MRPS5 (mitochondrial ribosomal protein S5) - Rat Genome Database

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Gene: MRPS5 (mitochondrial ribosomal protein S5) Homo sapiens
Analyze
Symbol: MRPS5
Name: mitochondrial ribosomal protein S5
RGD ID: 1318020
HGNC Page HGNC:14498
Description: Enables RNA binding activity. Predicted to be involved in translation. Located in mitochondrion. Part of mitochondrial small ribosomal subunit.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 28S ribosomal protein S5, mitochondrial; mitochondrial 28S ribosomal protein S5; mitochondrial small ribosomal subunit protein uS5m; MRP-S5; S5mt; small ribosomal subunit protein uS5m; uS5m
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: AC079238.1   MRPS5P3   MRPS5P4  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38295,085,369 - 95,122,003 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl295,085,369 - 95,122,006 (-)EnsemblGRCh38hg38GRCh38
GRCh37295,751,114 - 95,787,748 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36295,116,679 - 95,151,481 (-)NCBINCBI36Build 36hg18NCBI36
Build 34295,174,826 - 95,209,628NCBI
Celera290,103,862 - 90,138,778 (-)NCBICelera
Cytogenetic Map2q11.1NCBI
HuRef289,781,783 - 89,816,698 (-)NCBIHuRef
CHM1_1295,757,232 - 95,792,006 (-)NCBICHM1_1
T2T-CHM13v2.0295,591,870 - 95,628,506 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11279123   PMID:11344316   PMID:11402041   PMID:11543634   PMID:12477932   PMID:12706105   PMID:14702039   PMID:15489334   PMID:17353931   PMID:19559069   PMID:20186120   PMID:21081503  
PMID:21145461   PMID:21873635   PMID:22658674   PMID:22681889   PMID:22904065   PMID:22939629   PMID:23443559   PMID:25324306   PMID:25838379   PMID:25921289   PMID:26186194   PMID:26344197  
PMID:26496610   PMID:27023846   PMID:28514442   PMID:28515276   PMID:29229926   PMID:29298432   PMID:29395067   PMID:29568061   PMID:29802200   PMID:29845934   PMID:30033366   PMID:30209976  
PMID:30237157   PMID:30463901   PMID:30471916   PMID:30833792   PMID:31091453   PMID:31239290   PMID:31527615   PMID:31617661   PMID:31822558   PMID:31871319   PMID:31980649   PMID:32129710  
PMID:32353859   PMID:32628020   PMID:32640226   PMID:32707033   PMID:32807901   PMID:32877691   PMID:33060197   PMID:33187986   PMID:33301849   PMID:33306668   PMID:33462405   PMID:33658012  
PMID:33957083   PMID:33961781   PMID:33989516   PMID:34079125   PMID:34373451   PMID:34591612   PMID:34662580   PMID:35013218   PMID:35140242   PMID:35256949   PMID:35384245   PMID:35446349  
PMID:35509820   PMID:35563538   PMID:35850772   PMID:35944360   PMID:36215168   PMID:36424410   PMID:36537216   PMID:36912080   PMID:37827155   PMID:38113892  


Genomics

Comparative Map Data
MRPS5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38295,085,369 - 95,122,003 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl295,085,369 - 95,122,006 (-)EnsemblGRCh38hg38GRCh38
GRCh37295,751,114 - 95,787,748 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36295,116,679 - 95,151,481 (-)NCBINCBI36Build 36hg18NCBI36
Build 34295,174,826 - 95,209,628NCBI
Celera290,103,862 - 90,138,778 (-)NCBICelera
Cytogenetic Map2q11.1NCBI
HuRef289,781,783 - 89,816,698 (-)NCBIHuRef
CHM1_1295,757,232 - 95,792,006 (-)NCBICHM1_1
T2T-CHM13v2.0295,591,870 - 95,628,506 (-)NCBIT2T-CHM13v2.0
Mrps5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392127,429,346 - 127,445,906 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2127,429,142 - 127,448,749 (+)EnsemblGRCm39 Ensembl
GRCm382127,587,426 - 127,603,986 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2127,587,222 - 127,606,829 (+)EnsemblGRCm38mm10GRCm38
MGSCv372127,413,162 - 127,429,722 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362127,278,867 - 127,295,427 (+)NCBIMGSCv36mm8
