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Gene: Brf2 (BRF2, RNA polymerase III transcription initiation factor 50kDa subunit) Mus musculus
Symbol: Brf2
Name: BRF2, RNA polymerase III transcription initiation factor 50kDa subunit
Description: Predicted to have RNA polymerase III type 3 promoter sequence-specific DNA binding activity and transcription factor binding activity. Predicted to be involved in RNA polymerase III preinitiation complex assembly; cellular response to oxidative stress; and regulation of transcription by RNA polymerase III. Predicted to localize to the transcription factor TFIIIB complex. Orthologous to human BRF2 (BRF2 RNA polymerase III transcription initiation factor subunit); PARTICIPATES IN RNA polymerase III transcription pathway; INTERACTS WITH paracetamol; 17beta-estradiol (ortholog); 2,4-dinitrotoluene (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2700059M06Rik; 5730512K07Rik; AU018504; AU022602; B-related factor 2; BRF-2; BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like; BRFU; TFIIIB50; transcription factor IIIB 50 kDa subunit
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38827,123,339 - 27,128,715 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37828,234,304 - 28,239,104 (-)NCBIGRCm37mm9NCBIm37
MGSCv36828,589,768 - 28,594,568 (-)NCBImm8
Celera828,613,490 - 28,618,293 (-)NCBICelera
Cytogenetic Map8 A2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Brf2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318807
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.