Mocs1 (molybdenum cofactor synthesis 1) - Rat Genome Database

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Gene: Mocs1 (molybdenum cofactor synthesis 1) Mus musculus
Analyze
Symbol: Mocs1
Name: molybdenum cofactor synthesis 1
RGD ID: 1318259
MGI Page MGI
Description: Enables GTP 3',8'-cyclase activity; S-adenosyl-L-methionine binding activity; and cyclic pyranopterin monophosphate synthase activity. Involved in molybdopterin cofactor biosynthetic process. Predicted to be located in cytosol. Used to study molybdenum cofactor deficiency type A. Human ortholog(s) of this gene implicated in molybdenum cofactor deficiency type A. Orthologous to human MOCS1 (molybdenum cofactor synthesis 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 3110045D15Rik; AI043170; AW536397; molybdenum cofactor biosynthesis protein 1; molybdenum cofactor synthesis-step 1 proteins A and B
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391749,735,378 - 49,762,463 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1749,735,390 - 49,762,463 (+)EnsemblGRCm39 Ensembl
GRCm381749,428,350 - 49,455,435 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1749,428,362 - 49,455,435 (+)EnsemblGRCm38mm10GRCm38
MGSCv371749,567,689 - 49,594,755 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361748,917,808 - 48,920,997 (+)NCBIMGSCv36mm8
Celera1752,857,373 - 52,876,826 (+)NCBICelera
Cytogenetic Map17CNCBI
cM Map1725.45NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (ISO)
mitochondrion  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Cell biology of molybdenum. Mendel RR and Bittner F, Biochim Biophys Acta. 2006 Jul;1763(7):621-35. Epub 2006 May 12.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. Mutations in the molybdenum cofactor biosynthetic genes MOCS1, MOCS2, and GEPH. Reiss J and Johnson JL, Hum Mutat 2003 Jun;21(6):569-76.
9. Genomic structure and mutational spectrum of the bicistronic MOCS1 gene defective in molybdenum cofactor deficiency type A. Reiss J, etal., Hum Genet. 1998 Dec;103(6):639-44.
10. Mutations in a polycistronic nuclear gene associated with molybdenum cofactor deficiency. Reiss J, etal., Nat Genet. 1998 Sep;20(1):51-3.
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10917590   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12471057   PMID:12477932   PMID:14691545   PMID:15862276   PMID:16141072   PMID:16141073   PMID:16602821  
PMID:17236133   PMID:21267068   PMID:21677750   PMID:21873635   PMID:29222160   PMID:30550785   PMID:31996372  


Genomics

Comparative Map Data
Mocs1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391749,735,378 - 49,762,463 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1749,735,390 - 49,762,463 (+)EnsemblGRCm39 Ensembl
GRCm381749,428,350 - 49,455,435 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1749,428,362 - 49,455,435 (+)EnsemblGRCm38mm10GRCm38
MGSCv371749,567,689 - 49,594,755 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361748,917,808 - 48,920,997 (+)NCBIMGSCv36mm8
Celera1752,857,373 - 52,876,826 (+)NCBICelera
Cytogenetic Map17CNCBI
cM Map1725.45NCBI
MOCS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38639,904,170 - 39,934,462 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl639,899,578 - 39,934,551 (-)EnsemblGRCh38hg38GRCh38
GRCh37639,871,946 - 39,902,201 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36639,981,072 - 40,010,196 (-)NCBINCBI36Build 36hg18NCBI36
Celera641,425,262 - 41,455,518 (-)NCBICelera
Cytogenetic Map6p21.2NCBI
HuRef639,589,847 - 39,620,839 (-)NCBIHuRef
CHM1_1639,874,626 - 39,904,861 (-)NCBICHM1_1
T2T-CHM13v2.0639,730,595 - 39,761,764 (-)NCBIT2T-CHM13v2.0
Mocs1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8919,045,223 - 19,071,628 (-)NCBIGRCr8
mRatBN7.2911,547,533 - 11,573,935 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl911,547,531 - 11,567,790 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx920,050,514 - 20,070,761 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0925,116,683 - 25,136,930 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0923,500,264 - 23,520,999 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0913,493,705 - 13,513,972 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl913,493,709 - 13,513,960 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0912,426,594 - 12,452,999 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.496,759,531 - 6,779,930 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.196,760,110 - 7,013,161 (-)NCBI