Celera2128,832,228 - 128,848,847 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map262.05NCBI
Mrps5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83135,274,333 - 135,290,577 (+)NCBIGRCr8
mRatBN7.23114,821,046 - 114,837,291 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3114,821,046 - 114,837,291 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3118,710,122 - 118,726,551 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03127,305,673 - 127,322,102 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03124,966,049 - 124,982,478 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03120,165,953 - 120,182,536 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3120,165,913 - 120,182,536 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03127,150,028 - 127,166,611 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43115,123,330 - 115,139,574 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13115,029,077 - 115,044,508 (+)NCBI
Celera3113,656,776 - 113,673,022 (+)NCBICelera
Cytogenetic Map3q36NCBI
Mrps5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554703,416,731 - 3,443,298 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554703,419,052 - 3,443,481 (-)NCBIChiLan1.0ChiLan1.0
MRPS5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21233,174,259 - 33,209,531 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A33,177,025 - 33,212,290 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A104,285,665 - 104,320,929 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A95,990,642 - 96,025,483 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A95,990,642 - 96,025,483 (-)Ensemblpanpan1.1panPan2
MRPS5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11734,926,674 - 34,952,665 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1734,926,743 - 34,952,473 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1734,695,513 - 34,721,498 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01735,697,965 - 35,723,911 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1735,698,039 - 35,725,575 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11734,826,026 - 34,851,971 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01734,895,002 - 34,920,962 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01735,104,307 - 35,130,278 (+)NCBIUU_Cfam_GSD_1.0
Mrps5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440507347,759 - 64,122 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493718525,998 - 39,685 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MRPS5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl346,137,509 - 46,169,807 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1346,137,566 - 46,169,403 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2348,092,644 - 48,123,464 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MRPS5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114124,884 - 155,600 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041167,509,150 - 167,541,776 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mrps5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247491,901,517 - 1,930,361 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247491,904,450 - 1,930,512 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MRPS5
19 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 2q11.1-12.1(chr2:94817406-103252396)x3 copy number gain See cases [RCV000052946] Chr2:94817406..103252396 [GRCh38]
Chr2:95618109..103868854 [GRCh37]
Chr2:94846878..103235286 [NCBI36]
Chr2:2q11.1-12.1		 pathogenic
GRCh38/hg38 2p11.2-q11.2(chr2:91443218-102334856)x3 copy number gain See cases [RCV000052945] Chr2:91443218..102334856 [GRCh38]
Chr2:91617683..102951316 [GRCh37]
Chr2:90981410..102317748 [NCBI36]
Chr2:2p11.2-q11.2		 pathogenic
GRCh38/hg38 2q11.1(chr2:94751190-95675040)x3 copy number gain See cases [RCV000137332] Chr2:94751190..95675040 [GRCh38]
