Ccdc178 (coiled coil domain containing 178) - Rat Genome Database

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Gene: Ccdc178 (coiled coil domain containing 178) Mus musculus
Analyze
Symbol: Ccdc178
Name: coiled coil domain containing 178
RGD ID: 1317774
MGI Page MGI
Description: Predicted to be located in ciliary basal body. Is expressed in testis and thyroid gland. Orthologous to human CCDC178 (coiled-coil domain containing 178).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4921528I01Rik; coiled-coil domain-containing protein 178; hypothetical protein LOC70950; uncharacterized protein C18orf34 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391821,943,954 - 22,304,453 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1821,943,950 - 22,304,499 (-)EnsemblGRCm39 Ensembl
GRCm381821,810,897 - 22,171,396 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1821,810,893 - 22,171,442 (-)EnsemblGRCm38mm10GRCm38
MGSCv371821,969,398 - 22,329,897 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361821,953,907 - 22,314,406 (-)NCBIMGSCv36mm8
Celera1822,312,161 - 22,671,219 (-)NCBICelera
Cytogenetic Map18A2NCBI
cM Map1811.96NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:21677750   PMID:24194600   PMID:27357688  


Genomics

Comparative Map Data
Ccdc178
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391821,943,954 - 22,304,453 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1821,943,950 - 22,304,499 (-)EnsemblGRCm39 Ensembl
GRCm381821,810,897 - 22,171,396 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1821,810,893 - 22,171,442 (-)EnsemblGRCm38mm10GRCm38
MGSCv371821,969,398 - 22,329,897 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361821,953,907 - 22,314,406 (-)NCBIMGSCv36mm8
Celera1822,312,161 - 22,671,219 (-)NCBICelera
Cytogenetic Map18A2NCBI
cM Map1811.96NCBI
CCDC178
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381832,937,406 - 33,441,040 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1832,937,402 - 33,441,101 (-)EnsemblGRCh38hg38GRCh38
GRCh371830,517,370 - 31,021,004 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361828,771,364 - 29,274,683 (-)NCBINCBI36Build 36hg18NCBI36
Build 341828,771,586 - 29,274,683NCBI
Celera1827,325,560 - 27,828,679 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
HuRef1827,375,985 - 27,880,080 (-)NCBIHuRef
CHM1_11830,445,087 - 30,948,305 (-)NCBICHM1_1
T2T-CHM13v2.01833,129,211 - 33,632,807 (-)NCBIT2T-CHM13v2.0
Ccdc178
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81813,349,795 - 13,747,083 (-)NCBIGRCr8
mRatBN7.21813,074,834 - 13,472,732 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1813,075,468 - 13,472,160 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01812,796,155 - 13,199,923 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1812,796,195 - 13,194,952 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01812,788,146 - 12,958,891 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41813,440,195 - 13,817,915 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11813,466,840 - 14,028,711 (-)NCBI
Celera1813,053,917 - 13,450,440 (-)NCBICelera
Cytogenetic Map18p12NCBI
Ccdc178
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540220,076,826 - 20,429,151 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540220,076,834 - 20,429,089 (-)NCBIChiLan1.0ChiLan1.0
CCDC178
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21750,309,597 - 50,813,056 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11836,002,194 - 36,505,653 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01826,140,067 - 26,643,526 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11829,732,628 - 30,235,968 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1829,733,237 - 30,206,721 (-)Ensemblpanpan1.1panPan2
CCDC178
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1756,405,081 - 56,831,787 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl756,404,878 - 56,831,558 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha755,838,729 - 56,264,751 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0756,375,558 - 56,806,303 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl756,375,480 - 56,806,074 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1756,061,670 - 56,491,602 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0756,083,209 - 56,509,498 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0756,379,182 - 56,805,441 (+)NCBIUU_Cfam_GSD_1.0
Ccdc178
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494452,116,768 - 52,457,791 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936682117,455 - 459,368 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCDC178
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6116,764,203 - 117,202,212 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16116,765,040 - 117,187,000 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CCDC178
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11847,296,216 - 47,805,502 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1847,339,825 - 47,637,251 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605021,819,082 - 22,042,170 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccdc178
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247797,726,526 - 7,998,593 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ccdc178
10523 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:227
Count of miRNA genes:171
Interacting mature miRNAs:179
Transcripts:ENSMUST00000025160, ENSMUST00000115837
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142127Rafaril_mRafar interacting locus (mouse)Not determined18123108555Mouse
14928307Manh83_mmandible shape 83 (mouse)18126902168Mouse
11354953Mom21_mmodifier of Min 21 (mouse)18128893823Mouse
12801462Intim3_mintima modifier 3 (mouse)18131720756Mouse
12801458Intmrm3_mintima/media ratio modifier 3 (mouse)18131720756Mouse
13207585Mwmlpt3_mMorris water maze latency to platform, training, 3 (mouse)18133547739Mouse
13207589Mwmlpa3_mMorris water maze latency to platform, all, 3 (mouse)18133547739Mouse
27226723Tibw9_mtibia width 9, proximal, 16 week (mouse)18320000060933072Mouse
1558849W3q15_mweight 3 weeks QTL 15 (mouse)Not determined18504111961272643Mouse
1558873Hrtfm7_mheart failure modifier 7 (mouse)Not determined18808696442087106Mouse
13504732Cath6_mcarotid atherosclerosis 6 (mouse)181363712647637126Mouse
1357603Mom3_mmodifier of Min 3 (mouse)Not determined181403002367098962Mouse
1300994Pvcan3_mprotection against vaginal candidiasis 3 (mouse)Not determined181619964050199776Mouse
1301307Phospq1_mphospholipid QTL 1 (mouse)Not determined181813970452139859Mouse
12910787Pwbwq18_mpost-weaning body weight QTL 18 (mouse)181826552930570819Mouse
12910805Pwbwq17_mpost-weaning body weight QTL 17 (mouse)181826552930570819Mouse
12910819Ogrq6_moverall growth rate QTL 6 (mouse)181826552930570819Mouse
1300638Im7_mimmunoregulatory 7 (mouse)Not determined181901887453018992Mouse
1558743Kcal1_mkilocalorie 1 (mouse)Not determined181901887453018992Mouse
11532709Sluc41_msusceptibility to lung cancer 41 (mouse)182095369457590708Mouse
13463476Hctq8_mhematocrit QTL 8 (mouse)182121758055217727Mouse
1301950Otx2m1_morthodenticle homolog 2 (Drosophila) modifier 1 (mouse)Not determined182156868236187740Mouse

