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Gene: SOX12 (SRY-box transcription factor 12) Homo sapiens
Symbol: SOX12
Name: SRY-box transcription factor 12
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; transcription coactivator activity; and transcription regulatory region sequence-specific DNA binding activity. Involved in cell fate commitment. Localizes to nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: SOX-22 protein; SOX22; SRY (sex determining region Y)-box 12; SRY (sex determining region Y)-box 22; SRY box 12; SRY-box 12; SRY-related HMG-box gene 22; transcription factor SOX-12
Mus musculus (house mouse) : Sox12 (SRY (sex determining region Y)-box 12)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sox12 (SRY-box transcription factor 12)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sox12 (SRY-box transcription factor 12)
Pan paniscus (bonobo/pygmy chimpanzee) : SOX12 (SRY-box transcription factor 12)
Canis lupus familiaris (dog) : SOX12 (SRY-box transcription factor 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sox12 (SRY-box transcription factor 12)
Sus scrofa (pig) : SOX12 (SRY-box transcription factor 12)
Chlorocebus sabaeus (African green monkey) : SOX12 (SRY-box transcription factor 12)
Heterocephalus glaber (naked mole-rat) : Sox12 (SRY-box transcription factor 12)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl20325,595 - 330,224 (+)EnsemblGRCh38hg38GRCh38
GRCh3820325,571 - 330,228 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3720306,215 - 310,872 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3620254,239 - 258,868 (+)NCBINCBI36hg18NCBI36
Build 3420254,238 - 258,865NCBI
Celera20401,079 - 405,712 (+)NCBI
Cytogenetic Map20p13NCBI
HuRef20257,640 - 262,301 (+)NCBIHuRef
CHM1_120306,210 - 310,867 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SOX12
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318728
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.