Chr2:95618109..96340788 [GRCh37]
Chr2:94780662..95704515 [NCBI36]
Chr2:2q11.1		 likely benign
GRCh38/hg38 2q11.1(chr2:95079592-95408265)x3 copy number gain See cases [RCV000141052] Chr2:95079592..95408265 [GRCh38]
Chr2:95745337..96074013 [GRCh37]
Chr2:95109064..95437740 [NCBI36]
Chr2:2q11.1		 uncertain significance
GRCh38/hg38 2q11.1-13(chr2:94678532-110602409)x3 copy number gain See cases [RCV000141075] Chr2:94678532..110602409 [GRCh38]
Chr2:95344257..111359986 [GRCh37]
Chr2:94707984..111076455 [NCBI36]
Chr2:2q11.1-13		 pathogenic
GRCh37/hg19 2q11.1(chr2:95444917-95977790)x3 copy number gain Premature ovarian failure [RCV000225112] Chr2:95444917..95977790 [GRCh37]
Chr2:2q11.1		 uncertain significance
GRCh37/hg19 2p25.3-q37.3(chr2:14238-243048760)x3 copy number gain not provided [RCV000752802] Chr2:14238..243048760 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q11.1-12.3(chr2:95529039-108518266) copy number gain See cases [RCV000449270] Chr2:95529039..108518266 [GRCh37]
Chr2:2q11.1-12.3		 pathogenic
GRCh37/hg19 2q11.1-13(chr2:95327499-111370025)x4 copy number gain See cases [RCV000446842] Chr2:95327499..111370025 [GRCh37]
Chr2:2q11.1-13		 pathogenic
GRCh37/hg19 2q11.1-11.2(chr2:95691600-100587394) copy number gain See cases [RCV000447723] Chr2:95691600..100587394 [GRCh37]
Chr2:2q11.1-11.2		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384) copy number gain See cases [RCV000512056] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q11.1-12.2(chr2:95518497-107186127) copy number gain See cases [RCV000511158] Chr2:95518497..107186127 [GRCh37]
Chr2:2q11.1-12.2		 uncertain significance
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384)x3 copy number gain See cases [RCV000511212] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
Single allele deletion not provided [RCV000714264] Chr2:40608411..146900718 [GRCh37]
Chr2:2p22.1-q22.3		 likely pathogenic
GRCh37/hg19 2q11.1(chr2:95341387-96719347)x1 copy number loss not provided [RCV000682128] Chr2:95341387..96719347 [GRCh37]
Chr2:2q11.1		 uncertain significance
GRCh37/hg19 2p25.3-q37.3(chr2:15672-243101834)x3 copy number gain not provided [RCV000752804] Chr2:15672..243101834 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
NM_031902.5(MRPS5):c.1129T>A (p.Cys377Ser) single nucleotide variant Inborn genetic diseases [RCV003269036] Chr2:95087521 [GRCh38]
Chr2:95753266 [GRCh37]
Chr2:2q11.1		 uncertain significance
GRCh37/hg19 2q11.1(chr2:95476818-96193825)x3 copy number gain not provided [RCV000848612] Chr2:95476818..96193825 [GRCh37]
Chr2:2q11.1		 uncertain significance
GRCh37/hg19 2q11.1-11.2(chr2:95341388-100340514)x3 copy number gain not provided [RCV002473932] Chr2:95341388..100340514 [GRCh37]
Chr2:2q11.1-11.2		 likely pathogenic
NM_031902.5(MRPS5):c.181G>T (p.Ala61Ser) single nucleotide variant Inborn genetic diseases [RCV003198745] Chr2:95115162 [GRCh38]
Chr2:95780907 [GRCh37]
Chr2:2q11.1		 uncertain significance
GRCh37/hg19 2q11.1(chr2:95341387-96735978) copy number loss not specified [RCV002053206] Chr2:95341387..96735978 [GRCh37]
Chr2:2q11.1		 uncertain significance
GRCh37/hg19 2q11.1(chr2:95341686-96193214)x3 copy number gain not provided [RCV001827836] Chr2:95341686..96193214 [GRCh37]
Chr2:2q11.1		 uncertain significance
GRCh37/hg19 2p25.3-q37.3(chr2:1-243199373) copy number gain Mosaic trisomy 2 [RCV002280628] Chr2:1..243199373 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p25.1-q13(chr2:11504318-111365996)x1 copy number loss See cases [RCV002287563] Chr2:11504318..111365996 [GRCh37]
Chr2:2p25.1-q13		 pathogenic
NM_031902.5(MRPS5):c.797A>T (p.Asp266Val) single nucleotide variant Inborn genetic diseases [RCV002902476] Chr2:95101690 [GRCh38]
Chr2:95767435 [GRCh37]
Chr2:2q11.1		 uncertain significance
