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Gene: PWP2 (PWP2 small subunit processome component) Homo sapiens
Symbol: PWP2
Name: PWP2 small subunit processome component
Description: Exhibits RNA binding activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and ribosomal small subunit assembly. Predicted to localize to Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome; PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH 17beta-estradiol; antirheumatic drug; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: EHOC-17; periodic tryptophan protein 2 homolog; PWP2 periodic tryptophan protein homolog; PWP2 periodic tryptophan protein homolog (yeast); PWP2, small subunit processome component; PWP2, UTPB SSU processome subunit; PWP2H; UTP1
Mus musculus (house mouse) : Pwp2 (PWP2 periodic tryptophan protein homolog (yeast))  MGI  Alliance
Rattus norvegicus (Norway rat) : Pwp2 (PWP2, small subunit processome component)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pwp2 (PWP2 small subunit processome component)
Pan paniscus (bonobo/pygmy chimpanzee) : PWP2 (PWP2 small subunit processome component)
Canis lupus familiaris (dog) : PWP2 (PWP2 small subunit processome component)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pwp2 (PWP2 small subunit processome component)
Sus scrofa (pig) : PWP2 (PWP2 small subunit processome component)
Chlorocebus sabaeus (African green monkey) : PWP2 (PWP2 small subunit processome component)
Heterocephalus glaber (naked mole-rat) : Pwp2 (PWP2 small subunit processome component)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2144,107,373 - 44,131,181 (+)EnsemblGRCh38hg38GRCh38
GRCh382144,107,323 - 44,131,181 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372145,527,208 - 45,551,063 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362144,351,636 - 44,375,491 (+)NCBINCBI36hg18NCBI36
Build 342144,351,635 - 44,375,490NCBI
Celera2130,632,847 - 30,656,721 (+)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2130,897,487 - 30,921,342 (+)NCBIHuRef
CHM1_12145,088,074 - 45,111,933 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PWP2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317740
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.