Mpv17l2 (MPV17 mitochondrial membrane protein-like 2) - Rat Genome Database
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Gene: Mpv17l2 (MPV17 mitochondrial membrane protein-like 2) Mus musculus
Analyze
Symbol: Mpv17l2
Name: MPV17 mitochondrial membrane protein-like 2
RGD ID: 1317620
MGI Page MGI
Description: Predicted to be involved in mitochondrial ribosome assembly and positive regulation of mitochondrial translation. Localizes to mitochondrion. Orthologous to human MPV17L2 (MPV17 mitochondrial inner membrane protein like 2); INTERACTS WITH 1,2-dimethylhydrazine; benzo[a]pyrene; carbon nanotube.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Fksg2; Fksg24; MGC63135; mpv17-like protein 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39871,211,295 - 71,213,589 (-)NCBIGRCm39mm39
GRCm38870,758,649 - 70,760,932 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,758,649 - 70,760,946 (-)EnsemblGRCm38mm10GRCm38
MGSCv37873,282,548 - 73,284,820 (-)NCBIGRCm37mm9NCBIm37
MGSCv36873,687,638 - 73,689,910 (-)NCBImm8
Celera873,319,947 - 73,322,220 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:15782199   PMID:16141072   PMID:16141073   PMID:18614015   PMID:21267068   PMID:21873635  


Genomics

Comparative Map Data
Mpv17l2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39871,211,295 - 71,213,589 (-)NCBIGRCm39mm39
GRCm38870,758,649 - 70,760,932 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,758,649 - 70,760,946 (-)EnsemblGRCm38mm10GRCm38
MGSCv37873,282,548 - 73,284,820 (-)NCBIGRCm37mm9NCBIm37
MGSCv36873,687,638 - 73,689,910 (-)NCBImm8
Celera873,319,947 - 73,322,220 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
MPV17L2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1918,193,218 - 18,196,948 (+)EnsemblGRCh38hg38GRCh38
GRCh381918,193,218 - 18,196,948 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371918,303,986 - 18,307,552 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361918,165,040 - 18,168,552 (+)NCBINCBI36hg18NCBI36
Celera1918,205,777 - 18,209,289 (+)NCBI
Cytogenetic Map19p13.11NCBI
HuRef1917,867,488 - 17,871,000 (+)NCBIHuRef
CHM1_11918,303,580 - 18,307,092 (+)NCBICHM1_1
Mpv17l2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01620,432,734 - 20,435,125 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,432,899 - 20,435,974 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,289,807 - 20,292,193 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,187,406 - 19,189,792 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11619,187,448 - 19,189,790 (+)NCBI
Celera1618,874,042 - 18,876,428 (+)NCBICelera
Cytogenetic Map16p14NCBI
Mpv17l2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555243,224,992 - 3,226,373 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555243,224,356 - 3,226,373 (-)NCBIChiLan1.0ChiLan1.0
MPV17L2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11918,645,830 - 18,649,109 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1918,645,830 - 18,649,085 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01917,669,334 - 17,672,802 (+)NCBIMhudiblu_PPA_v0panPan3
MPV17L2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2044,799,457 - 44,805,239 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12044,799,730 - 44,805,876 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Mpv17l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365962,996,049 - 2,999,334 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MPV17L2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl259,609,818 - 59,613,161 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1259,609,816 - 59,613,162 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2259,149,124 - 59,152,439 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MPV17L2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl616,668,141 - 16,670,676 (+)Ensembl
ChlSab1.1616,667,878 - 16,671,368 (+)NCBI
Mpv17l2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249081,530,670 - 1,532,821 (+)NCBI