GRCh37/hg19 2q11.1(chr2:95777121-96248568)x3 copy number gain not provided [RCV002474895] Chr2:95777121..96248568 [GRCh37]
Chr2:2q11.1		 uncertain significance
NM_031902.5(MRPS5):c.559G>T (p.Val187Phe) single nucleotide variant Inborn genetic diseases [RCV002817722] Chr2:95108253 [GRCh38]
Chr2:95773998 [GRCh37]
Chr2:2q11.1		 uncertain significance
NM_031902.5(MRPS5):c.83C>T (p.Ser28Phe) single nucleotide variant Inborn genetic diseases [RCV002689935] Chr2:95117921 [GRCh38]
Chr2:95783666 [GRCh37]
Chr2:2q11.1		 uncertain significance
NM_031902.5(MRPS5):c.194G>A (p.Arg65His) single nucleotide variant Inborn genetic diseases [RCV002778074] Chr2:95115149 [GRCh38]
Chr2:95780894 [GRCh37]
Chr2:2q11.1		 likely benign
NM_031902.5(MRPS5):c.514A>G (p.Met172Val) single nucleotide variant Inborn genetic diseases [RCV002991981] Chr2:95108298 [GRCh38]
Chr2:95774043 [GRCh37]
Chr2:2q11.1		 uncertain significance
NM_031902.5(MRPS5):c.944G>A (p.Arg315His) single nucleotide variant Inborn genetic diseases [RCV002986029] Chr2:95090510 [GRCh38]
Chr2:95756255 [GRCh37]
Chr2:2q11.1		 uncertain significance
NM_031902.5(MRPS5):c.25G>T (p.Gly9Cys) single nucleotide variant Inborn genetic diseases [RCV002931654] Chr2:95121767 [GRCh38]
Chr2:95787512 [GRCh37]
Chr2:2q11.1		 uncertain significance
NM_031902.5(MRPS5):c.202C>G (p.Gln68Glu) single nucleotide variant Inborn genetic diseases [RCV002717984] Chr2:95115141 [GRCh38]
Chr2:95780886 [GRCh37]
Chr2:2q11.1		 uncertain significance
NM_031902.5(MRPS5):c.566G>A (p.Arg189Gln) single nucleotide variant Inborn genetic diseases [RCV003205037] Chr2:95108246 [GRCh38]
Chr2:95773991 [GRCh37]
Chr2:2q11.1		 uncertain significance
NM_031902.5(MRPS5):c.1026G>T (p.Met342Ile) single nucleotide variant Inborn genetic diseases [RCV003175405] Chr2:95090428 [GRCh38]
Chr2:95756173 [GRCh37]
Chr2:2q11.1		 uncertain significance
NM_031902.5(MRPS5):c.1221C>G (p.Asp407Glu) single nucleotide variant Inborn genetic diseases [RCV003212819] Chr2:95087429 [GRCh38]
Chr2:95753174 [GRCh37]
Chr2:2q11.1		 uncertain significance
NM_031902.5(MRPS5):c.533A>G (p.Glu178Gly) single nucleotide variant Inborn genetic diseases [RCV003195704] Chr2:95108279 [GRCh38]
Chr2:95774024 [GRCh37]
Chr2:2q11.1		 uncertain significance
NM_031902.5(MRPS5):c.614C>T (p.Pro205Leu) single nucleotide variant Inborn genetic diseases [RCV003186654] Chr2:95108198 [GRCh38]
Chr2:95773943 [GRCh37]
Chr2:2q11.1		 uncertain significance
NM_031902.5(MRPS5):c.1217T>G (p.Leu406Arg) single nucleotide variant Inborn genetic diseases [RCV003260669] Chr2:95087433 [GRCh38]
Chr2:95753178 [GRCh37]
Chr2:2q11.1		 uncertain significance
NM_031902.5(MRPS5):c.925C>G (p.Pro309Ala) single nucleotide variant Inborn genetic diseases [RCV003362540] Chr2:95100480 [GRCh38]
Chr2:95766225 [GRCh37]
Chr2:2q11.1		 uncertain significance
NM_031902.5(MRPS5):c.791G>A (p.Arg264Gln) single nucleotide variant Inborn genetic diseases [RCV003366080] Chr2:95101696 [GRCh38]
Chr2:95767441 [GRCh37]
Chr2:2q11.1		 uncertain significance
GRCh37/hg19 2q11.1(chr2:95341687-96259199)x3 copy number gain not provided [RCV003484068] Chr2:95341687..96259199 [GRCh37]
Chr2:2q11.1		 uncertain significance
GRCh37/hg19 2q11.1-11.2(chr2:95773428-102550061)x3 copy number gain not provided [RCV003484069] Chr2:95773428..102550061 [GRCh37]
Chr2:2q11.1-11.2		 likely pathogenic
NM_031902.5(MRPS5):c.1119C>A (p.Ile373=) single nucleotide variant not provided [RCV003427109] Chr2:95087531 [GRCh38]
Chr2:95753276 [GRCh37]
Chr2:2q11.1		 likely benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1161
Count of miRNA genes:567
Interacting mature miRNAs:618
Transcripts:ENST00000272418, ENST00000345084, ENST00000461916, ENST00000464458, ENST00000475040, ENST00000475895, ENST00000482568, ENST00000482821
