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Gene: DENND4C (DENN domain containing 4C) Homo sapiens
Symbol: DENND4C
Name: DENN domain containing 4C
Description: Exhibits Rab guanyl-nucleotide exchange factor activity. Predicted to be involved in cellular response to insulin stimulus and protein localization to plasma membrane. Localizes to the Golgi apparatus and cytosol; PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 2-methylcholine; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bA513M16.3; C9orf55; C9orf55B; chromosome 9 open reading frame 55; DENN domain-containing protein 4C; DENN/MADD domain containing 4A pseudogene; DENN/MADD domain containing 4C; DKFZp686I09113; FLJ20686; RAB10GEF
Mus musculus (house mouse) : Dennd4c (DENN/MADD domain containing 4C)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dennd4c (DENN domain containing 4C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dennd4c (DENN domain containing 4C)
Pan paniscus (bonobo/pygmy chimpanzee) : DENND4C (DENN domain containing 4C)
Canis lupus familiaris (dog) : DENND4C (DENN domain containing 4C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dennd4c (DENN domain containing 4C)
Sus scrofa (pig) : DENND4C (DENN domain containing 4C)
Chlorocebus sabaeus (green monkey) : DENND4C (DENN domain containing 4C)
Heterocephalus glaber (naked mole-rat) : Dennd4c (DENN domain containing 4C)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl919,230,435 - 19,373,545 (+)Ensembl
GRCh38919,230,693 - 19,374,281 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37919,230,763 - 19,374,137 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36919,280,749 - 19,364,139 (+)NCBINCBI36hg18NCBI36
Build 34919,288,065 - 19,362,856NCBI
Celera919,216,854 - 19,300,236 (+)NCBI
Cytogenetic Map9p22.1NCBI
HuRef919,192,829 - 19,335,696 (+)NCBIHuRef
CHM1_1919,230,600 - 19,374,066 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DENND4C
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318285
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-02-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.