Prorsd1 (prolyl-tRNA synthetase domain containing 1) - Rat Genome Database

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Gene: Prorsd1 (prolyl-tRNA synthetase domain containing 1) Mus musculus
Analyze
Symbol: Prorsd1
Name: prolyl-tRNA synthetase domain containing 1
RGD ID: 1317807
MGI Page MGI
Description: Predicted to enable aminoacyl-tRNA editing activity. Is expressed in pancreas primordium dorsal bud. Orthologous to human PRORSD1P (prolyl-tRNA synthetase associated domain containing 1, pseudogene).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2010316F05Rik; MGC143640; Ncrna0; Ncrna00117; prdX deacylase domain-containing protein 1; PrdX-deacylase domain 1; prdX-deacylase domain-containing protein 1; Prdxd; Prdxdd1; prolyl-tRNA synthetase associated domain-containing protein 1; RP23-92B18.3
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391129,461,757 - 29,465,033 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1129,461,757 - 29,465,033 (-)EnsemblGRCm39 Ensembl
GRCm381129,511,757 - 29,515,033 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1129,511,757 - 29,515,033 (-)EnsemblGRCm38mm10GRCm38
MGSCv371129,411,757 - 29,415,033 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361129,413,055 - 29,415,033 (-)NCBIMGSCv36mm8
Celera1131,873,071 - 31,876,339 (-)NCBICelera
Cytogenetic Map11A3.3NCBI
cM Map1116.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:18799693   PMID:21677750   PMID:24390927  


Genomics

Comparative Map Data
Prorsd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391129,461,757 - 29,465,033 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1129,461,757 - 29,465,033 (-)EnsemblGRCm39 Ensembl
GRCm381129,511,757 - 29,515,033 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1129,511,757 - 29,515,033 (-)EnsemblGRCm38mm10GRCm38
MGSCv371129,411,757 - 29,415,033 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361129,413,055 - 29,415,033 (-)NCBIMGSCv36mm8
Celera1131,873,071 - 31,876,339 (-)NCBICelera
Cytogenetic Map11A3.3NCBI
cM Map1116.75NCBI
PRORSD1P
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38255,282,319 - 55,284,472 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl255,282,319 - 55,284,522 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p14 Ensembl255,282,329 - 55,284,437 (+)EnsemblGRCh38hg38GRCh38
GRCh37255,509,455 - 55,511,608 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36255,362,982 - 55,365,112 (+)NCBINCBI36Build 36hg18NCBI36
Celera255,349,956 - 55,352,107 (+)NCBICelera
Cytogenetic Map2p16.1NCBI
HuRef255,244,514 - 55,246,665 (+)NCBIHuRef
CHM1_1255,439,465 - 55,441,616 (+)NCBICHM1_1
T2T-CHM13v2.0255,279,543 - 55,281,678 (+)NCBIT2T-CHM13v2.0
Prorsd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr814107,458,910 - 107,461,179 (-)NCBIGRCr8
mRatBN7.214103,257,979 - 103,260,248 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl14103,257,979 - 103,260,248 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHRSP_BbbUtx_1.014108,831,567 - 108,833,822 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.014105,304,000 - 105,306,255 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014113,938,061 - 113,940,330 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14113,938,061 - 113,940,330 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014113,604,440 - 113,606,709 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414110,530,889 - 110,533,157 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.114110,557,244 - 110,559,466 (-)NCBI
Celera14102,135,084 - 102,137,353 (-)NCBICelera
Cytogenetic Map14q22NCBI
LOC100856725
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11056,164,372 - 56,165,883 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1056,120,464 - 56,122,478 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01057,168,326 - 57,169,840 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11056,869,440 - 56,870,954 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01057,148,673 - 57,150,187 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01057,439,210 - 57,440,715 (+)NCBIUU_Cfam_GSD_1.0
LOC100514282
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1385,945,344 - 85,947,578 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2390,729,092 - 90,731,552 (-)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Prorsd1
72 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:664
Count of miRNA genes:357
Interacting mature miRNAs:409
Transcripts:ENSMUST00000039900, ENSMUST00000133103
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10044008Hbnr15_mHeligmosomoides bakeri nematode resistance 15 (mouse)Not determined1122705234227232Mouse
1300599Cocrb11_mcocaine related behavior 11 (mouse)Not determined11267035536671472Mouse
27095904Scvln12_msacral vertebrae length 2, 10 week (mouse)11325000034495048Mouse
27095909Scvln6_msacral vertebrae length 2, 5 week (mouse)11325000044090827Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
27226741Metcl5_mmetatarsal-calcaneal length 5, 5 week (mouse)11465000046290827Mouse
27226735Metcl16_mmetatarsal-calcaneal length 16, 16 week (mouse)11525000035090827Mouse
1357518Tgyl1_mtriglyceride level 1 (mouse)Not determined11688027733916219Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
1300990Bits3_mbitterness sensitivity 3 (mouse)Not determined11837212142372260Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
1302171Pgia28_mproteoglycan induced arthritis 28 (mouse)Not determined11890609742906218Mouse
4141047Nilac1_mnicotine induced locomotor activity 1 (mouse)Not determined11901178043011942Mouse
13524844Ppiq9_mprepulse inhibition QTL 9 (mouse)11904999735077325Mouse
13463472Mcvq15_mmean corpuscular volume QTL 15 (mouse)111095123244951464Mouse
13463479Mchq19_mmean corpuscular hemoglobin QTL 19 (mouse)111095123244951464Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
10412216Eae44_mexperimental allergic encephalomyelitis susceptibility 44 (mouse)Not determined111226863739950840Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
12801459Leuf1_mleukocyte filtration 1 (mouse)111857861652578716Mouse
12801460Intim2_mintima modifier 2 (mouse)111857861652578716Mouse
12801457Intmrm2_mintima/media ratio modifier 2 (mouse)111857861652578716Mouse
1300938Bulb3_mbulb size 3 (mouse)Not determined111857861652578716Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1300579Thypr1_mthymocyte proliferative response 1 (mouse)Not determined111928257753282715Mouse
14746971Manh70_mmandible shape 70 (mouse)111990589053905890Mouse
4141398Tgq22_mtriglyceride QTL 22 (mouse)Not determined2116340655163406Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1300607Tnbs2_mtri-nitrobenzene sulfonic acid susceptible 2 (mouse)Not determined112489805235126680Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse
1301814Bbaa7_mB.burgdorferi-associated arthritis 7 (mouse)Not determined112601178044264695Mouse
12910801Pwbwq14_mpost-weaning body weight QTL 14 (mouse)112719805750636094Mouse
12910804Pwbwq16_mpost-weaning body weight QTL 16 (mouse)112719805750636094Mouse
12910806Pwbwq15_mpost-weaning body weight QTL 15 (mouse)112719805750636094Mouse
12910817Pwgrq20_mpost-weaning growth rate QTL 20 (mouse)112719805750636094Mouse
12910818Ogrq5_moverall growth rate QTL 5 (mouse)112719805750636094Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000039900   ⟹   ENSMUSP00000048099
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1129,462,876 - 29,465,033 (-)Ensembl
GRCm38.p6 Ensembl1129,512,876 - 29,515,033 (-)Ensembl
RefSeq Acc Id: ENSMUST00000133103   ⟹   ENSMUSP00000117933
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1129,461,757 - 29,465,031 (-)Ensembl
GRCm38.p6 Ensembl1129,511,757 - 29,515,031 (-)Ensembl
RefSeq Acc Id: NM_001163454   ⟹   NP_001156926
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391129,461,757 - 29,465,033 (-)NCBI
GRCm381129,511,757 - 29,515,033 (-)ENTREZGENE
MGSCv371129,411,757 - 29,415,033 (-)RGD
Celera1131,873,071 - 31,876,339 (-)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_026465   ⟹   NP_080741
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391129,461,757 - 29,465,033 (-)NCBI
GRCm381129,511,757 - 29,515,033 (-)ENTREZGENE
MGSCv371129,411,757 - 29,415,033 (-)RGD
Celera1131,873,071 - 31,876,339 (-)RGD
cM Map11 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_080741   ⟸   NM_026465
- Peptide Label: isoform 2
- UniProtKB: Q8BFX7 (UniProtKB/Swiss-Prot),   Q9D820 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001156926   ⟸   NM_001163454
- Peptide Label: isoform 1
- UniProtKB: A0A0A0MQH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000117933   ⟸   ENSMUST00000133103
RefSeq Acc Id: ENSMUSP00000048099   ⟸   ENSMUST00000039900

