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Gene: POLM (DNA polymerase mu) Homo sapiens
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Symbol: POLM
Name: DNA polymerase mu
Description: Predicted to have DNA-directed DNA polymerase activity. Predicted to be involved in base-excision repair and double-strand break repair via nonhomologous end joining. Predicted to localize to the nucleus; PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; INTERACTS WITH 17beta-estradiol; 2-methylcholine; 3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DNA-directed DNA/RNA polymerase mu; FLJ35482; Pol iota; Pol Mu; polymerase (DNA directed), mu; polymerase (DNA) mu; polymerase (DNA-directed), mu; Tdt-N; terminal transferase
Orthologs:
Mus musculus (house mouse) : Polm (polymerase (DNA directed), mu)  MGI  Alliance
Rattus norvegicus (Norway rat) : Polm (DNA polymerase mu)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Polm (DNA polymerase mu)
Pan paniscus (bonobo/pygmy chimpanzee) : POLM (DNA polymerase mu)
Canis lupus familiaris (dog) : LOC100685589 (DNA-directed DNA/RNA polymerase mu-like)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Polm (DNA polymerase mu)
Sus scrofa (pig) : POLM (DNA polymerase mu)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl744,072,062 - 44,082,530 (-)Ensembl
GRCh38744,072,062 - 44,082,540 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37744,111,846 - 44,122,129 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36744,078,371 - 44,088,607 (-)NCBINCBI36hg18NCBI36
Build 34743,885,085 - 43,895,322NCBI
Celera744,209,796 - 44,220,079 (-)NCBI
Cytogenetic Map7p13NCBI
HuRef743,997,135 - 44,007,419 (-)NCBIHuRef
CHM1_1744,115,540 - 44,126,017 (-)NCBICHM1_1
CRA_TCAGchr7v2744,151,339 - 44,161,618 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on POLM
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317912
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.