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Gene: Lars2 (leucyl-tRNA synthetase, mitochondrial) Mus musculus
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Symbol: Lars2
Name: leucyl-tRNA synthetase, mitochondrial
Description: ENCODES a protein that exhibits leucine-tRNA ligase activity (ortholog); INVOLVED IN leucyl-tRNA aminoacylation (ortholog); PARTICIPATES IN valine, leucine and isoleucine biosynthetic pathway; ASSOCIATED WITH HYDROPS, LACTIC ACIDOSIS, AND SIDEROBLASTIC ANEMIA (ortholog); Perrault syndrome (ortholog); Perrault Syndrome 4 (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amiodarone; benzo[a]pyrene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI035546; Kiaa0028; leucine--tRNA ligase; LEURS; probable leucine--tRNA ligase, mitochondrial; probable leucyl-tRNA synthetase, mitochondrial
Orthologs:
Homo sapiens (human) : LARS2 (leucyl-tRNA synthetase 2, mitochondrial)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lars2 (leucyl-tRNA synthetase 2, mitochondrial)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lars2 (leucyl-tRNA synthetase 2, mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : LARS2 (leucyl-tRNA synthetase 2, mitochondrial)
Canis lupus familiaris (dog) : LARS2 (leucyl-tRNA synthetase 2, mitochondrial)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lars2 (leucyl-tRNA synthetase 2, mitochondrial)
Sus scrofa (pig) : LARS2 (leucyl-tRNA synthetase 2, mitochondrial)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm389123,366,927 - 123,462,675 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379123,276,058 - 123,371,782 (+)NCBIGRCm37mm9NCBIm37
MGSCv369123,215,638 - 123,311,362 (+)NCBImm8
Celera9123,819,514 - 123,915,073 (+)NCBICelera
Cytogenetic Map9 F4NCBI
cM Map973.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Lars2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318192
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.