Mgat4e (MGAT4 family, member E) - Rat Genome Database

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Gene: Mgat4e (MGAT4 family, member E) Mus musculus
Analyze
Symbol: Mgat4e
Name: MGAT4 family, member E
RGD ID: 1317697
MGI Page MGI
Description: Predicted to enable acetylglucosaminyltransferase activity. Predicted to be involved in protein N-linked glycosylation. Orthologous to human MGAT4EP (MGAT4 family member E, pseudogene).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4931440L10Rik; alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like; alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein LOC641515 homolog; alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4E; RIKEN cDNA 4931440L10
RGD Orthologs
Human
Rat
Dog
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391134,468,679 - 134,489,484 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1134,468,679 - 134,477,420 (-)EnsemblGRCm39 Ensembl
GRCm381134,540,941 - 134,561,746 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1134,540,941 - 134,549,682 (-)EnsemblGRCm38mm10GRCm38
MGSCv371136,437,522 - 136,443,599 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361136,357,357 - 136,366,093 (-)NCBIMGSCv36mm8
Celera1137,148,098 - 137,154,113 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map158.24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:18799693   PMID:21873635  


Genomics

Comparative Map Data
Mgat4e
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391134,468,679 - 134,489,484 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1134,468,679 - 134,477,420 (-)EnsemblGRCm39 Ensembl
GRCm381134,540,941 - 134,561,746 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1134,540,941 - 134,549,682 (-)EnsemblGRCm38mm10GRCm38
MGSCv371136,437,522 - 136,443,599 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361136,357,357 - 136,366,093 (-)NCBIMGSCv36mm8
Celera1137,148,098 - 137,154,113 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map158.24NCBI
MGAT4EP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381202,820,257 - 202,827,225 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1202,825,186 - 202,826,320 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p14 Ensembl1202,820,266 - 202,827,225 (+)EnsemblGRCh38hg38GRCh38
GRCh371202,789,385 - 202,796,353 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361201,059,032 - 201,062,062 (+)NCBINCBI36Build 36hg18NCBI36
Celera1175,918,607 - 175,925,575 (+)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1173,959,923 - 173,961,015 (+)NCBIHuRef
CHM1_11204,216,567 - 204,217,659 (+)NCBICHM1_1
T2T-CHM13v2.01202,082,918 - 202,089,886 (+)NCBIT2T-CHM13v2.0
Mgat4e
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81348,534,792 - 48,555,956 (-)NCBIGRCr8
mRatBN7.21345,982,979 - 45,991,793 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1345,982,164 - 46,001,050 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01351,364,803 - 51,382,702 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1351,364,014 - 51,373,399 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01356,419,465 - 56,428,440 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41347,483,065 - 47,491,657 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1346,309,194 - 46,327,094 (-)NCBICelera
Cytogenetic Map13q13NCBI
LOC102151492
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.17321,551 - 327,610 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha7375,859 - 381,918 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.07330,683 - 336,742 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.17319,515 - 325,573 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.07428,336 - 434,395 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.07451,595 - 457,654 (-)NCBIUU_Cfam_GSD_1.0

Variants

.
Variants in Mgat4e
721 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:207
Count of miRNA genes:99
Interacting mature miRNAs:105
Transcripts:ENSMUST00000052911, ENSMUST00000172898
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134760138150193871Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134760138150193871Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134760138150193871Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163920002153557562Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173755175147125370Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74516235148715579Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)175976637148775742Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)175976637181327565Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782291982147125370Mouse
1357439Popoa_mpremature ovulation and primary oocyte arrest (mouse)Not determined182643189135615379Mouse
27095913Scvln2_msacral vertebrae length 2, 5 week (mouse)194127725148775742Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194127725172027567Mouse
27226779Tibl1_mtibia length 1, 5 week (mouse)195527725162027569Mouse
1301193Lxw3_mlupus BXSB x NZW 3 (mouse)Not determined1102968534136968667Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1103933405191225397Mouse
12790994Aaaq1_maortic arch angle QTL 1 (mouse)1109495943143495943Mouse
1301979Melm1_mmelanoma modifier 1 (mouse)Not determined1109638262143638479Mouse
1357600Obq17_mobesity QTL 17 (mouse)Not determined1110553179144553298Mouse
10401248Bglu12_mblood glucose level 12 (mouse)Not determined1110553179144553298Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112008822168186402Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112008822175468938Mouse
1301249Sbw1_msplenomegaly-NZB x NZW 1 (mouse)Not determined1112131005146131085Mouse
10045640Jckm4_mjuvenile cystic kidney modifier 4 (mouse)Not determined1116290836150290937Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117527730179827565Mouse
1302161Exq2_mexploratory and excitability QTL 2 (mouse)Not determined1118099720152099816Mouse
27226714Metcl1_mmetatarsal-calcaneal length 1, 5 week (mouse)1121727729139727738Mouse
27226740Metcl13_mmetatarsal-calcaneal length 13, 16 week (mouse)1121727729153775746Mouse
27226743Metcl7_mmetatarsal-calcaneal length 7, 10 week (mouse)1121727729153875746Mouse
27226767Tibl10_mtibia length 10, 10 week (mouse)1121727729164827569Mouse
27226799Feml5_mfemur length 5, 5 week (mouse)1122027729164827569Mouse
12880408V125Dq3_mvitamin D active form serum level QTL 3 (mouse)1122927738156927738Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128727737181327565Mouse
1301608Emo3_memotionality 3 (mouse)Not determined1129130858163130993Mouse
1302128Ity3_mimmunity to S. typhimurium 3 (mouse)Not determined11131156308165139464Mouse
13524520Bodwtq1_mbody wweight QTL 1 (mouse)1131191160135621161Mouse
13513913Heal51_mwound healing/ regeneration 51 (mouse)1131780648135499606Mouse
14746980Manh50_mmandible shape 50 (mouse)1134131564168131564Mouse
13504831Bacszq1_mbaculum size QTL 1 (mouse)1134331161148128608Mouse


