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Gene: Lars2 (leucyl-tRNA synthetase, mitochondrial) Mus musculus
Symbol: Lars2
Name: leucyl-tRNA synthetase, mitochondrial
Description: ENCODES a protein that exhibits leucine-tRNA ligase activity (ortholog); INVOLVED IN leucyl-tRNA aminoacylation (ortholog); PARTICIPATES IN valine, leucine and isoleucine biosynthetic pathway; ASSOCIATED WITH HYDROPS, LACTIC ACIDOSIS, AND SIDEROBLASTIC ANEMIA (ortholog); Perrault syndrome (ortholog); Perrault Syndrome 4 (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amiodarone; benzo[a]pyrene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI035546; Kiaa0028; leucine--tRNA ligase; LEURS; probable leucine--tRNA ligase, mitochondrial; probable leucyl-tRNA synthetase, mitochondrial
Homo sapiens (human) : LARS2 (leucyl-tRNA synthetase 2, mitochondrial)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lars2 (leucyl-tRNA synthetase 2, mitochondrial)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lars2 (leucyl-tRNA synthetase 2, mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : LARS2 (leucyl-tRNA synthetase 2, mitochondrial)
Canis lupus familiaris (dog) : LARS2 (leucyl-tRNA synthetase 2, mitochondrial)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lars2 (leucyl-tRNA synthetase 2, mitochondrial)
Sus scrofa (pig) : LARS2 (leucyl-tRNA synthetase 2, mitochondrial)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm389123,366,927 - 123,462,675 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379123,276,058 - 123,371,782 (+)NCBIGRCm37mm9NCBIm37
MGSCv369123,215,638 - 123,311,362 (+)NCBImm8
Celera9123,819,514 - 123,915,073 (+)NCBICelera
Cytogenetic Map9 F4NCBI
cM Map973.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Lars2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318192
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.