Arhgap5 (Rho GTPase activating protein 5) - Rat Genome Database

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Gene: Arhgap5 (Rho GTPase activating protein 5) Mus musculus
Analyze
Symbol: Arhgap5
Name: Rho GTPase activating protein 5
RGD ID: 1318316
MGI Page MGI
Description: Predicted to enable GTPase activator activity and SH2 domain binding activity. Acts upstream of or within several processes, including positive regulation of epithelial cell migration; positive regulation of mesenchymal cell proliferation; and regulation of cell size. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human ARHGAP5 (Rho GTPase activating protein 5).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: p190; p190-; p190-B; p190B; rho GTPase-activating protein 5; rho-type GTPase-activating protein 5
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391252,550,555 - 52,618,761 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1252,550,755 - 52,618,758 (+)EnsemblGRCm39 Ensembl
GRCm381252,503,763 - 52,571,978 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1252,503,972 - 52,571,975 (+)EnsemblGRCm38mm10GRCm38
MGSCv371253,617,064 - 53,668,839 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361253,437,697 - 53,489,472 (+)NCBIMGSCv36mm8
Celera1253,816,020 - 53,871,323 (+)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1222.16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,6-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (EXP)
4-vinylcyclohexene dioxide  (EXP)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcitriol  (ISO)
cantharidin  (EXP)
chloroprene  (ISO)
cisplatin  (ISO)
clobetasol  (EXP)
clofibrate  (EXP)
cocaine  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cyclosporin A  (EXP)
DDT  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
hydralazine  (ISO)
irinotecan  (ISO)
ketamine  (ISO)
lipopolysaccharide  (ISO)
methidathion  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
miconazole  (EXP)
N-nitrosodiethylamine  (EXP)
nickel sulfate  (ISO)
panobinostat  (ISO)
paracetamol  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (EXP,ISO)
pirinixic acid  (EXP)
rac-lactic acid  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (EXP)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP)
sunitinib  (ISO)
tetrachloroethene  (EXP)
thimerosal  (ISO)
trichostatin A  (ISO)
triptonide  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. P190-B, a Rho-GTPase-activating protein, is differentially expressed in terminal end buds and breast cancer. Chakravarty G, etal., Cell Growth Differ. 2000 Jul;11(7):343-54.
2. MiR-744 functions as a proto-oncogene in nasopharyngeal carcinoma progression and metastasis via transcriptional control of ARHGAP5. Fang Y, etal., Oncotarget. 2015 May 30;6(15):13164-75.
3. Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression. Heckman-Stoddard BM, etal., Breast Cancer Res. 2009;11(4):R61. doi: 10.1186/bcr2352. Epub 2009 Aug 24.
4. P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasis. McHenry PR, etal., Breast Cancer Res. 2010;12(5):R73. doi: 10.1186/bcr2643. Epub 2010 Sep 22.
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:9121432   PMID:9838117   PMID:10349636   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11544199   PMID:12015964   PMID:12466851  
PMID:12477932   PMID:12637587   PMID:12705864   PMID:12904583   PMID:14610273   PMID:14681479   PMID:15169898   PMID:15328020   PMID:16141072   PMID:16141073   PMID:16469769   PMID:16602821  
PMID:16919269   PMID:17662267   PMID:17953485   PMID:19463158   PMID:19713466   PMID:21873635   PMID:21945077   PMID:23563238   PMID:24472646   PMID:25737280   PMID:28176763   PMID:31040226  
PMID:32325033   PMID:33863978  


