Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of N4BP3 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of N4BP3 mRNA] | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | ISO | N4BP3 (Homo sapiens) | 6480464 | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of N4BP3 mRNA and Estradiol promotes the reaction [N4BP3 protein binds to ESR1 protein] | CTD | PMID:19619570 and PMID:27156127 | 17beta-estradiol | decreases expression | ISO | N4BP3 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of N4BP3 mRNA | CTD | PMID:31614463 | 17beta-estradiol | increases expression | ISO | N4BP3 (Homo sapiens) | 6480464 | Estradiol results in increased expression of N4BP3 mRNA | CTD | PMID:19619570 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | N4BP3 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of N4BP3 mRNA | CTD | PMID:19619570 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | N4bp3 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of N4BP3 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of N4BP3 mRNA | CTD | PMID:24680724 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | N4BP3 (Homo sapiens) | 6480464 | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of N4BP3 mRNA | CTD | PMID:19619570 | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of N4BP3 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | increases expression | ISO | N4bp3 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of N4BP3 mRNA | CTD | PMID:24780913 and PMID:25825206 | aflatoxin B1 | increases expression | ISO | N4bp3 (Rattus norvegicus) | 6480464 | Aflatoxin B1 results in increased expression of N4BP3 mRNA | CTD | PMID:23630614 | aflatoxin B1 | increases methylation | ISO | N4BP3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of N4BP3 intron | CTD | PMID:30157460 | Aflatoxin B2 alpha | decreases methylation | ISO | N4BP3 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of N4BP3 intron | CTD | PMID:30157460 | amiodarone | increases expression | ISO | N4BP3 (Homo sapiens) | 6480464 | Amiodarone results in increased expression of N4BP3 mRNA | CTD | PMID:19774075 | aristolochic acid A | increases expression | ISO | N4BP3 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of N4BP3 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of N4BP3 mRNA | CTD | PMID:21569818 | benzo[a]pyrene | affects methylation | ISO | N4BP3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of N4BP3 promoter | CTD | PMID:27901495 | bisphenol A | affects expression | ISO | N4bp3 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of N4BP3 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of N4BP3 mRNA | CTD | PMID:32156529 | bisphenol A | decreases expression | ISO | N4bp3 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of N4BP3 mRNA | CTD | PMID:34947998 | bisphenol A | increases expression | ISO | N4bp3 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of N4BP3 mRNA | CTD | PMID:30816183 and PMID:32528016 | bisphenol A | increases methylation | ISO | N4bp3 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of N4BP3 gene | CTD | PMID:28505145 | C60 fullerene | decreases expression | ISO | N4bp3 (Rattus norvegicus) | 6480464 | fullerene C60 results in decreased expression of N4BP3 mRNA | CTD | PMID:19167457 | cadmium dichloride | increases methylation | ISO | N4bp3 (Rattus norvegicus) | 6480464 | Cadmium Chloride results in increased methylation of N4BP3 promoter | CTD | PMID:22457795 | calcitriol | increases expression | ISO | N4BP3 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of N4BP3 mRNA | CTD | PMID:26485663 | copper(II) sulfate | increases expression | ISO | N4BP3 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of N4BP3 mRNA | CTD | PMID:19549813 | dextran sulfate | increases expression | EXP | | 6480464 | Dextran Sulfate results in increased expression of N4BP3 mRNA | CTD | PMID:35093514 | dorsomorphin | multiple interactions | ISO | N4BP3 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | N4BP3 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of N4BP3 mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | ISO | N4bp3 (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of N4BP3 mRNA | CTD | PMID:29391264 | entinostat | increases expression | ISO | N4BP3 (Homo sapiens) | 6480464 | entinostat results in increased expression of N4BP3 mRNA | CTD | PMID:26272509 | entinostat | multiple interactions | ISO | N4BP3 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of N4BP3 mRNA | CTD | PMID:27188386 | folic acid | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of N4BP3 mRNA] | CTD | PMID:22206623 | gentamycin | decreases expression | ISO | N4bp3 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of N4BP3 mRNA | CTD | PMID:33387578 | glycidol | increases expression | ISO | N4bp3 (Rattus norvegicus) | 6480464 | glycidol results in increased expression of N4BP3 mRNA | CTD | PMID:24915197 | hydrogen peroxide | affects expression | ISO | N4BP3 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of N4BP3 mRNA | CTD | PMID:20044591 | lead(0) | affects expression | ISO | N4BP3 (Homo sapiens) | 6480464 | Lead affects the expression of N4BP3 mRNA | CTD | PMID:28903495 | menadione | affects expression | ISO | N4BP3 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of N4BP3 mRNA | CTD | PMID:20044591 | N-methyl-4-phenylpyridinium | increases expression | ISO | N4BP3 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of N4BP3 mRNA | CTD | PMID:24810058 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of N4BP3 mRNA | CTD | PMID:34911549 | paracetamol | increases expression | ISO | N4bp3 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of N4BP3 mRNA | CTD | PMID:33387578 | phenobarbital | affects expression | ISO | N4BP3 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of N4BP3 mRNA | CTD | PMID:19159669 | SB 431542 | multiple interactions | ISO | N4BP3 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sotorasib | multiple interactions | ISO | N4BP3 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of N4BP3 mRNA | CTD | PMID:36139627 | sunitinib | decreases expression | ISO | N4BP3 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of N4BP3 mRNA | CTD | PMID:31533062 | thimerosal | decreases expression | ISO | N4BP3 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of N4BP3 mRNA | CTD | PMID:27188386 | thioacetamide | increases expression | ISO | N4bp3 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of N4BP3 mRNA | CTD | PMID:34492290 | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of N4BP3 mRNA | CTD | PMID:23557971 | trametinib | multiple interactions | ISO | N4BP3 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of N4BP3 mRNA | CTD | PMID:36139627 | trichloroethene | increases expression | ISO | N4bp3 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of N4BP3 mRNA | CTD | PMID:33387578 | trichostatin A | decreases expression | ISO | N4BP3 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of N4BP3 mRNA | CTD | PMID:24935251 | triclosan | decreases expression | ISO | N4BP3 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of N4BP3 mRNA | CTD | PMID:30510588 | trovafloxacin | decreases expression | EXP | | 6480464 | trovafloxacin results in decreased expression of N4BP3 mRNA | CTD | PMID:35537566 | valproic acid | decreases expression | ISO | N4BP3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of N4BP3 mRNA | CTD | PMID:26272509 and PMID:28001369 | valproic acid | multiple interactions | ISO | N4BP3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of N4BP3 mRNA | CTD | PMID:27188386 | zearalenone | decreases expression | ISO | N4BP3 (Homo sapiens) | 6480464 | Zearalenone results in decreased expression of N4BP3 mRNA | CTD | PMID:36828454 | |