Mtrr (5-methyltetrahydrofolate-homocysteine methyltransferase reductase) - Rat Genome Database

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Gene: Mtrr (5-methyltetrahydrofolate-homocysteine methyltransferase reductase) Mus musculus
Analyze
Symbol: Mtrr
Name: 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
RGD ID: 1318581
MGI Page MGI
Description: Enables [methionine synthase] reductase activity. Involved in several processes, including S-adenosylmethionine cycle; carboxylic acid metabolic process; and cobalamin metabolic process. Predicted to be located in intermediate filament cytoskeleton and nucleoplasm. Predicted to be active in cytosol. Is expressed in several structures, including gut; neural ectoderm; notochord; optic vesicle; and placenta. Human ortholog(s) of this gene implicated in several diseases, including endocrine gland cancer (multiple); heart disease (multiple); hematologic cancer (multiple); homocystinuria; and homocystinuria-megaloblastic anemia cblE type. Orthologous to human MTRR (5-methyltetrahydrofolate-homocysteine methyltransferase reductase).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 4732420G08; aqCbl reductase; aquacobalamin reductase; methionine synthase reductase; MSR
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391368,708,899 - 68,730,288 (-)NCBIGRCm39mm39
GRCm39 Ensembl1368,708,899 - 68,730,268 (-)Ensembl
GRCm381368,560,780 - 68,582,169 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1368,560,780 - 68,582,149 (-)EnsemblGRCm38mm10GRCm38
MGSCv371368,699,657 - 68,720,998 (-)NCBIGRCm37mm9NCBIm37
MGSCv361369,028,151 - 69,049,492 (-)NCBImm8
Celera1370,920,592 - 70,941,889 (-)NCBICelera
Cytogenetic Map13B3NCBI
cM Map1335.54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
1. Aneiros-Guerrero A, etal., BMC Med Genet. 2011 May 26;12:75.
2. Bethke L, etal., Cancer Epidemiol Biomarkers Prev. 2008 May;17(5):1195-202.
3. Blom HJ and Smulders Y, J Inherit Metab Dis. 2011 Feb;34(1):75-81. doi: 10.1007/s10545-010-9177-4. Epub 2010 Sep 4.
4. Cheng H, etal., Mol Cell Biochem. 2015 Sep;407(1-2):51-6. doi: 10.1007/s11010-015-2453-8. Epub 2015 Jun 5.
5. Doolin MT, etal., Am J Hum Genet 2002 Nov;71(5):1222-6. Epub 2002 Oct 09.
6. Fong CS, etal., Clin Chim Acta. 2011 Jan 30;412(3-4):332-8. Epub 2010 Nov 8.
7. Gast A, etal., Leukemia. 2007 Feb;21(2):320-5. Epub 2006 Nov 30.
8. Gemmati D, etal., Cancer Epidemiol Biomarkers Prev. 2004 May;13(5):787-94.
9. Jiang Y, etal., Cell Biochem Biophys. 2011 Sep 24.
10. Kim HN, etal., Leuk Res. 2009 Jan;33(1):82-7. doi: 10.1016/j.leukres.2008.07.026. Epub 2008 Sep 6.
11. Kwak SY, etal., Anticancer Res. 2008 Sep-Oct;28(5A):2807-11.
12. Lautner-Csorba O, etal., PLoS One. 2013 Aug 5;8(8):e69843. doi: 10.1371/journal.pone.0069843. Print 2013.
13. Lima CS, etal., Leuk Res. 2008 Mar;32(3):401-5. Epub 2007 Jul 25.
14. MGD data from the GO Consortium
15. Miriuka SG, etal., Transpl Int. 2005 Jan;18(1):29-35.
16. Ohnami S, etal., Gastroenterology. 2008 Aug;135(2):477-88. Epub 2008 Apr 18.
17. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
18. OMIM Disease Annotation Pipeline
19. Pietrzyk JJ, etal., J Appl Genet. 2003;44(1):111-3.
20. RGD automated import pipeline
21. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
22. RGD automated import pipeline for gene-chemical interactions
23. Suzuki T, etal., Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2742-7.
24. Watkins D and Rosenblatt DS, J Inherit Metab Dis. 2012 Jul;35(4):665-70. doi: 10.1007/s10545-011-9418-1. Epub 2011 Nov 23.