Genomics

Comparative Map Data
Arhgap5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391252,550,555 - 52,618,761 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1252,550,755 - 52,618,758 (+)EnsemblGRCm39 Ensembl
GRCm381252,503,763 - 52,571,978 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1252,503,972 - 52,571,975 (+)EnsemblGRCm38mm10GRCm38
MGSCv371253,617,064 - 53,668,839 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361253,437,697 - 53,489,472 (+)NCBIMGSCv36mm8
Celera1253,816,020 - 53,871,323 (+)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1222.16NCBI
ARHGAP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381432,077,304 - 32,159,728 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1432,076,114 - 32,159,728 (+)EnsemblGRCh38hg38GRCh38
GRCh371432,546,510 - 32,628,934 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361431,616,246 - 31,698,685 (+)NCBINCBI36Build 36hg18NCBI36
Build 341431,616,247 - 31,694,095NCBI
Celera1412,412,908 - 12,495,351 (+)NCBICelera
Cytogenetic Map14q12NCBI
HuRef1412,663,810 - 12,746,250 (+)NCBIHuRef
CHM1_11432,546,410 - 32,628,781 (+)NCBICHM1_1
T2T-CHM13v2.01426,274,927 - 26,357,362 (+)NCBIT2T-CHM13v2.0
Arhgap5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8675,711,199 - 75,774,636 (+)NCBIGRCr8
mRatBN7.2669,975,904 - 70,039,299 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl669,976,214 - 70,037,660 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx670,400,553 - 70,463,444 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0670,707,197 - 70,770,089 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0670,146,761 - 70,209,656 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0673,345,129 - 73,408,304 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl673,345,392 - 73,405,880 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0682,905,983 - 82,970,518 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4672,685,231 - 72,693,052 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1672,688,353 - 72,735,913 (+)NCBI
Celera668,851,685 - 68,859,506 (+)NCBICelera
Cytogenetic Map6q23NCBI
Arhgap5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540928,627,176 - 28,705,893 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540928,627,176 - 28,682,302 (-)NCBIChiLan1.0ChiLan1.0
ARHGAP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21533,393,901 - 33,487,196 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11432,610,399 - 32,702,106 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01412,844,042 - 12,934,411 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11431,036,491 - 31,125,349 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1431,036,511 - 31,125,349 (+)Ensemblpanpan1.1panPan2
ARHGAP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1811,190,663 - 11,269,353 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl811,204,696 - 11,267,086 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha811,052,457 - 11,131,162 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0811,292,865 - 11,371,626 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl811,293,336 - 11,370,667 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1810,977,322 - 11,056,021 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0811,057,909 - 11,136,737 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0811,336,405 - 11,415,092 (+)NCBIUU_Cfam_GSD_1.0
Arhgap5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864043,056,223 - 43,122,569 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364946,562,069 - 6,623,175 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364946,562,092 - 6,624,015 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGAP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl767,494,941 - 67,594,197 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1767,494,237 - 67,631,461 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2772,356,323 - 72,370,515 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGAP5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1248,914,485 - 8,986,498 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl248,928,252 - 8,988,302 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606218,559,918 - 18,566,253 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgap5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624820305,475 - 381,058 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624820302,000 - 381,043 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Arhgap5
2192 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:95
Count of miRNA genes:89
Interacting mature miRNAs:93
Transcripts:ENSMUST00000110725
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142234Tmc1m3_mTmc1 modifier 3 (mouse)Not determined12541844077031203Mouse
27226753Femd7_mfemur midshaft diameter 7, 10 week (mouse)12955000084146774Mouse
13207568Tcq14_mtotal cholesterol QTL 14 (mouse)121166000197176774Mouse
13524839Ppiq10_mprepulse inhibition QTL 10 (mouse)121304319554945798Mouse
1558978Cplaq10_mcircadian period of locomotor activity 10 (mouse)Not determined121534102679040364Mouse
1301574Lmblgq5_mlimb length QTL 5 (mouse)Not determined121759644780956883Mouse
12904956Edlmmq10_mextensor digitorum longus muscle mass QTL 10 (mouse)121973983353739833Mouse
1302172Skts5_mskin tumor susceptibility 5 (mouse)Not determined122214886656149016Mouse
1301989Hdlq18_mHDL QTL 18 (mouse)Not determined122916068563160884Mouse
1300636Gct2_mgranulosa cell tumorigenesis 2 (mouse)Not determined122916068563160884Mouse
4141843Moen3_mmodifier of engrailed QTL 3 (mouse)Not determined122980158463801733Mouse
14747008Mancz10_mmandible centroid size 10 (mouse)122986352263863522Mouse
10402492Dipa8_mdrug induced psychomotor activation 8 (mouse)Not determined123493387268934019Mouse
1300818Bbaa10_mB.burgdorferi-associated arthritis 10 (mouse)Not determined123509100465511019Mouse
4142002Tbqt3_mtibia bone quality traits 3 (mouse)Not determined1235285496109936243Mouse
1357479Splwt1_mspleen weight 1 (mouse)Not determined124169317590887526Mouse

