Cd209a (CD209a antigen) - Rat Genome Database
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Gene: Cd209a (CD209a antigen) Mus musculus
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Symbol: Cd209a
Name: CD209a antigen
RGD ID: 1317899
MGI Page MGI
Description: Exhibits carbohydrate derivative binding activity and mannose binding activity. Predicted to be involved in regulation of T cell proliferation. Localizes to cell surface. Human ortholog(s) of this gene implicated in Coronavirus infectious disease; aspergillosis; dengue disease; human immunodeficiency virus infectious disease; and tuberculosis. Orthologous to human CD209 (CD209 molecule); PARTICIPATES IN measles pathway; tuberculosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bis(2-ethylhexyl) phthalate; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD209; CD209 antigen-like protein A; CDSIGN; CI; CIRE; DC-S; DC-SI; DC-SIGN; DC-SIGN1; Dcs; Dcsign; dendritic cell-specific ICAM-3-grabbing non-integrin; MGC130443; SI; SIGN-R1; SIGNR5
RGD Orthologs
Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3983,793,395 - 3,798,984 (-)NCBIGRCm39mm39
GRCm3883,743,395 - 3,748,984 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl83,743,397 - 3,748,984 (-)EnsemblGRCm38mm10GRCm38
MGSCv3783,743,395 - 3,748,984 (-)NCBIGRCm37mm9NCBIm37
MGSCv3683,743,397 - 3,748,930 (-)NCBImm8
Celera83,973,555 - 3,979,144 (-)NCBICelera
Cytogenetic Map8A1.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:7820555   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11581173   PMID:11684292   PMID:12351402   PMID:12456590   PMID:12477932   PMID:15136555   PMID:15588578  
PMID:15795245   PMID:16051608   PMID:16141072   PMID:16141073   PMID:16282604   PMID:16297949   PMID:16569675   PMID:16615889   PMID:16682406   PMID:19770268   PMID:20054124   PMID:20130211  
PMID:20305659   PMID:20558171   PMID:21029863   PMID:21257969   PMID:21427223   PMID:21529282   PMID:21685887   PMID:21860028   PMID:22292921   PMID:22396536   PMID:23019323   PMID:23118208  
PMID:24098455   PMID:25450767   PMID:25574091   PMID:26070485   PMID:26079881   PMID:26106150   PMID:26440060   PMID:27450002   PMID:27596364   PMID:29401627   PMID:29867967   PMID:30335674  
PMID:31358982   PMID:32424104  


Genomics

Comparative Map Data
Cd209a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3983,793,395 - 3,798,984 (-)NCBIGRCm39mm39
GRCm3883,743,395 - 3,748,984 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl83,743,397 - 3,748,984 (-)EnsemblGRCm38mm10GRCm38
MGSCv3783,743,395 - 3,748,984 (-)NCBIGRCm37mm9NCBIm37
MGSCv3683,743,397 - 3,748,930 (-)NCBImm8
Celera83,973,555 - 3,979,144 (-)NCBICelera
Cytogenetic Map8A1.1NCBI
Cd209a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0122,341,960 - 2,347,543 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,341,960 - 2,347,543 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0124,495,061 - 4,500,644 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4122,358,909 - 2,364,492 (+)NCBIRGSC3.4rn4RGSC3.4
Celera123,676,520 - 3,682,107 (-)NCBICelera
Cytogenetic Map12p12NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13432571Scvg1_msubcutaneous vessel growth QTL 1 (mouse)8124701082Mouse
11533914Mts5_mmammary tumor susceptibility 5 (mouse)8130397432Mouse
4140978Nilac5_mnicotine induced locomotor activity 5 (mouse)Not determined8131723288Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:200
Count of miRNA genes:178
Interacting mature miRNAs:184
Transcripts:ENSMUST00000012847
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000012847   ⟹   ENSMUSP00000012847
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl83,743,397 - 3,748,984 (-)Ensembl
RefSeq Acc Id: ENSMUST00000207906
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl83,744,036 - 3,748,930 (-)Ensembl
RefSeq Acc Id: ENSMUST00000207979   ⟹   ENSMUSP00000146702
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl83,743,942 - 3,748,930 (-)Ensembl
RefSeq Acc Id: ENSMUST00000208960   ⟹   ENSMUSP00000146627
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl83,743,801 - 3,748,927 (-)Ensembl
RefSeq Acc Id: NM_133238   ⟹   NP_573501
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3983,793,395 - 3,798,984 (-)NCBI
GRCm3883,743,395 - 3,748,984 (-)ENTREZGENE
MGSCv3783,743,395 - 3,748,984 (-)RGD
Celera83,973,555 - 3,979,144 (-)RGD
cM Map8 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_573501   ⟸   NM_133238
- UniProtKB: Q91ZX1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000012847   ⟸   ENSMUST00000012847
RefSeq Acc Id: ENSMUSP00000146627   ⟸   ENSMUST00000208960
RefSeq Acc Id: ENSMUSP00000146702   ⟸   ENSMUST00000207979
Protein Domains
C-type lectin

Promoters
RGD ID:8666363
Promoter ID:EPDNEW_M11210
Type:multiple initiation site
Name:Cd209a_1
Description:Mus musculus CD209a antigen , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3883,748,927 - 3,748,987EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2157942 AgrOrtholog
Ensembl Genes ENSMUSG00000031494 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000012847 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000146627 UniProtKB/TrEMBL
  ENSMUSP00000146702 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000012847 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000207979 UniProtKB/Swiss-Prot
  ENSMUST00000208960 UniProtKB/TrEMBL
Gene3D-CATH 3.10.100.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro C-type_lectin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C-type_lectin-like/link_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C-type_lectin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CD209-like_CTLD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CTDL_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:170786 UniProtKB/Swiss-Prot
MGD MGI:2157942 ENTREZGENE
NCBI Gene 170786 ENTREZGENE
Pfam Lectin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cd209a PhenoGen
PROSITE C_TYPE_LECTIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C_TYPE_LECTIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CLECT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56436 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A140LI09_MOUSE UniProtKB/TrEMBL
  C209A_MOUSE UniProtKB/Swiss-Prot
  Q2TA59_MOUSE UniProtKB/TrEMBL
  Q91ZX1 ENTREZGENE
UniProt Secondary Q3TAT9 UniProtKB/Swiss-Prot
  Q91ZW5 UniProtKB/Swiss-Prot