Markers in Region
UniSTS:224646  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381821,856,213 - 21,856,376UniSTSGRCm38
MGSCv371822,014,714 - 22,014,877UniSTSGRCm37
Celera1822,357,809 - 22,357,972UniSTS
Cytogenetic Map18A2UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000025160   ⟹   ENSMUSP00000025160
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1821,943,954 - 22,304,453 (-)Ensembl
GRCm38.p6 Ensembl1821,810,897 - 22,171,396 (-)Ensembl
RefSeq Acc Id: ENSMUST00000115837   ⟹   ENSMUSP00000111503
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1821,944,355 - 22,299,533 (-)Ensembl
GRCm38.p6 Ensembl1821,811,298 - 22,166,476 (-)Ensembl
RefSeq Acc Id: ENSMUST00000234661   ⟹   ENSMUSP00000157287
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1822,279,987 - 22,304,435 (-)Ensembl
GRCm38.p6 Ensembl1822,146,930 - 22,171,378 (-)Ensembl
RefSeq Acc Id: ENSMUST00000234736   ⟹   ENSMUSP00000157323
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1821,943,950 - 22,304,499 (-)Ensembl
GRCm38.p6 Ensembl1821,810,893 - 22,171,442 (-)Ensembl
RefSeq Acc Id: NM_027616   ⟹   NP_081892
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391821,943,954 - 22,304,453 (-)NCBI
GRCm381821,810,897 - 22,171,396 (-)NCBI
MGSCv371821,969,398 - 22,329,897 (-)RGD
Celera1822,312,161 - 22,671,219 (-)RGD
cM Map18 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_081892   ⟸   NM_027616
- UniProtKB: B7ZN78 (UniProtKB/Swiss-Prot),   Q8CDV0 (UniProtKB/Swiss-Prot),   B7ZN80 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000111503   ⟸   ENSMUST00000115837
RefSeq Acc Id: ENSMUSP00000025160   ⟸   ENSMUST00000025160
RefSeq Acc Id: ENSMUSP00000157323   ⟸   ENSMUST00000234736
RefSeq Acc Id: ENSMUSP00000157287   ⟸   ENSMUST00000234661

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8CDV0-F1-model_v2 AlphaFold Q8CDV0 1-866 view protein structure

Promoters
RGD ID:13677224
Promoter ID:EPDNEW_M22761
Type:multiple initiation site
Name:Ccdc178_1
Description:Mus musculus coiled coil domain containing 178 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381822,171,396 - 22,171,456EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1918200 AgrOrtholog
Ensembl Genes ENSMUSG00000024306 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000025160 ENTREZGENE
  ENSMUST00000025160.9 UniProtKB/Swiss-Prot
  ENSMUST00000115837.3 UniProtKB/Swiss-Prot
  ENSMUST00000234661.2 UniProtKB/TrEMBL
  ENSMUST00000234736.2 UniProtKB/Swiss-Prot
InterPro CCDC178 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:70950 UniProtKB/Swiss-Prot
MGD MGI:1918200 ENTREZGENE
NCBI Gene 70950 ENTREZGENE
PANTHER COILED-COIL DOMAIN-CONTAINING PROTEIN 178 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR35088 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ccdc178 PhenoGen
UniProt A0A3Q4EC56_MOUSE UniProtKB/TrEMBL
  B7ZN78 ENTREZGENE
  B7ZN80 ENTREZGENE, UniProtKB/TrEMBL
  CC178_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q9CUR1_MOUSE UniProtKB/TrEMBL
UniProt Secondary B7ZN78 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-11-27 Ccdc178  coiled coil domain containing 178  4921528I01Rik  RIKEN cDNA 4921528I01 gene  Symbol and/or name change 5135510 APPROVED