Celera99,321,644 - 9,341,714 (-)NCBICelera
Cytogenetic Map9q12NCBI
Mocs1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554376,840,451 - 6,870,685 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554376,840,451 - 6,870,685 (-)NCBIChiLan1.0ChiLan1.0
MOCS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2554,396,925 - 54,426,657 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1650,263,478 - 50,296,374 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0639,489,310 - 39,519,012 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1640,799,858 - 40,829,346 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl640,799,858 - 40,829,346 (-)Ensemblpanpan1.1panPan2
MOCS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1128,802,506 - 8,837,242 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl128,779,428 - 8,837,452 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha128,834,241 - 8,870,254 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0129,279,672 - 9,315,694 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl129,280,934 - 9,315,905 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1128,814,238 - 8,850,260 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0128,884,790 - 8,920,816 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0128,990,878 - 9,026,925 (-)NCBIUU_Cfam_GSD_1.0
Mocs1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494644,189,065 - 44,217,172 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647619,743,024 - 19,775,300 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647619,743,052 - 19,771,132 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MOCS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl735,287,365 - 35,320,931 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1735,286,565 - 35,320,935 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2740,416,831 - 40,451,229 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MOCS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11732,224,211 - 32,252,244 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604439,897,722 - 39,927,070 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mocs1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475418,492,073 - 18,524,755 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475418,491,970 - 18,524,741 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mocs1
807 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4294
Count of miRNA genes:839
Interacting mature miRNAs:1125
Transcripts:ENSMUST00000024797, ENSMUST00000165390, ENSMUST00000172871, ENSMUST00000173033, ENSMUST00000173362, ENSMUST00000173430, ENSMUST00000174268, ENSMUST00000174647
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171841835752420983Mouse
26884379Skwq5_mskull length QTL 5, 5 week (mouse)173311897454107028Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171817541252178214Mouse
35673315Ari1_mantibody response to influenza 1, day 7, IgG2a+IgG2c (mouse)174731092654707028Mouse
1300885Mbis4_mMycobacterium bovis-induced systemic lupus erythematosus 4 (mouse)Not determined173517581770165926Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172862240662622654Mouse
4142192Obrq14_mobesity resistance QTL 14 (mouse)Not determined4901334052966424Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172781520961815209Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171842214152424327Mouse
26884428Cvht3_mcranial vault height 3, 5 week (mouse)174651092682407429Mouse
4141478Hbnr7_mHeligmosomoides bakeri nematode resistance 7 (mouse)Not determined4305118551739122Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171681972150819843Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172461275058612864Mouse
10755514Amzn2_manatomical modifier of Zfp423 2 (mouse)173596629469966424Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171914502553145025Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171746220851462345Mouse
10755525Lymph2_mlymphocyte differential 2 (mouse)173880562672805626Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171746220851462345Mouse
1300592Pcyts5_mplasmacytoma susceptibility 5 (mouse)Not determined173871288772712970Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171746220851462345Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3103350065033630Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172688497260885114Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171746220851462345Mouse