Markers in Region
AU014947  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381252,568,053 - 52,568,262UniSTSGRCm38
MGSCv371253,669,040 - 53,669,249UniSTSGRCm37
Celera1253,871,524 - 53,871,733UniSTS
Cytogenetic Map12C1UniSTS
cM Map1225.75UniSTS
Whitehead/MRC_RH22028.05UniSTS
Arhgap5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12C1UniSTS
cM Map1225.75UniSTS
cM Map1225.75UniSTS
UniSTS:236844  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381252,523,757 - 52,523,992UniSTSGRCm38
MGSCv371253,624,744 - 53,624,979UniSTSGRCm37
Celera1253,823,705 - 53,823,940UniSTS
Cytogenetic Map12C1UniSTS
cM Map1225.75UniSTS
Arhgap5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12C1UniSTS
cM Map1225.75UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001408721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001408722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001408723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001408724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_176796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_176797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC114002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC155819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK039081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK041016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK084663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK131622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC009135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC150823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM940854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU613221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF742308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO433888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U67160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000110725   ⟹   ENSMUSP00000106353
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1252,562,860 - 52,614,635 (+)Ensembl
GRCm38.p6 Ensembl1252,516,077 - 52,567,852 (+)Ensembl
RefSeq Acc Id: ENSMUST00000217820   ⟹   ENSMUSP00000151267
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1252,551,125 - 52,615,618 (+)Ensembl
GRCm38.p6 Ensembl1252,504,342 - 52,568,835 (+)Ensembl
RefSeq Acc Id: ENSMUST00000218755
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1252,550,755 - 52,592,422 (+)Ensembl
GRCm38.p6 Ensembl1252,503,972 - 52,545,639 (+)Ensembl
RefSeq Acc Id: ENSMUST00000219443   ⟹   ENSMUSP00000151809
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1252,550,799 - 52,618,758 (+)Ensembl
GRCm38.p6 Ensembl1252,504,016 - 52,571,975 (+)Ensembl
RefSeq Acc Id: NM_001408721   ⟹   NP_001395650
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,550,555 - 52,618,761 (+)NCBI
RefSeq Acc Id: NM_001408722   ⟹   NP_001395651
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,550,717 - 52,618,761 (+)NCBI
RefSeq Acc Id: NM_001408723   ⟹   NP_001395652
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,550,717 - 52,618,761 (+)NCBI
RefSeq Acc Id: NM_001408724   ⟹   NP_001395653
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,550,856 - 52,618,761 (+)NCBI
RefSeq Acc Id: NM_009706   ⟹   NP_033836
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,550,856 - 52,618,761 (+)NCBI
GRCm381252,516,077 - 52,567,852 (+)NCBI
MGSCv371253,617,064 - 53,668,839 (+)RGD
Celera1253,816,020 - 53,871,323 (+)RGD
cM Map12 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_176796
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,550,856 - 52,618,761 (+)NCBI
RefSeq Acc Id: NR_176797
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,550,856 - 52,618,761 (+)NCBI
RefSeq Acc Id: NP_033836   ⟸   NM_009706
- Peptide Label: isoform 1
- UniProtKB: P97393 (UniProtKB/Swiss-Prot),   E9Q0L8 (UniProtKB/Swiss-Prot),   E9PYT0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000151267   ⟸   ENSMUST00000217820
RefSeq Acc Id: ENSMUSP00000106353   ⟸   ENSMUST00000110725
RefSeq Acc Id: ENSMUSP00000151809   ⟸   ENSMUST00000219443
RefSeq Acc Id: NP_001395650   ⟸   NM_001408721
- Peptide Label: isoform 1
- UniProtKB: P97393 (UniProtKB/Swiss-Prot),   E9PYT0 (UniProtKB/Swiss-Prot),   E9Q0L8 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001395651   ⟸   NM_001408722
- Peptide Label: isoform 1
- UniProtKB: P97393 (UniProtKB/Swiss-Prot),   E9PYT0 (UniProtKB/Swiss-Prot),   E9Q0L8 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001395652   ⟸   NM_001408723
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001395653   ⟸   NM_001408724
- Peptide Label: isoform 2
Protein Domains
FF   pG1 pseudoGTPase   pG2 pseudoGTPase   Rho-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97393-F1-model_v2 AlphaFold P97393 1-1501 view protein structure

Promoters
RGD ID:8678258
Promoter ID:EPDNEW_M17160
Type:initiation region
Name:Arhgap5_1
Description:Mus musculus Rho GTPase activating protein 5 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381252,503,942 - 52,504,002EPDNEW
RGD ID:6822731
Promoter ID:MM_KWN:11627
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   Kidney,   Liver,   Lung,   MEF_B6
Transcripts:ENSMUST00000110725
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361253,618,901 - 53,620,342 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1332637 AgrOrtholog
Ensembl Genes ENSMUSG00000035133 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000110725 ENTREZGENE
  ENSMUST00000110725.2 UniProtKB/Swiss-Prot
  ENSMUST00000217820.2 UniProtKB/TrEMBL
  ENSMUST00000219443 ENTREZGENE
  ENSMUST00000219443.2 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.10.440 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.555.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FF_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FF_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  pG1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP-FF1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP_pG1_pG2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP_pG2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:11855 UniProtKB/Swiss-Prot
MGD MGI:1332637 ENTREZGENE
NCBI Gene 11855 ENTREZGENE
PANTHER RHO GTPASE-ACTIVATING PROTEIN 190 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHO GTPASE-ACTIVATING PROTEIN 5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PF01846 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP-FF1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGAP_pG1_pG2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB ARHGAP5 RGD
PhenoGen Arhgap5 PhenoGen
PRINTS RASTRNSFRMNG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PG1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PG2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS51676 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHOGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RhoGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00441 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF81698 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1W2P6H9_MOUSE UniProtKB/TrEMBL
  B9EKC3_MOUSE UniProtKB/TrEMBL
  E9PYT0 ENTREZGENE
  E9Q0L8 ENTREZGENE
  P97393 ENTREZGENE
  Q3TQ76_MOUSE UniProtKB/TrEMBL
  Q3V2S0_MOUSE UniProtKB/TrEMBL
  RHG05_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary E9PYT0 UniProtKB/Swiss-Prot
  E9Q0L8 UniProtKB/Swiss-Prot