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000052911   ⟹   ENSMUSP00000125929
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1134,468,683 - 134,474,760 (-)Ensembl
GRCm38.p6 Ensembl1134,540,945 - 134,547,022 (-)Ensembl
RefSeq Acc Id: ENSMUST00000172898   ⟹   ENSMUSP00000133717
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1134,468,679 - 134,477,420 (-)Ensembl
GRCm38.p6 Ensembl1134,540,941 - 134,549,682 (-)Ensembl
RefSeq Acc Id: ENSMUST00000185836   ⟹   ENSMUSP00000139781
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1134,468,693 - 134,474,688 (-)Ensembl
GRCm38.p6 Ensembl1134,540,955 - 134,546,950 (-)Ensembl
RefSeq Acc Id: NM_001145300   ⟹   NP_001138772
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391134,468,679 - 134,477,420 (-)NCBI
GRCm381134,540,941 - 134,549,682 (-)NCBI
MGSCv371136,437,522 - 136,443,599 (-)RGD
Celera1137,148,094 - 137,156,787 (-)NCBI
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001291015   ⟹   NP_001277944
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391134,468,679 - 134,477,420 (-)NCBI
GRCm381134,540,941 - 134,549,682 (-)NCBI
Celera1137,148,094 - 137,156,787 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011248086   ⟹   XP_011246388
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391134,468,679 - 134,489,484 (-)NCBI
GRCm381134,540,941 - 134,561,746 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001138772   ⟸   NM_001145300
- Peptide Label: isoform 1
- UniProtKB: E9Q5L0 (UniProtKB/Swiss-Prot),   B7ZNB9 (UniProtKB/Swiss-Prot),   Q8C1J0 (UniProtKB/Swiss-Prot),   A6H684 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001277944   ⟸   NM_001291015
- Peptide Label: isoform 2
- UniProtKB: A6H684 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011246388   ⟸   XM_011248086
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000125929   ⟸   ENSMUST00000052911
RefSeq Acc Id: ENSMUSP00000133717   ⟸   ENSMUST00000172898
RefSeq Acc Id: ENSMUSP00000139781   ⟸   ENSMUST00000185836

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A6H684-F1-model_v2 AlphaFold A6H684 1-439 view protein structure

Promoters
RGD ID:6875022
Promoter ID:EPDNEW_M962
Type:initiation region
Name:Mgat4e_1
Description:Mus musculus MGAT4 family, member E , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381134,549,668 - 134,549,728EPDNEW
RGD ID:6848547
Promoter ID:MM_TRO:486
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:MTR047620.1.2021.0,   MTR047620.1.2021.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361136,452,951 - 136,453,827 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1918251 AgrOrtholog
Ensembl Genes ENSMUSG00000046367 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000052911.8 UniProtKB/Swiss-Prot
  ENSMUST00000172898 ENTREZGENE
  ENSMUST00000172898.2 UniProtKB/Swiss-Prot
  ENSMUST00000185836.2 UniProtKB/TrEMBL
InterPro Glyco_transf_54 UniProtKB/Swiss-Prot
KEGG Report mmu:71001 UniProtKB/Swiss-Prot
MGD MGI:1918251 ENTREZGENE
NCBI Gene 71001 ENTREZGENE
PANTHER ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE-LIKE PROTEIN MGAT4E UniProtKB/Swiss-Prot
  PTHR12062 UniProtKB/Swiss-Prot
Pfam Glyco_transf_54 UniProtKB/Swiss-Prot
PhenoGen Mgat4e PhenoGen
UniProt A0A087WPH6_MOUSE UniProtKB/TrEMBL
  A6H684 ENTREZGENE
  B7ZNB9 ENTREZGENE
  E9Q5L0 ENTREZGENE
  MGT4E_MOUSE UniProtKB/Swiss-Prot
  Q8C1J0 ENTREZGENE
UniProt Secondary B7ZNB9 UniProtKB/Swiss-Prot
  E9Q5L0 UniProtKB/Swiss-Prot
  Q8C1J0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-08-05 Mgat4e  MGAT4 family, member E  4931440L10Rik  RIKEN cDNA 4931440L10 gene  Symbol and/or name change 5135510 APPROVED