10755534Lymph4_mlymphocyte differential 4 (mouse)173880562672805626Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171702994351030078Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171681972150819843Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172640101252911704Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172605118560051352Mouse
12904951Smmq2_msoleus muscle mass QTL 2 (mouse)173678974370789743Mouse
4141319Hmtb8_mhemostasis and thrombosis rebleeding time 8 (mouse)Not determined4053444774534623Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172507658355712970Mouse
26884386Skwq13_mskull length QTL 13, 16 week (mouse)174371089153107028Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
15039324Nmrs48_mNAFLD-associated magnetic resonance shift 48 (mouse)174093918774939187Mouse
26884390Skwq9_mskull length QTL 9, 10 week (mouse)174371089167806995Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined173013255564132666Mouse

Markers in Region
AW536397  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381749,455,305 - 49,455,416UniSTSGRCm38
MGSCv371749,594,630 - 49,594,741UniSTSGRCm37
Celera1752,876,701 - 52,876,812UniSTS
Cytogenetic Map17CUniSTS
Whitehead/MRC_RH17602.46UniSTS
AI043170  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381749,455,305 - 49,455,406UniSTSGRCm38
MGSCv371749,594,630 - 49,594,731UniSTSGRCm37
Celera1752,876,701 - 52,876,802UniSTS
Cytogenetic Map17CUniSTS
Whitehead/MRC_RH17602.46UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_020042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_028464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006524680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006524681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006524682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC165258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF214016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF214024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK014178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC034066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC049914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC147411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC147412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC172067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE851067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN701969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000024797   ⟹   ENSMUSP00000024797
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1749,735,392 - 49,762,460 (+)Ensembl
GRCm38.p6 Ensembl1749,428,364 - 49,455,432 (+)Ensembl
Ensembl Acc Id: ENSMUST00000165390   ⟹   ENSMUSP00000132371
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1749,735,390 - 49,744,969 (+)Ensembl
GRCm38.p6 Ensembl1749,428,362 - 49,437,941 (+)Ensembl
Ensembl Acc Id: ENSMUST00000173033   ⟹   ENSMUSP00000133694
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1749,735,438 - 49,762,463 (+)Ensembl
GRCm38.p6 Ensembl1749,428,410 - 49,455,435 (+)Ensembl
Ensembl Acc Id: ENSMUST00000173362   ⟹   ENSMUSP00000134265
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1749,735,470 - 49,761,818 (+)Ensembl
GRCm38.p6 Ensembl1749,428,442 - 49,454,790 (+)Ensembl
Ensembl Acc Id: ENSMUST00000173430   ⟹   ENSMUSP00000133761
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1749,759,312 - 49,762,463 (+)Ensembl
GRCm38.p6 Ensembl1749,452,284 - 49,455,435 (+)Ensembl
Ensembl Acc Id: ENSMUST00000174268
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1749,740,224 - 49,742,560 (+)Ensembl
GRCm38.p6 Ensembl1749,433,196 - 49,435,532 (+)Ensembl
Ensembl Acc Id: ENSMUST00000174647   ⟹   ENSMUSP00000133713
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1749,735,470 - 49,761,818 (+)Ensembl
GRCm38.p6 Ensembl1749,428,442 - 49,454,790 (+)Ensembl
RefSeq Acc Id: NM_020042   ⟹   NP_064426
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391749,735,420 - 49,762,458 (+)NCBI
GRCm381749,428,364 - 49,455,430 (+)NCBI
MGSCv371749,567,689 - 49,594,755 (+)RGD
Celera1752,857,373 - 52,876,826 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_028464   ⟹   NP_082740
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391749,735,420 - 49,762,458 (+)NCBI
GRCm381749,428,364 - 49,455,430 (+)NCBI
MGSCv371749,567,689 - 49,594,755 (+)RGD
Celera1752,857,373 - 52,876,826 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006524680   ⟹   XP_006524743