25. Watkins D, etal., Am J Hum Genet. 2002 Jul;71(1):143-53. Epub 2002 May 30.
26. Wiltshire EJ, etal., Pediatr Diabetes. 2008 Aug;9(4 Pt 2):348-53.
27. Zavadakova P, etal., Hum Mutat. 2005 Mar;25(3):239-47.
28. Zhao JY, etal., Circulation. 2012 Jan 24;125(3):482-90. doi: 10.1161/CIRCULATIONAHA.111.050245. Epub 2011 Dec 16.
Additional References at PubMed
PMID:9501215   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:12520002   PMID:14610273   PMID:15329828   PMID:16141072   PMID:16141073   PMID:17369066  
PMID:18221906   PMID:18413293   PMID:18799693   PMID:19158324   PMID:19521500   PMID:21677750   PMID:21873635   PMID:24074862   PMID:24800750   PMID:26166573   PMID:29492317   PMID:30024025  
PMID:31537252   PMID:32257815   PMID:32968282   PMID:34140513   PMID:34702858   PMID:34957089  


Genomics

Comparative Map Data
Mtrr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391368,708,899 - 68,730,288 (-)NCBIGRCm39mm39
GRCm39 Ensembl1368,708,899 - 68,730,268 (-)Ensembl
GRCm381368,560,780 - 68,582,169 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1368,560,780 - 68,582,149 (-)EnsemblGRCm38mm10GRCm38
MGSCv371368,699,657 - 68,720,998 (-)NCBIGRCm37mm9NCBIm37
MGSCv361369,028,151 - 69,049,492 (-)NCBImm8
Celera1370,920,592 - 70,941,889 (-)NCBICelera
Cytogenetic Map13B3NCBI
cM Map1335.54NCBI
MTRR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3857,850,859 - 7,901,113 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl57,851,186 - 7,906,025 (+)EnsemblGRCh38hg38GRCh38
GRCh3757,869,261 - 7,901,226 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3657,922,217 - 7,954,237 (+)NCBINCBI36hg18NCBI36
Build 3457,922,216 - 7,954,233NCBI
Celera57,910,259 - 7,942,243 (+)NCBI
Cytogenetic Map5p15.31NCBI
HuRef57,850,954 - 7,882,932 (+)NCBIHuRef
CHM1_157,869,302 - 7,901,279 (+)NCBICHM1_1
T2T-CHM13v2.057,808,272 - 7,840,236 (+)NCBI
Mtrr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2134,866,991 - 34,899,425 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl134,867,089 - 34,899,425 (+)Ensembl
Rnor_6.0137,743,089 - 37,774,485 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl137,743,147 - 37,774,015 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0139,124,730 - 39,156,109 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4175,086,219 - 5,118,086 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1175,087,203 - 5,117,405 (+)NCBI
Celera133,436,562 - 33,468,429 (+)NCBICelera
Cytogenetic Map1p11NCBI
Mtrr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555045,413,586 - 5,435,645 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555045,412,290 - 5,435,409 (+)NCBIChiLan1.0ChiLan1.0
MTRR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.158,017,373 - 8,049,322 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl58,017,403 - 8,049,322 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v058,195,868 - 8,228,071 (+)NCBIMhudiblu_PPA_v0panPan3
MTRR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1346,068,572 - 6,119,580 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl346,070,046 - 6,098,312 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3410,576,595 - 10,608,261 (-)NCBI
ROS_Cfam_1.0345,974,025 - 6,005,680 (-)NCBI
ROS_Cfam_1.0 Ensembl345,974,050 - 6,005,641 (-)Ensembl
UMICH_Zoey_3.1346,023,818 - 6,055,451 (-)NCBI
UNSW_CanFamBas_1.0346,004,603 - 6,036,228 (-)NCBI
UU_Cfam_GSD_1.0346,217,429 - 6,249,109 (-)NCBI
Mtrr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213238,993,011 - 239,023,047 (-)NCBI
SpeTri2.0NW_004936643379,790 - 410,034 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTRR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1674,245,224 - 74,270,802 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11674,245,214 - 74,270,828 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21680,297,640 - 80,323,444 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MTRR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.147,461,521 - 7,493,032 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl47,461,526 - 7,493,840 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606421,124,251 - 21,155,756 (-)NCBIVero_WHO_p1.0
Mtrr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247515,445,241 - 5,469,657 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247515,445,274 - 5,469,386 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
