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Gene: SMC1B (structural maintenance of chromosomes 1B) Homo sapiens
Symbol: SMC1B
Name: structural maintenance of chromosomes 1B
Description: Predicted to have ATP binding activity and DNA binding activity. Predicted to be involved in meiotic cell cycle and sister chromatid cohesion. Localizes to cytosol; meiotic cohesin complex; and nucleoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bK268H5; bK268H5.5; FLJ43748; mitosis-specific chromosome segregation protein like protein beta; SMC protein 1B; SMC-1-beta; SMC-1B; SMC1 (structural maintenance of chromosomes 1, yeast)-like 1; SMC1 structural maintenance of chromosomes 1-like 2; SMC1BETA; SMC1L2; structural maintenance of chromosomes protein 1B
Mus musculus (house mouse) : Smc1b (structural maintenance of chromosomes 1B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Smc1b (structural maintenance of chromosomes 1B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smc1b (structural maintenance of chromosomes 1B)
Pan paniscus (bonobo/pygmy chimpanzee) : SMC1B (structural maintenance of chromosomes 1B)
Canis lupus familiaris (dog) : SMC1B (structural maintenance of chromosomes 1B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smc1b (structural maintenance of chromosomes 1B)
Sus scrofa (pig) : SMC1B (structural maintenance of chromosomes 1B)
Chlorocebus sabaeus (African green monkey) : SMC1B (structural maintenance of chromosomes 1B)
Heterocephalus glaber (naked mole-rat) : Smc1b (structural maintenance of chromosomes 1B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2245,344,063 - 45,413,619 (-)EnsemblGRCh38hg38GRCh38
GRCh382245,344,063 - 45,413,671 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372245,739,944 - 45,809,500 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362244,118,608 - 44,188,164 (-)NCBINCBI36hg18NCBI36
Build 342244,060,894 - 44,130,037NCBI
Celera2229,651,346 - 29,720,883 (-)NCBI
Cytogenetic Map22q13.31NCBI
HuRef2228,686,036 - 28,755,615 (-)NCBIHuRef
CHM1_12245,698,500 - 45,768,222 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SMC1B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318766
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-07-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.