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Gene: Spred1 (sprouty protein with EVH-1 domain 1, related sequence) Mus musculus
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Symbol: Spred1
Name: sprouty protein with EVH-1 domain 1, related sequence
Description: Exhibits protein kinase binding activity; protein serine/threonine kinase inhibitor activity; and stem cell factor receptor binding activity. Involved in negative regulation of cell migration involved in sprouting angiogenesis; positive regulation of DNA damage response, signal transduction by p53 class mediator; and regulation of protein modification process. Predicted to colocalize with the cytoplasmic vesicle. Is expressed in several structures, including foregut-midgut junction; metanephros; and telencephalon. Orthologous to human SPRED1 (sprouty related EVH1 domain containing 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 5730461F13Rik; AL024345; AW047647; sprouty-related protein 1 with EVH-1 domain; sprouty-related, EVH1 domain-containing protein 1
Orthologs:
Homo sapiens (human) : SPRED1 (sprouty related EVH1 domain containing 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Spred1 (sprouty-related, EVH1 domain containing 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spred1 (sprouty related EVH1 domain containing 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SPRED1 (sprouty related EVH1 domain containing 1)
Canis lupus familiaris (dog) : SPRED1 (sprouty related EVH1 domain containing 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spred1 (sprouty related EVH1 domain containing 1)
Sus scrofa (pig) : SPRED1 (sprouty related EVH1 domain containing 1)
Chlorocebus sabaeus (African green monkey) : SPRED1 (sprouty related EVH1 domain containing 1)
Heterocephalus glaber (naked mole-rat) : Spred1 (sprouty related EVH1 domain containing 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl2117,121,374 - 117,182,279 (+)Ensembl
GRCm382117,121,071 - 117,182,279 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372116,947,186 - 117,005,073 (+)NCBIGRCm37mm9NCBIm37
MGSCv362116,812,891 - 116,870,778 (+)NCBImm8
Celera2118,249,114 - 118,309,905 (+)NCBICelera
Cytogenetic Map2 E5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Spred1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318684
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.