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Gene: Tsen15 (tRNA splicing endonuclease subunit 15) Mus musculus
Symbol: Tsen15
Name: tRNA splicing endonuclease subunit 15
Description: Predicted to have nucleic acid binding activity and tRNA-intron endonuclease activity. Predicted to be involved in mRNA processing and tRNA splicing, via endonucleolytic cleavage and ligation. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia. Orthologous to human TSEN15 (tRNA splicing endonuclease subunit 15); PARTICIPATES IN tRNA maturation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5730449L18Rik; AL023077; Sen15; tRNA splicing endonuclease 15 homolog; tRNA-intron endonuclease Sen15; tRNA-splicing endonuclease subunit Sen15
Homo sapiens (human) : TSEN15 (tRNA splicing endonuclease subunit 15)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tsen15 (tRNA splicing endonuclease subunit 15)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tsen15 (tRNA splicing endonuclease subunit 15)
Pan paniscus (bonobo/pygmy chimpanzee) : TSEN15 (tRNA splicing endonuclease subunit 15)
Canis lupus familiaris (dog) : TSEN15 (tRNA splicing endonuclease subunit 15)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tsen15 (tRNA splicing endonuclease subunit 15)
Sus scrofa (pig) : TSEN15 (tRNA splicing endonuclease subunit 15)
Chlorocebus sabaeus (African green monkey) : TSEN15 (tRNA splicing endonuclease subunit 15)
Heterocephalus glaber (naked mole-rat) : Tsen15 (tRNA splicing endonuclease subunit 15)
more info ...
Related Pseudogenes: Gm5874  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1152,370,735 - 152,386,688 (-)EnsemblGRCm38mm10GRCm38
GRCm381152,370,735 - 152,386,682 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371154,217,865 - 154,233,812 (-)NCBIGRCm37mm9NCBIm37
MGSCv361154,132,957 - 154,148,900 (-)NCBImm8
Celera1154,791,904 - 154,807,754 (-)NCBICelera
Cytogenetic Map1G2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Tsen15
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318441
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.