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391749,735,378 - 49,762,463 (+)NCBI
GRCm381749,428,350 - 49,455,435 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006524681   ⟹   XP_006524744
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391749,746,544 - 49,762,463 (+)NCBI
GRCm381749,433,169 - 49,455,435 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006524682   ⟹   XP_006524745
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391749,756,128 - 49,762,463 (+)NCBI
GRCm381749,449,100 - 49,455,435 (+)NCBI
Sequence:
RefSeq Acc Id: NP_064426   ⟸   NM_020042
- Peptide Label: isoform 1
- UniProtKB: Q9JL32 (UniProtKB/Swiss-Prot),   Q8R058 (UniProtKB/Swiss-Prot),   B7ZWI5 (UniProtKB/Swiss-Prot),   B2RVW8 (UniProtKB/Swiss-Prot),   Q9JL33 (UniProtKB/Swiss-Prot),   Q5RKZ7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_082740   ⟸   NM_028464
- Peptide Label: isoform 2
- UniProtKB: Q5RKZ7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006524743   ⟸   XM_006524680
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006524744   ⟸   XM_006524681
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006524745   ⟸   XM_006524682
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSMUSP00000132371   ⟸   ENSMUST00000165390
Ensembl Acc Id: ENSMUSP00000133713   ⟸   ENSMUST00000174647
Ensembl Acc Id: ENSMUSP00000134265   ⟸   ENSMUST00000173362
Ensembl Acc Id: ENSMUSP00000133761   ⟸   ENSMUST00000173430
Ensembl Acc Id: ENSMUSP00000133694   ⟸   ENSMUST00000173033
Ensembl Acc Id: ENSMUSP00000024797   ⟸   ENSMUST00000024797
Protein Domains
Radical SAM core

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5RKZ7-F1-model_v2 AlphaFold Q5RKZ7 1-636 view protein structure

Promoters
RGD ID:13676378
Promoter ID:EPDNEW_M22338
Type:initiation region
Name:Mocs1_1
Description:Mus musculus molybdenum cofactor synthesis 1 , transcript variant2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381749,428,424 - 49,428,484EPDNEW
RGD ID:6828365
Promoter ID:MM_KWN:23774
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day3,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung
Transcripts:UC008CYI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361749,591,021 - 49,592,002 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1928904 AgrOrtholog
Ensembl Genes ENSMUSG00000064120 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000024797 ENTREZGENE
  ENSMUST00000024797.16 UniProtKB/Swiss-Prot
  ENSMUST00000165390.9 UniProtKB/TrEMBL
  ENSMUST00000173033 ENTREZGENE
  ENSMUST00000173033.8 UniProtKB/Swiss-Prot
  ENSMUST00000173362.8 UniProtKB/TrEMBL
  ENSMUST00000173430.2 UniProtKB/TrEMBL
  ENSMUST00000174647.2 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.70.640 UniProtKB/Swiss-Prot
InterPro Aldolase_TIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Elp3/MiaB/NifB UniProtKB/Swiss-Prot
  Mo_CF_biosynth-C UniProtKB/Swiss-Prot
  MoaA UniProtKB/Swiss-Prot
  MoaA_NifB_PqqE_Fe-S-bd_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MoaC_bact/euk UniProtKB/Swiss-Prot
  MoaC_sf UniProtKB/Swiss-Prot
  Mob_synth_C UniProtKB/Swiss-Prot
  MoCo_biosynth_MoaA/MoaC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Mopterin_CF_biosynth-C_dom UniProtKB/Swiss-Prot
  rSAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:56738 UniProtKB/Swiss-Prot
MGD MGI:1928904 ENTREZGENE
NCBI Gene 56738 ENTREZGENE
PANTHER MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Fer4_12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MoaC UniProtKB/Swiss-Prot
  Mob_synth_C UniProtKB/Swiss-Prot
  Radical_SAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mocs1 PhenoGen
PROSITE MOAA_NIFB_PQQE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RADICAL_SAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Elp3 UniProtKB/Swiss-Prot
Superfamily-SCOP Radical SAM enzymes UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55040 UniProtKB/Swiss-Prot
UniProt B2RVW8 ENTREZGENE
  B7ZWI5 ENTREZGENE
  G3UWH1_MOUSE UniProtKB/TrEMBL
  G3UXJ3_MOUSE UniProtKB/TrEMBL
  G3UXN5_MOUSE UniProtKB/TrEMBL
  G3UYX9_MOUSE UniProtKB/TrEMBL
  MOCS1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q8R058 ENTREZGENE
  Q9CXP1_MOUSE UniProtKB/TrEMBL
  Q9JL31_MOUSE UniProtKB/TrEMBL
  Q9JL32 ENTREZGENE
  Q9JL33 ENTREZGENE
UniProt Secondary B2RVW8 UniProtKB/Swiss-Prot
  B7ZWI5 UniProtKB/Swiss-Prot
  Q8R058 UniProtKB/Swiss-Prot
  Q9JL32 UniProtKB/Swiss-Prot
  Q9JL33 UniProtKB/Swiss-Prot