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D2S1681E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37295,753,014 - 95,753,207UniSTSGRCh37
Build 36295,116,741 - 95,116,934RGDNCBI36
Celera290,103,924 - 90,104,117RGD
Cytogenetic Map2p11.2-q11.2UniSTS
HuRef289,781,845 - 89,782,038UniSTS
GeneMap99-GB4 RH Map2335.84UniSTS
RH93830  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37295,770,234 - 95,770,354UniSTSGRCh37
Build 36295,133,961 - 95,134,081RGDNCBI36
Celera290,121,146 - 90,121,266RGD
Cytogenetic Map2p11.2-q11.2UniSTS
HuRef289,799,066 - 89,799,186UniSTS
GeneMap99-GB4 RH Map2336.19UniSTS
RH124030  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37295,765,509 - 95,765,795UniSTSGRCh37
Build 36295,129,236 - 95,129,522RGDNCBI36
Celera290,116,421 - 90,116,707RGD
Cytogenetic Map2p11.2-q11.2UniSTS
HuRef289,794,341 - 89,794,627UniSTS
TNG Radiation Hybrid Map256898.0UniSTS
A003B25  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37295,753,000 - 95,753,169UniSTSGRCh37
Build 36295,116,727 - 95,116,896RGDNCBI36
Celera290,103,910 - 90,104,079RGD
Cytogenetic Map2p11.2-q11.2UniSTS
HuRef289,781,831 - 89,782,000UniSTS
GeneMap99-GB4 RH Map2338.22UniSTS
MRPS5_2701  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37295,752,908 - 95,753,381UniSTSGRCh37
Build 36295,116,635 - 95,117,108RGDNCBI36
Celera290,103,818 - 90,104,291RGD
HuRef289,781,739 - 89,782,212UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2428 2834 1700 601 1854 443 4355 2133 3633 407 1441 1607 171 1204 2788 4
Low 11 157 26 23 97 22 2 64 101 12 19 6 4 1 2 2
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001321995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001321996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001321997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_031902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_136152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_136153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB049940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC092835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK055390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK058160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK124892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK295812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY135346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC000219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC014172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG771419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000272418   ⟹   ENSP00000272418
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl295,085,369 - 95,121,808 (-)Ensembl
RefSeq Acc Id: ENST00000345084   ⟹   ENSP00000341660
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl295,085,391 - 95,122,006 (-)Ensembl
RefSeq Acc Id: ENST00000461916
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl295,085,399 - 95,122,006 (-)Ensembl
RefSeq Acc Id: ENST00000464458
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl295,104,349 - 95,106,688 (-)Ensembl
RefSeq Acc Id: ENST00000475040
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl295,109,990 - 95,159,558 (-)Ensembl
RefSeq Acc Id: ENST00000475895
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl295,085,431 - 95,122,006 (-)Ensembl
RefSeq Acc Id: ENST00000482568
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl295,087,407 - 95,106,653 (-)Ensembl
RefSeq Acc Id: ENST00000482821
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl295,087,208 - 95,093,691 (-)Ensembl
RefSeq Acc Id: ENST00000695432
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl295,085,391 - 95,119,144 (-)Ensembl
RefSeq Acc Id: ENST00000695433   ⟹   ENSP00000511924
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl295,085,391 - 95,120,959 (-)Ensembl
RefSeq Acc Id: ENST00000695434   ⟹   ENSP00000511925
