpha-Chlorohydrin results in increased expression of TRMT6 protein | CTD | PMID:34915118 | acrolein | multiple interactions | ISO | TRMT6 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TRMT6 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TRMT6 mRNA | CTD | PMID:32699268 | acrylamide | increases expression | ISO | Trmt6 (Rattus norvegicus) | 6480464 | Acrylamide results in increased expression of TRMT6 mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases expression | ISO | TRMT6 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of TRMT6 mRNA | CTD | PMID:22100608 | alpha-pinene | multiple interactions | ISO | TRMT6 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TRMT6 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TRMT6 mRNA | CTD | PMID:32699268 | antirheumatic drug | decreases expression | ISO | TRMT6 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of TRMT6 mRNA | CTD | PMID:24449571 | benzo[a]pyrene | increases mutagenesis | ISO | TRMT6 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased mutagenesis of TRMT6 gene | CTD | PMID:25435355 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of TRMT6 mRNA | CTD | PMID:22228805 | benzo[a]pyrene diol epoxide I | increases expression | ISO | TRMT6 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:26238291 | bisphenol A | increases expression | ISO | Trmt6 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of TRMT6 mRNA | CTD | PMID:25181051 and PMID:30816183 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TRMT6 mRNA | CTD | PMID:33221593 | bisphenol A | affects expression | ISO | Trmt6 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of TRMT6 mRNA | CTD | PMID:32145629 | bisphenol A | decreases expression | ISO | TRMT6 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of TRMT6 mRNA | CTD | PMID:29275510 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | chromium(6+) | affects expression | EXP | | 6480464 | chromium hexavalent ion affects the expression of TRMT6 mRNA | CTD | PMID:28472532 | cocaine | decreases expression | ISO | Trmt6 (Rattus norvegicus) | 6480464 | Cocaine results in decreased expression of TRMT6 mRNA | CTD | PMID:17898221 | copper(II) sulfate | increases expression | ISO | TRMT6 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of TRMT6 mRNA | CTD | PMID:19549813 | coumestrol | multiple interactions | ISO | TRMT6 (Homo sapiens) | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of TRMT6 mRNA | CTD | PMID:19167446 | cyclosporin A | increases expression | ISO | TRMT6 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of TRMT6 mRNA | CTD | PMID:20106945 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of TRMT6 mRNA | CTD | PMID:21266533 | dioxygen | multiple interactions | EXP | | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of TRMT6 mRNA | CTD | PMID:30529165 | diuron | increases expression | ISO | Trmt6 (Rattus norvegicus) | 6480464 | Diuron results in increased expression of TRMT6 mRNA | CTD | PMID:21551480 | flutamide | increases expression | ISO | Trmt6 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of TRMT6 mRNA | CTD | PMID:24136188 | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of TRMT6 mRNA | CTD | PMID:25629700 | furan | increases expression | ISO | Trmt6 (Rattus norvegicus) | 6480464 | furan results in increased expression of TRMT6 mRNA | CTD | PMID:25539665 | gentamycin | decreases expression | ISO | Trmt6 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of TRMT6 mRNA | CTD | PMID:33387578 | hydrogen peroxide | affects expression | ISO | TRMT6 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of TRMT6 mRNA | CTD | PMID:20044591 | indole-3-methanol | affects expression | ISO | Trmt6 (Rattus norvegicus) | 6480464 | indole-3-carbinol affects the expression of TRMT6 mRNA | CTD | PMID:21396975 | methylmercury chloride | increases expression | ISO | TRMT6 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of TRMT6 mRNA | CTD | PMID:28001369 | nickel atom | increases expression | ISO | TRMT6 (Homo sapiens) | 6480464 | Nickel results in increased expression of TRMT6 mRNA | CTD | PMID:25583101 | nickel sulfate | decreases expression | ISO | TRMT6 (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of TRMT6 mRNA | CTD | PMID:22714537 | ozone | multiple interactions | ISO | TRMT6 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TRMT6 mRNA more ... | CTD | PMID:32699268 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of TRMT6 mRNA | CTD | PMID:34911549 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of TRMT6 mRNA | CTD | PMID:17562736 | paraquat | increases expression | ISO | Trmt6 (Rattus norvegicus) | 6480464 | Paraquat results in increased expression of TRMT6 mRNA | CTD | PMID:32680482 | pentachlorophenol | increases expression | EXP | | 6480464 | Pentachlorophenol results in increased expression of TRMT6 mRNA | CTD | PMID:23892564 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of TRMT6 mRNA | CTD | PMID:36331819 | perfluorooctanoic acid | increases expression | ISO | Trmt6 (Rattus norvegicus) | 6480464 | perfluorooctanoic acid results in increased expression of TRMT6 mRNA | CTD | PMID:19162173 | rac-lactic acid | decreases expression | ISO | TRMT6 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of TRMT6 mRNA | CTD | PMID:30851411 | resveratrol | multiple interactions | ISO | TRMT6 (Homo sapiens) | 6480464 | [Coumestrol co-treated with Resveratrol] results in increased expression of TRMT6 mRNA and [Plant Extracts co-treated with Resveratrol] results in increased expression of TRMT6 mRNA | CTD | PMID:19167446 and PMID:23557933 | sodium arsenate | increases expression | EXP | | 6480464 | sodium arsenate results in increased expression of TRMT6 mRNA | CTD | PMID:21795629 | sodium arsenite | decreases expression | ISO | TRMT6 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of TRMT6 mRNA | CTD | PMID:22714537 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of TRMT6 mRNA | CTD | PMID:37682722 | sodium dichromate | increases expression | ISO | Trmt6 (Rattus norvegicus) | 6480464 | sodium bichromate results in increased expression of TRMT6 mRNA | CTD | PMID:25993096 | succimer | multiple interactions | EXP | | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of TRMT6 mRNA | CTD | PMID:21641980 | sunitinib | increases expression | ISO | TRMT6 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of TRMT6 mRNA | CTD | PMID:31533062 | tetrachloromethane | multiple interactions | ISO | Trmt6 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TRMT6 mRNA] | CTD | PMID:31150632 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of TRMT6 mRNA | CTD | PMID:31919559 | tetrachloromethane | increases expression | ISO | Trmt6 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in increased expression of TRMT6 mRNA | CTD | PMID:31150632 | thioacetamide | increases expression | ISO | Trmt6 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of TRMT6 mRNA | CTD | PMID:23411599 and PMID:34492290 | toluene | decreases expression | ISO | Trmt6 (Rattus norvegicus) | 6480464 | Toluene results in decreased expression of TRMT6 mRNA | CTD | PMID:22967744 | urethane | decreases expression | ISO | TRMT6 (Homo sapiens) | 6480464 | Urethane results in decreased expression of TRMT6 mRNA | CTD | PMID:28818685 | valproic acid | decreases methylation | ISO | TRMT6 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of TRMT6 gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | TRMT6 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TRMT6 mRNA | CTD | PMID:23179753 | vinclozolin | increases expression | ISO | Trmt6 (Rattus norvegicus) | 6480464 | vinclozolin results in increased expression of TRMT6 mRNA | CTD | PMID:20566332 | |