Mnt (max binding protein) - Rat Genome Database
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Gene: Mnt (max binding protein) Mus musculus
Analyze
Symbol: Mnt
Name: max binding protein
RGD ID: 1318598
MGI Page MGI
Description: Is expressed in several structures, including central nervous system; early conceptus; future brain; genitourinary system; and retina nuclear layer. Used to study Miller-Dieker lissencephaly syndrome. Orthologous to human MNT (MAX network transcriptional repressor); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; bis(2-chloroethyl) sulfide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bHLHd; bHLHd3; max-binding protein MNT; myc antagonist MNT; R; Rox
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391174,721,651 - 74,736,551 (+)NCBIGRCm39mm39
GRCm39 Ensembl1174,721,746 - 74,736,551 (+)Ensembl
GRCm381174,830,806 - 74,845,725 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1174,830,920 - 74,845,725 (+)EnsemblGRCm38mm10GRCm38
MGSCv371174,644,426 - 74,659,227 (+)NCBIGRCm37mm9NCBIm37
MGSCv361174,647,119 - 74,661,905 (+)NCBImm8
Celera1182,343,824 - 82,358,621 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.76NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Additional References at PubMed
PMID:8889548   PMID:9000049   PMID:9184233   PMID:9199935   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:12905154   PMID:12970171   PMID:14610273  
PMID:14681479   PMID:14712062   PMID:14749372   PMID:15028671   PMID:15226823   PMID:15741177   PMID:15782199   PMID:15866886   PMID:16103876   PMID:16141072   PMID:16141073   PMID:16507988  
PMID:16740691   PMID:18287559   PMID:18557763   PMID:18799693   PMID:19086036   PMID:20059953   PMID:20412781   PMID:21350014   PMID:21400495   PMID:21677750   PMID:21873635   PMID:23150551  
PMID:24952961   PMID:28800127   PMID:31978211  


Genomics

Comparative Map Data
Mnt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391174,721,651 - 74,736,551 (+)NCBIGRCm39mm39
GRCm39 Ensembl1174,721,746 - 74,736,551 (+)Ensembl
GRCm381174,830,806 - 74,845,725 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1174,830,920 - 74,845,725 (+)EnsemblGRCm38mm10GRCm38
MGSCv371174,644,426 - 74,659,227 (+)NCBIGRCm37mm9NCBIm37
MGSCv361174,647,119 - 74,661,905 (+)NCBImm8
Celera1182,343,824 - 82,358,621 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.76NCBI
MNT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl172,384,073 - 2,401,104 (-)EnsemblGRCh38hg38GRCh38
GRCh38172,384,073 - 2,401,060 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37172,287,367 - 2,304,354 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36172,234,104 - 2,251,008 (-)NCBINCBI36hg18NCBI36
Build 34172,234,104 - 2,251,008NCBI
Celera172,303,467 - 2,320,377 (-)NCBI
Cytogenetic Map17p13.3NCBI
HuRef172,180,902 - 2,197,281 (-)NCBIHuRef
CHM1_1172,294,735 - 2,311,639 (-)NCBICHM1_1
Mnt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21059,699,208 - 59,714,848 (+)NCBI
Rnor_6.0 Ensembl1061,685,241 - 61,700,491 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01061,683,776 - 61,700,504 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01061,406,915 - 61,422,240 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41062,146,582 - 62,161,832 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11062,160,228 - 62,175,455 (+)NCBI
Celera1058,730,122 - 58,745,364 (+)NCBICelera
Cytogenetic Map10q24NCBI
Mnt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955481852,879 - 866,643 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955481852,539 - 866,731 (+)NCBIChiLan1.0ChiLan1.0
MNT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1172,259,659 - 2,275,285 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0172,375,414 - 2,392,423 (-)NCBIMhudiblu_PPA_v0panPan3
MNT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl946,469,426 - 46,482,705 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1946,466,879 - 46,482,467 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Mnt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365388,439,548 - 8,456,021 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MNT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1248,469,234 - 48,486,729 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11248,469,230 - 48,486,737 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MNT
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1162,015,450 - 2,032,742 (-)NCBI
ChlSab1.1 Ensembl162,014,450 - 2,033,024 (-)Ensembl
Mnt
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247865,039,699 - 5,057,789 (-)NCBI