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl295,085,391 - 95,121,557 (-)Ensembl
RefSeq Acc Id: ENST00000695435   ⟹   ENSP00000511926
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl295,085,391 - 95,121,594 (-)Ensembl
RefSeq Acc Id: ENST00000695436   ⟹   ENSP00000511927
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl295,085,391 - 95,121,600 (-)Ensembl
RefSeq Acc Id: ENST00000695437   ⟹   ENSP00000511913
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl295,085,391 - 95,122,006 (-)Ensembl
RefSeq Acc Id: ENST00000695439   ⟹   ENSP00000511914
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl295,085,392 - 95,121,978 (-)Ensembl
RefSeq Acc Id: ENST00000695440
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl295,099,384 - 95,121,833 (-)Ensembl
RefSeq Acc Id: ENST00000695456   ⟹   ENSP00000511928
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl295,085,391 - 95,165,300 (-)Ensembl
RefSeq Acc Id: ENST00000695457   ⟹   ENSP00000511929
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl295,085,431 - 95,165,391 (-)Ensembl
RefSeq Acc Id: NM_001321995   ⟹   NP_001308924
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38295,085,369 - 95,122,003 (-)NCBI
CHM1_1295,755,416 - 95,791,554 (-)NCBI
T2T-CHM13v2.0295,591,870 - 95,628,506 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001321996   ⟹   NP_001308925
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38295,085,369 - 95,121,808 (-)NCBI
CHM1_1295,755,416 - 95,792,024 (-)NCBI
T2T-CHM13v2.0295,591,870 - 95,628,311 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001321997   ⟹   NP_001308926
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38295,085,369 - 95,122,003 (-)NCBI
CHM1_1295,755,416 - 95,791,554 (-)NCBI
T2T-CHM13v2.0295,591,870 - 95,628,506 (-)NCBI
Sequence:
RefSeq Acc Id: NM_031902   ⟹   NP_114108
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38295,085,369 - 95,121,808 (-)NCBI
GRCh37295,752,952 - 95,787,754 (-)RGD
Build 36295,116,679 - 95,151,481 (-)NCBI Archive
Celera290,103,862 - 90,138,778 (-)RGD
HuRef289,781,783 - 89,816,698 (-)ENTREZGENE
CHM1_1295,755,416 - 95,792,024 (-)NCBI
T2T-CHM13v2.0295,591,870 - 95,628,311 (-)NCBI
Sequence:
RefSeq Acc Id: NR_136152
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38295,085,369 - 95,121,808 (-)NCBI
CHM1_1295,755,416 - 95,792,024 (-)NCBI
T2T-CHM13v2.0295,591,870 - 95,628,311 (-)NCBI
Sequence:
RefSeq Acc Id: NR_136153
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38295,085,369 - 95,121,808 (-)NCBI
CHM1_1295,755,416 - 95,792,024 (-)NCBI
T2T-CHM13v2.0295,591,870 - 95,628,311 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_114108   ⟸   NM_031902
- Peptide Label: isoform a
- UniProtKB: Q9BWI4 (UniProtKB/Swiss-Prot),   Q96LJ6 (UniProtKB/Swiss-Prot),   Q4ZFY5 (UniProtKB/Swiss-Prot),   Q9BYC4 (UniProtKB/Swiss-Prot),   P82675 (UniProtKB/Swiss-Prot),   A0A8Q3WKG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001308925   ⟸   NM_001321996
- Peptide Label: isoform c
- Sequence:
RefSeq Acc Id: NP_001308926   ⟸   NM_001321997
- Peptide Label: isoform c
- Sequence:
RefSeq Acc Id: NP_001308924   ⟸   NM_001321995
- Peptide Label: isoform b
- UniProtKB: A0A8Q3SIP9 (UniProtKB/TrEMBL),   A0A8Q3WKG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000341660   ⟸   ENST00000345084
RefSeq Acc Id: ENSP00000272418   ⟸   ENST00000272418
RefSeq Acc Id: ENSP00000511913   ⟸   ENST00000695437
RefSeq Acc Id: ENSP00000511927   ⟸   ENST00000695436
RefSeq Acc Id: ENSP00000511928   ⟸   ENST00000695456
RefSeq Acc Id: ENSP00000511925   ⟸   ENST00000695434
RefSeq Acc Id: ENSP00000511926   ⟸   ENST00000695435
RefSeq Acc Id: ENSP00000511929   ⟸   ENST00000695457
RefSeq Acc Id: ENSP00000511914   ⟸   ENST00000695439
RefSeq Acc Id: ENSP00000511924   ⟸   ENST00000695433
Protein Domains