Mtrr  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371368,704,054 - 68,705,006UniSTSGRCm37
MGSCv371368,707,773 - 68,708,938UniSTSGRCm37
Celera1370,925,000 - 70,925,954UniSTS
Celera1370,928,709 - 70,929,874UniSTS
Cytogenetic Map13B3UniSTS
cM Map1341.0UniSTS
cM Map1341.0UniSTS
D10Mit157.2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D1UniSTS
Cytogenetic Map16B4UniSTS
Cytogenetic Map18E2UniSTS
Cytogenetic Map4C3UniSTS
Cytogenetic Map7B2UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map14E2.2UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map3BUniSTS
Cytogenetic Map8C1UniSTS
Cytogenetic Map18A2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8E2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map18B1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map14C2UniSTS
Cytogenetic Map6A1UniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map13D2.1UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map17E3UniSTS
Cytogenetic Map11B3UniSTS
Cytogenetic Map1H4UniSTS
Cytogenetic Map6A3UniSTS
Cytogenetic Map5E4-E5UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map13DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map14D1UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic MapXDUniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map1H2.3UniSTS
Cytogenetic Map7A2UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map15D2UniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map16B2UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map1C4UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9F3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map9A4UniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map1A5UniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map6G1UniSTS
Cytogenetic MapXA2UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map5E2UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map9BUniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map10A4UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map18A1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map1C2UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map1BUniSTS
Cytogenetic Map17A3.1UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map4B1UniSTS
Cytogenetic Map15A2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic Map4A3UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map8A1UniSTS
Cytogenetic Map8A1.1UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map10B1UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map4A1UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map17CUniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map5E3UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map14C1UniSTS
Cytogenetic Map14E5UniSTS
Cytogenetic Map10CUniSTS
Cytogenetic Map18B2UniSTS
Cytogenetic Map2F1UniSTS
Cytogenetic Map10D3UniSTS
Cytogenetic Map17A2UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map17B2UniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map13C3UniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map15E3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXE3UniSTS
Cytogenetic Map4C4UniSTS
Cytogenetic Map3E3UniSTS
Cytogenetic Map11A4UniSTS
Cytogenetic Map4C5UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map7E1UniSTS
Cytogenetic Map5D-E1UniSTS
Cytogenetic Map5B3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map5A2UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map17E4UniSTS
Cytogenetic Map1G2UniSTS
Cytogenetic Map15B3.1UniSTS
Cytogenetic Map12EUniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map6A3.3UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map4D2.1UniSTS
Cytogenetic Map4A5UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map1E3-E4UniSTS
Cytogenetic Map9F1-F3UniSTS
Cytogenetic Map1C1.1UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map12A2UniSTS
Cytogenetic Map17A3-BUniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map14A3UniSTS
Cytogenetic Map5G1.1UniSTS
Cytogenetic MapXF2-F4UniSTS
Cytogenetic Map7D2UniSTS
Cytogenetic Map2F3UniSTS
Cytogenetic Map10A3UniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map9F1-F2UniSTS
Cytogenetic Map13A3.2UniSTS
Cytogenetic Map10A2UniSTS
Cytogenetic Map1C1UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map12D3UniSTS
Cytogenetic Map1A3-A5UniSTS
