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Gene: CLDN8 (claudin 8) Homo sapiens
Symbol: CLDN8
Name: claudin 8
RGD ID: 1318427
Description: Predicted to have identical protein binding activity. Predicted to be involved in bicellular tight junction assembly and calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules. Localizes to endoplasmic reticulum and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: claudin-8; epididymis secretory protein Li 79; HEL-S-79
Mus musculus (house mouse) : Cldn8 (claudin 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cldn8 (claudin 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cldn8 (claudin 8)
Pan paniscus (bonobo/pygmy chimpanzee) : CLDN8 (claudin 8)
Canis lupus familiaris (dog) : CLDN8 (claudin 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cldn8 (claudin 8)
Sus scrofa (pig) : CLDN8 (claudin 8)
Chlorocebus sabaeus (African green monkey) : CLDN8 (claudin 8)
Heterocephalus glaber (naked mole-rat) : Cldn8 (claudin 8)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2130,214,006 - 30,216,097 (-)EnsemblGRCh38hg38GRCh38
GRCh382130,214,006 - 30,216,097 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372131,586,324 - 31,588,469 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362130,508,201 - 30,510,189 (-)NCBINCBI36hg18NCBI36
Build 342130,508,200 - 30,510,189NCBI
Celera2116,769,465 - 16,771,610 (-)NCBI
Cytogenetic Map21q22.11NCBI
HuRef2116,995,205 - 16,997,350 (-)NCBIHuRef
CHM1_12131,147,901 - 31,150,046 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on CLDN8
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318427
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.