Gene: TMC1 (transmembrane channel like 1) Homo sapiens
Symbol: TMC1
Name: transmembrane channel like 1
Description: This gene is considered a member of a gene family predicted to encode transmembrane proteins. The specific function of this gene is unknown; however, it is known to be required for normal function of cochlear hair cells. Mutations in this gene have been associated with progressive postlingual hearing loss and profound prelingual deafness. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DFNA36; DFNB11; DFNB7; transmembrane channel-like 1; transmembrane channel-like protein 1; transmembrane cochlear-expressed protein 1; transmembrane, cochlear expressed, 1
Mus musculus (house mouse) : Tmc1 (transmembrane channel-like gene family 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tmc1 (transmembrane channel-like 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmc1 (transmembrane channel like 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TMC1 (transmembrane channel like 1)
Canis lupus familiaris (dog) : TMC1 (transmembrane channel like 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmc1 (transmembrane channel like 1)
Sus scrofa (pig) : TMC1 (transmembrane channel like 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38972,521,801 - 72,836,351 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37975,136,717 - 75,451,267 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36974,326,537 - 74,641,087 (+)NCBINCBI36hg18NCBI36
Build 34972,366,270 - 72,680,821NCBI
Celera945,709,595 - 46,024,123 (+)NCBI
Cytogenetic Map9q21.13NCBI
HuRef944,959,937 - 45,274,606 (+)NCBIHuRef
CHM1_1975,283,347 - 75,597,903 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TMC1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318596
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-05-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.