Cytogenetic Map2A2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic MapXA3.3UniSTS
Cytogenetic Map16A-B1UniSTS
Cytogenetic Map1D2.3UniSTS
Cytogenetic Map6B2.3UniSTS
Cytogenetic Map2G3UniSTS
Cytogenetic MapXA2-A3.1UniSTS
Cytogenetic Map9A5.3UniSTS
Cytogenetic Map14A2-BUniSTS
Cytogenetic Map8E1-E2UniSTS
Cytogenetic Map8A3UniSTS
Cytogenetic Map1G3-H1UniSTS
Cytogenetic Map8B3-C1UniSTS
Cytogenetic Map19C1UniSTS
Cytogenetic Map8C5UniSTS
Cytogenetic Map8A4UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map14E4UniSTS
Cytogenetic Map4D2.2UniSTS
Cytogenetic MapXF5UniSTS
cM Map1040.0UniSTS
Whitehead Genetic1033.9UniSTS
Mtrr  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381368,568,896 - 68,570,061UniSTSGRCm38
MGSCv371368,707,773 - 68,708,938UniSTSGRCm37
Celera1370,928,709 - 70,929,874UniSTS
Cytogenetic Map13B3UniSTS
cM Map1341.0UniSTS
Mtrr  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381368,565,177 - 68,566,129UniSTSGRCm38
MGSCv371368,704,054 - 68,705,006UniSTSGRCm37
Celera1370,925,000 - 70,925,954UniSTS
Cytogenetic Map13B3UniSTS


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884393Humsd7_mhumerus midshaft diameter 7, 16 week (mouse)13395000076048119Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
4142009Pregq3_mpregnancy QTL 3 (mouse)Not determined132061551272385189Mouse
1301299Sluc23_msusceptibility to lung cancer 23 (mouse)Not determined133492194368922081Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133606090896239162Mouse
1357587Pfat3_mpredicted fat percentage 3 (mouse)Not determined133610153070101640Mouse
1301734Acsns2_mAngiostrongylus costaricensis nematode susceptibility 2 (mouse)Not determined133610153070101640Mouse
1300561Heal7_mwound healing/regeneration 7 (mouse)Not determined133614482070144904Mouse
1300862Cfbw5_mcystic fibrosis body weight 5 (mouse)Not determined133872035872720517Mouse
1300985Bmd13_mbone mineral density 13 (mouse)Not determined133962924973629397Mouse
1302157Bwem2_mbody weight day 30 males 2 (mouse)Not determined133962924973629397Mouse
1301801Cpfd5_mcerebellum pattern fissures (mouse)Not determined133962924973629397Mouse
15039353Nmrs35_mNAFLD-associated magnetic resonance shift 35 (mouse)134058825374588253Mouse
1300668Pas10_mpulmonary adenoma susceptibility 10 (mouse)Not determined134148904275489158Mouse
4142331Bxs6_mBXSB/MpJ autoimmune nephritis 6 (mouse)Not determined4521044283744746Mouse
10412109Bxs7_mBXSB/MpJ autoimmune nephritis 7 (mouse)Not determined134521044283744746Mouse
26884396Humsd4_mhumerus midshaft diameter 4, 10 week (mouse)134785347673148119Mouse
4142372Moo2_mmodifier of Odc2 (mouse)Not determinedX5031841184318559Mouse
1301666Eae13_msusceptibility to experimental allergic encephalomyelitis 13 (mouse)Not determined135031841184318559Mouse
1300573Elsgp2_melevated serum gp70 2 (mouse)Not determined135061682884617027Mouse
14746975Manh74_mmandible shape 74 (mouse)135247726986477269Mouse
1302073Pgct1_mprimordial germ cell tumor locus 1 (mouse)Not determined135382078387820897Mouse
1357563Bmch6_mbone mechanical trait 6 (mouse)Not determined135538498089385140Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55720354112431103Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55720354112431103Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55720354112431103Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55720354112431103Mouse
1558850Sgp3_mserum gp70 production 3 (mouse)Not determined135647045676971314Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356470456105422186Mouse
1357553Cia28_mcollagen induced arthritis 28 (mouse)Not determined135662924996239162Mouse
10412163Wra1_mwheel running activity 1 (mouse)Not determined135913260093132738Mouse
1300941Skl6_mskeletal size (tail length) 6 (mouse)Not determined136425082198250945Mouse
1301949Skull20_mskull morphology 20 (mouse)Not determined136425082198250945Mouse
1301445Listr2_mlisteriosis resistance 2 (mouse)Not determined1366744601100744746Mouse
1301593Heal8_mwound healing/regeneration 8 (mouse)Not determined1368053999102054119Mouse
14696726Kidrq3_mkidney weight, right QTL 3 (mouse)1368217066102217066Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:490
Count of miRNA genes:343
Interacting mature miRNAs:399
Transcripts:ENSMUST00000045827