Position Markers
UniSTS:236639  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381174,844,628 - 74,844,879UniSTSGRCm38
MGSCv371174,658,130 - 74,658,381UniSTSGRCm37
Celera1182,357,524 - 82,357,775UniSTS
Cytogenetic Map11B-CUniSTS
PMC148819P8  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381174,836,387 - 74,836,596UniSTSGRCm38
MGSCv371174,649,889 - 74,650,098UniSTSGRCm37
Celera1182,349,283 - 82,349,492UniSTS
Cytogenetic Map11B-CUniSTS
PMC310661P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381174,836,798 - 74,836,914UniSTSGRCm38
MGSCv371174,650,300 - 74,650,416UniSTSGRCm37
Celera1182,349,694 - 82,349,810UniSTS
Cytogenetic Map11B-CUniSTS
G54861  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381174,837,415 - 74,837,658UniSTSGRCm38
MGSCv371174,650,917 - 74,651,160UniSTSGRCm37
Celera1182,350,311 - 82,350,554UniSTS
Cytogenetic Map11B-CUniSTS
Mnt  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11B-CUniSTS
cM Map1145.76UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114236579176365904Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114236579176365904Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114473921176963931Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115859972974863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116179599488808902Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116226517996265327Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116342858181939647Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116342858194173092Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166842594100842826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166842594100842826Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66842594100842826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166842594100842826Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166842594100842826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166842594100842826Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116718736579923086Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168300000102000000Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170800372104800540Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170800372104800540Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170800372104800540Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170800372104800540Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172128823106128908Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117231897084840636Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172835299106835463Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172927789106927907Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172927789106927907Mouse
12903994Opfaq3_mopen field activity QTL 3 (mouse)117384671582178599Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir210mmu-miR-210-3pOncomiRDBexternal_infoNANA19652553

Predicted Target Of
Summary Value
Count of predictions:1760
Count of miRNA genes:723
Interacting mature miRNAs:947
Transcripts:ENSMUST00000000291, ENSMUST00000132150, ENSMUST00000133217
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000000291   ⟹   ENSMUSP00000000291
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1174,830,920 - 74,845,725 (+)Ensembl
RefSeq Acc Id: ENSMUST00000132150   ⟹   ENSMUSP00000118435
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1174,837,468 - 74,843,775 (+)Ensembl
RefSeq Acc Id: ENSMUST00000133217
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1174,836,326 - 74,837,723 (+)Ensembl
RefSeq Acc Id: NM_010813   ⟹   NP_034943
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,721,750 - 74,736,551 (+)NCBI
GRCm381174,830,924 - 74,845,725 (+)NCBI
MGSCv371174,644,426 - 74,659,227 (+)RGD
Celera1182,343,824 - 82,358,621 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006532402   ⟹   XP_006532465
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,721,651 - 74,736,551 (+)NCBI
GRCm381174,830,806 - 74,845,725 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006532403   ⟹   XP_006532466
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,729,236 - 74,736,551 (+)NCBI
GRCm381174,838,407 - 74,845,725 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036156377   ⟹   XP_036012270
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391174,731,008 - 74,736,551 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_034943   ⟸   NM_010813
- UniProtKB: O08789 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006532465   ⟸   XM_006532402
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006532466   ⟸   XM_006532403
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000000291   ⟸   ENSMUST00000000291
RefSeq Acc Id: ENSMUSP00000118435   ⟸   ENSMUST00000132150
RefSeq Acc Id: XP_036012270   ⟸   XM_036156377
- Peptide Label: isoform X2
Protein Domains
bHLH

Promoters
RGD ID:6821326
Promoter ID:MM_KWN:8459
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000013930,   UC007KCJ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361174,643,431 - 74,644,202 (+)MPROMDB
RGD ID:6821329
Promoter ID:MM_KWN:8460
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:OTTMUST00000013932
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361174,649,731 - 74,650,231 (+)MPROMDB
RGD ID:6821327
Promoter ID:MM_KWN:8461
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   Liver,   MEF_B6,   Spleen
Transcripts:OTTMUST00000013931
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361174,651,121 - 74,651,621 (+)MPROMDB
RGD ID:8675508
Promoter ID:EPDNEW_M15785
Type:initiation region
Name:Mnt_1
Description:Mus musculus max binding protein , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381174,830,984 - 74,831,044EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109150 AgrOrtholog
Ensembl Genes ENSMUSG00000000282 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000000291 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000118435 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000000291 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000132150 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:17428 UniProtKB/Swiss-Prot
MGD MGI:109150 ENTREZGENE
NCBI Gene 17428 ENTREZGENE
Pfam HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mnt PhenoGen
PROSITE BHLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt MNT_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3UGG9_MOUSE UniProtKB/TrEMBL
  Q5SWE2_MOUSE UniProtKB/TrEMBL
UniProt Secondary P97349 UniProtKB/Swiss-Prot
  Q6GTJ3 UniProtKB/Swiss-Prot