Gene: TMC1 (transmembrane channel like 1) Homo sapiens
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Symbol: TMC1
Name: transmembrane channel like 1
Description: This gene is considered a member of a gene family predicted to encode transmembrane proteins. The specific function of this gene is unknown; however, it is known to be required for normal function of cochlear hair cells. Mutations in this gene have been associated with progressive postlingual hearing loss and profound prelingual deafness. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DFNA36; DFNB11; DFNB7; transmembrane channel-like 1; transmembrane channel-like protein 1; transmembrane cochlear-expressed protein 1; transmembrane, cochlear expressed, 1
Orthologs:
Mus musculus (house mouse) : Tmc1 (transmembrane channel-like gene family 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tmc1 (transmembrane channel-like 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmc1 (transmembrane channel like 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TMC1 (transmembrane channel like 1)
Canis lupus familiaris (dog) : TMC1 (transmembrane channel like 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmc1 (transmembrane channel like 1)
Sus scrofa (pig) : TMC1 (transmembrane channel like 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38972,521,801 - 72,836,351 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37975,136,717 - 75,451,267 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36974,326,537 - 74,641,087 (+)NCBINCBI36hg18NCBI36
Build 34972,366,270 - 72,680,821NCBI
Celera945,709,595 - 46,024,123 (+)NCBI
Cytogenetic Map9q21.13NCBI
HuRef944,959,937 - 45,274,606 (+)NCBIHuRef
CHM1_1975,283,347 - 75,597,903 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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References - curated
References - uncurated
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Sequence

Nucleotide Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on TMC1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318596
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-05-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.