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001308475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_172480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_131892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006517179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006517181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006517182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036157959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK028628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC025942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC031565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC066796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ077698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT033781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000045827   ⟹   ENSMUSP00000039810
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1368,708,899 - 68,730,240 (-)Ensembl
GRCm38.p6 Ensembl1368,560,780 - 68,582,121 (-)Ensembl
RefSeq Acc Id: ENSMUST00000220544   ⟹   ENSMUSP00000152659
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1368,712,268 - 68,714,335 (-)Ensembl
GRCm38.p6 Ensembl1368,564,149 - 68,566,216 (-)Ensembl
RefSeq Acc Id: ENSMUST00000220973   ⟹   ENSMUSP00000152561
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1368,727,665 - 68,730,059 (-)Ensembl
GRCm38.p6 Ensembl1368,579,546 - 68,581,940 (-)Ensembl
RefSeq Acc Id: ENSMUST00000221259   ⟹   ENSMUSP00000152593
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1368,727,741 - 68,730,213 (-)Ensembl
GRCm38.p6 Ensembl1368,579,622 - 68,582,094 (-)Ensembl
RefSeq Acc Id: ENSMUST00000221800
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1368,728,203 - 68,730,219 (-)Ensembl
GRCm38.p6 Ensembl1368,580,084 - 68,582,100 (-)Ensembl
RefSeq Acc Id: ENSMUST00000222107   ⟹   ENSMUSP00000152837
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1368,723,242 - 68,730,268 (-)Ensembl
GRCm38.p6 Ensembl1368,575,123 - 68,582,149 (-)Ensembl
RefSeq Acc Id: ENSMUST00000223055
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1368,727,591 - 68,730,013 (-)Ensembl
GRCm38.p6 Ensembl1368,579,472 - 68,581,894 (-)Ensembl
RefSeq Acc Id: ENSMUST00000223101   ⟹   ENSMUSP00000152884
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1368,709,482 - 68,730,232 (-)Ensembl
GRCm38.p6 Ensembl1368,561,363 - 68,582,113 (-)Ensembl
RefSeq Acc Id: ENSMUST00000223398   ⟹   ENSMUSP00000152387
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1368,709,482 - 68,730,223 (-)Ensembl
GRCm38.p6 Ensembl1368,561,363 - 68,582,104 (-)Ensembl
RefSeq Acc Id: NM_001308475   ⟹   NP_001295404
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391368,708,899 - 68,730,223 (-)NCBI
GRCm381368,560,780 - 68,582,104 (-)NCBI
Sequence:
RefSeq Acc Id: NM_172480   ⟹   NP_766068
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391368,708,899 - 68,730,288 (-)NCBI
GRCm381368,560,780 - 68,582,169 (-)NCBI
MGSCv371368,699,657 - 68,720,998 (-)RGD
Celera1370,920,592 - 70,941,889 (-)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_131892
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391368,708,899 - 68,730,288 (-)NCBI
GRCm381368,560,780 - 68,582,169 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006517179   ⟹   XP_006517242
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391368,709,400 - 68,730,201 (-)NCBI
GRCm381368,561,281 - 68,582,058 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006517181   ⟹   XP_006517244
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391368,709,400 - 68,730,273 (-)NCBI
GRCm381368,561,281 - 68,582,089 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006517182   ⟹   XP_006517245
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391368,709,400 - 68,730,177 (-)NCBI
GRCm381368,561,281 - 68,582,058 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036157959   ⟹   XP_036013852
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391368,709,400 - 68,730,273 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_766068   ⟸   NM_172480
- UniProtKB: Q8C1A3 (UniProtKB/Swiss-Prot),   A0A0R4J0G9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006517244   ⟸   XM_006517181
- Peptide Label: isoform X1
- UniProtKB: Q8C1A3 (UniProtKB/Swiss-Prot),   A0A0R4J0G9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006517245   ⟸   XM_006517182
- Peptide Label: isoform X1
