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Gene: ZNF426 (zinc finger protein 426) Homo sapiens
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Symbol: ZNF426
Name: zinc finger protein 426
Description: Kaposi's sarcoma-associated herpesvirus (KSHV) can be reactivated from latency by the viral protein RTA. The protein encoded by this gene is a zinc finger transcriptional repressor that interacts with RTA to modulate RTA-mediated reactivation of KSHV. While the encoded protein can repress KSHV reactivation, RTA can induce degradation of this protein through the ubiquitin-proteasome pathway to overcome the repression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CTC-543D15.7; K-RBP; MGC2663
Orthologs:
Mus musculus (house mouse) : Zfp426 (zinc finger protein 426)  MGI  Alliance
Rattus norvegicus (Norway rat) : Zfp426 (zinc finger protein 426)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : ZNF426 (zinc finger protein 426)
Canis lupus familiaris (dog) : LOC100684878 (zinc finger protein 426)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38199,523,223 - 9,538,865 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37199,638,667 - 9,649,638 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36199,499,667 - 9,510,303 (-)NCBINCBI36hg18NCBI36
Build 34199,499,682 - 9,510,303NCBI
Celera199,534,129 - 9,544,758 (-)NCBI
Cytogenetic Map19p13.2NCBI
HuRef199,219,651 - 9,230,281 (-)NCBIHuRef
CHM1_1199,633,520 - 9,648,935 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on ZNF426
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318534
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.