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D820-F1-model_v2 AlphaFold Q9D820 1-169 view protein structure

Promoters
RGD ID:6821985
Promoter ID:MM_KWN:6787
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000011882,   OTTMUST00000011883,   OTTMUST00000011884
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361129,414,724 - 29,415,224 (+)MPROMDB
RGD ID:8674168
Promoter ID:EPDNEW_M15115
Type:multiple initiation site
Name:Prorsd1_1
Description:Mus musculus prolyl-tRNA synthetase domain containing 1 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381129,515,024 - 29,515,084EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1915189 AgrOrtholog
Ensembl Genes ENSMUSG00000032673 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000039900 ENTREZGENE
  ENSMUST00000039900.4 UniProtKB/Swiss-Prot
  ENSMUST00000133103 ENTREZGENE
  ENSMUST00000133103.2 UniProtKB/TrEMBL
Gene3D-CATH 3.90.960.10 UniProtKB/Swiss-Prot
InterPro ProX/PRXD1 UniProtKB/Swiss-Prot
  YbaK/aa-tRNA-synt-asso_dom_sf UniProtKB/Swiss-Prot
  YbaK/aa-tRNA-synth-assoc-dom UniProtKB/Swiss-Prot
KEGG Report mmu:67939 UniProtKB/Swiss-Prot
MGD MGI:1915189 ENTREZGENE
NCBI Gene 67939 ENTREZGENE
PANTHER PROLYL-TRNA SYNTHETASE ASSOCIATED DOMAIN-CONTAINING PROTEIN 1-RELATED UniProtKB/Swiss-Prot
  PTHR31423 UniProtKB/Swiss-Prot
Pfam tRNA_edit UniProtKB/Swiss-Prot
PhenoGen Prorsd1 PhenoGen
Superfamily-SCOP SSF55826 UniProtKB/Swiss-Prot
UniProt A0A0A0MQH9 ENTREZGENE, UniProtKB/TrEMBL
  PRXD1_MOUSE UniProtKB/Swiss-Prot
  Q8BFX7 ENTREZGENE
  Q9D820 ENTREZGENE
UniProt Secondary Q8BFX7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-27 Prorsd1  prolyl-tRNA synthetase domain containing 1  Prdxdd1  PrdX-deacylase domain 1  Symbol and/or name change 5135510 APPROVED