- UniProtKB: Q8C1A3 (UniProtKB/Swiss-Prot),   A0A0R4J0G9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006517242   ⟸   XM_006517179
- Peptide Label: isoform X1
- UniProtKB: Q8C1A3 (UniProtKB/Swiss-Prot),   A0A0R4J0G9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001295404   ⟸   NM_001308475
- UniProtKB: Q8C1A3 (UniProtKB/Swiss-Prot),   A0A0R4J0G9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000152387   ⟸   ENSMUST00000223398
RefSeq Acc Id: ENSMUSP00000152884   ⟸   ENSMUST00000223101
RefSeq Acc Id: ENSMUSP00000039810   ⟸   ENSMUST00000045827
RefSeq Acc Id: ENSMUSP00000152837   ⟸   ENSMUST00000222107
RefSeq Acc Id: ENSMUSP00000152593   ⟸   ENSMUST00000221259
RefSeq Acc Id: ENSMUSP00000152561   ⟸   ENSMUST00000220973
RefSeq Acc Id: ENSMUSP00000152659   ⟸   ENSMUST00000220544
RefSeq Acc Id: XP_036013852   ⟸   XM_036157959
- Peptide Label: isoform X1
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8C1A3-F1-model_v2 AlphaFold Q8C1A3 1-696 view protein structure

Promoters
RGD ID:8680750
Promoter ID:EPDNEW_M18405
Type:initiation region
Name:Mtrr_1
Description:Mus musculus 5-methyltetrahydrofolate-homocysteine methyltransferasereductase , transcript variant 3, non-coding RNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381368,582,124 - 68,582,184EPDNEW
RGD ID:6824171
Promoter ID:MM_KWN:14606
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B6
Transcripts:NM_172480,   UC007RBZ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361368,721,601 - 68,722,101 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1891037 AgrOrtholog
Ensembl Genes ENSMUSG00000034617 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000039810 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000152387 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000152561 UniProtKB/TrEMBL
  ENSMUSP00000152593 UniProtKB/TrEMBL
  ENSMUSP00000152659 UniProtKB/TrEMBL
  ENSMUSP00000152837 UniProtKB/TrEMBL
  ENSMUSP00000152884 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000045827 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000220544 UniProtKB/TrEMBL
  ENSMUST00000220973 UniProtKB/TrEMBL
  ENSMUST00000221259 UniProtKB/TrEMBL
  ENSMUST00000222107 UniProtKB/TrEMBL
  ENSMUST00000223101 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000223398 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.20.990.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.360 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.80 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CysJ-like_FAD-binding UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAD-bd_FR_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavdoxin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavodoxin/NO_synth UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavoprot_Pyr_Nucl_cyt_Rdtase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavoprotein-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FNR_nucleotide-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NADPH_Cyt_P450_Rdtase_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OxRdtase_FAD/NAD-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Riboflavin_synthase-like_b-brl UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:210009 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1891037 ENTREZGENE
NCBI Gene 210009 ENTREZGENE
Pfam FAD_binding_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavodoxin_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD_binding_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB MTRR RGD
PhenoGen Mtrr PhenoGen
PRINTS FLAVODOXIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FPNCR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE FAD_FR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FLAVODOXIN_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52218 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52343 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF63380 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J0G9 ENTREZGENE, UniProtKB/TrEMBL
  A0A1Y7VJV6_MOUSE UniProtKB/TrEMBL
  A0A1Y7VKC5_MOUSE UniProtKB/TrEMBL
  A0A1Y7VKD9_MOUSE UniProtKB/TrEMBL
  A0A1Y7VLV0_MOUSE UniProtKB/TrEMBL
  A0A1Y7VM78_MOUSE UniProtKB/TrEMBL
  MTRR_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q3U2C6 UniProtKB/Swiss-Prot
  Q8R0Y3 UniProtKB/Swiss-Prot