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Gene: ZNF426 (zinc finger protein 426) Homo sapiens
Symbol: ZNF426
Name: zinc finger protein 426
Description: Kaposi's sarcoma-associated herpesvirus (KSHV) can be reactivated from latency by the viral protein RTA. The protein encoded by this gene is a zinc finger transcriptional repressor that interacts with RTA to modulate RTA-mediated reactivation of KSHV. While the encoded protein can repress KSHV reactivation, RTA can induce degradation of this protein through the ubiquitin-proteasome pathway to overcome the repression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CTC-543D15.7; K-RBP; MGC2663
Mus musculus (house mouse) : Zfp426 (zinc finger protein 426)  MGI  Alliance
Rattus norvegicus (Norway rat) : Zfp426 (zinc finger protein 426)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : ZNF426 (zinc finger protein 426)
Canis lupus familiaris (dog) : LOC100684878 (zinc finger protein 426)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38199,523,223 - 9,538,865 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37199,638,667 - 9,649,638 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36199,499,667 - 9,510,303 (-)NCBINCBI36hg18NCBI36
Build 34199,499,682 - 9,510,303NCBI
Celera199,534,129 - 9,544,758 (-)NCBI
Cytogenetic Map19p13.2NCBI
HuRef199,219,651 - 9,230,281 (-)NCBIHuRef
CHM1_1199,633,520 - 9,648,935 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ZNF426
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318534
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.