C2H2-type   S5 DRBM   Small ribosomal subunit protein uS5m N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P82675-F1-model_v2 AlphaFold P82675 1-430 view protein structure

Promoters
RGD ID:6861006
Promoter ID:EPDNEW_H3668
Type:initiation region
Name:MRPS5_1
Description:mitochondrial ribosomal protein S5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H3669  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38295,121,801 - 95,121,861EPDNEW
RGD ID:6861008
Promoter ID:EPDNEW_H3669
Type:initiation region
Name:MRPS5_2
Description:mitochondrial ribosomal protein S5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H3668  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38295,121,981 - 95,122,041EPDNEW
RGD ID:6797832
Promoter ID:HG_KWN:33848
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:NM_031902,   OTTHUMT00000338604,   UC002SUC.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36295,151,126 - 95,151,626 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:14498 AgrOrtholog
COSMIC MRPS5 COSMIC
Ensembl Genes ENSG00000144029 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000289685 Ensembl
Ensembl Transcript ENST00000272418 ENTREZGENE
  ENST00000272418.7 UniProtKB/Swiss-Prot
  ENST00000345084 ENTREZGENE
  ENST00000345084.11 UniProtKB/Swiss-Prot
  ENST00000475040.1 UniProtKB/TrEMBL
  ENST00000695433.1 UniProtKB/TrEMBL
  ENST00000695434 ENTREZGENE
  ENST00000695434.1 UniProtKB/TrEMBL
  ENST00000695435.1 UniProtKB/TrEMBL
  ENST00000695436.1 UniProtKB/TrEMBL
  ENST00000695437 ENTREZGENE
  ENST00000695437.2 UniProtKB/TrEMBL
  ENST00000695439.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.160.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.230.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
GTEx ENSG00000144029 GTEx
  ENSG00000289685 GTEx
HGNC ID HGNC:14498 ENTREZGENE
Human Proteome Map MRPS5 Human Proteome Map
InterPro Ribosomal_S5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S5_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S5_D2-typ_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S5_D2-typ_fold_subgr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S5_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S5_N_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_uS5m_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
KEGG Report hsa:64969 UniProtKB/Swiss-Prot
NCBI Gene 64969 ENTREZGENE
OMIM 611972 OMIM
PANTHER MITOCHONDRIAL RIBOSOMAL PROTEIN S5 UniProtKB/Swiss-Prot
  MITOCHONDRIAL RIBOSOMAL PROTEIN S5 UniProtKB/Swiss-Prot
  MITOCHONDRIAL RIBOSOMAL PROTEIN S5 UniProtKB/TrEMBL
  MITOCHONDRIAL RIBOSOMAL PROTEIN S5 UniProtKB/TrEMBL
  ZINC FINGER AND SCAN DOMAIN-CONTAINING UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 514 UniProtKB/TrEMBL
Pfam Ribosomal_S5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S5_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S5p_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PharmGKB PA31024 PharmGKB
PROSITE RIBOSOMAL_S5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S5_DSRBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP beta-beta-alpha zinc fingers UniProtKB/TrEMBL
  dsRNA-binding domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal protein S5 domain 2-like UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A0A8Q3SHY8_HUMAN UniProtKB/TrEMBL
  A0A8Q3SIP9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8Q3WKG3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8Q3WKH9_HUMAN UniProtKB/TrEMBL
  A0A8Q3WKL2_HUMAN UniProtKB/TrEMBL
  P82675 ENTREZGENE
  Q4ZFY5 ENTREZGENE
  Q96LJ6 ENTREZGENE
  Q9BWI4 ENTREZGENE
  Q9BYC4 ENTREZGENE
  RT05_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary Q4ZFY5 UniProtKB/Swiss-Prot
  Q96LJ6 UniProtKB/Swiss-Prot
  Q9BWI4 UniProtKB/Swiss-Prot
  Q9BYC4 UniProtKB/Swiss-Prot