Position Markers
RH133798  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38870,758,452 - 70,758,608UniSTSGRCm38
MGSCv37873,282,351 - 73,282,507UniSTSGRCm37
Celera873,319,750 - 73,319,906UniSTS
Cytogenetic Map8B3.3UniSTS
X72966  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38870,758,837 - 70,758,949UniSTSGRCm38
MGSCv37873,282,736 - 73,282,848UniSTSGRCm37
Celera873,320,135 - 73,320,247UniSTS
Cytogenetic Map8B3.3UniSTS
Whitehead/MRC_RH8744.22UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81472316071045600Mouse
1357811Orq3_movulation rate QTL 3 (mouse)Not determined83201654471287993Mouse
4141437W10q14_mweight 10 weeks QTL 14 (mouse)Not determined3201654471287993Mouse
4141172W6q9_mweight 6 weeks QTL 9 (mouse)Not determined3201654471287993Mouse
4140966Egq12_mearly growth QTL 12 (mouse)Not determined3201654471287993Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84429488078295025Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84763703081637146Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84763703081637146Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84773713481737254Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84879293982793021Mouse
14746987Manh64_mmandible shape 64 (mouse)85005330684053306Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85005330684053306Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined86535776899357920Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined86560020799600347Mouse
10766466Char12_mP. chabaudi malaria resistance QTL 12 (mouse)86826982782600347Mouse
1301767Fcsa2_mfemoral cross-sectional area 2 (mouse)Not determined870305375104305495Mouse
4142283Imraq2_mimmune response to AAV2 QTL 2 (mouse)Not determined870305375104305495Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:188
Count of miRNA genes:169
Interacting mature miRNAs:177
Transcripts:ENSMUST00000038626
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000038626   ⟹   ENSMUSP00000037929
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl870,758,649 - 70,760,946 (-)Ensembl
RefSeq Acc Id: ENSMUST00000212385
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl870,760,377 - 70,760,900 (-)Ensembl
RefSeq Acc Id: ENSMUST00000212617   ⟹   ENSMUSP00000148307
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl870,759,416 - 70,760,462 (-)Ensembl
RefSeq Acc Id: ENSMUST00000213010
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl870,759,009 - 70,760,837 (-)Ensembl
RefSeq Acc Id: NM_183170   ⟹   NP_898993
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39871,211,295 - 71,213,567 (-)NCBI
GRCm38870,758,649 - 70,760,921 (-)ENTREZGENE
MGSCv37873,282,548 - 73,284,820 (-)RGD
Celera873,319,947 - 73,322,220 (-)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011242299   ⟹   XP_011240601
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39871,211,295 - 71,213,589 (-)NCBI
GRCm38870,758,649 - 70,760,932 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_898993   ⟸   NM_183170
- UniProtKB: Q8VIK2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011240601   ⟸   XM_011242299
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000148307   ⟸   ENSMUST00000212617
RefSeq Acc Id: ENSMUSP00000037929   ⟸   ENSMUST00000038626

Promoters
RGD ID:8667343
Promoter ID:EPDNEW_M11703
Type:initiation region
Name:Mpv17l2_1
Description:Mus musculus MPV17 mitochondrial membrane protein-like 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38870,760,935 - 70,760,995EPDNEW
RGD ID:6843487
Promoter ID:MM_KWN:54738
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000038626
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36873,284,681 - 73,285,687 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2681846 AgrOrtholog
Ensembl Genes ENSMUSG00000035559 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSMUSG00000111476 UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000037929 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000148307 UniProtKB/TrEMBL
  ENSMUSP00000149211 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000038626 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000212617 UniProtKB/TrEMBL
  ENSMUST00000216536 UniProtKB/Swiss-Prot
InterPro Mpv17_PMP22 UniProtKB/Swiss-Prot
KEGG Report mmu:234384 UniProtKB/Swiss-Prot
MGD MGI:2681846 ENTREZGENE
NCBI Gene 234384 ENTREZGENE
PANTHER PTHR11266 UniProtKB/Swiss-Prot
Pfam Mpv17_PMP22 UniProtKB/Swiss-Prot
PhenoGen Mpv17l2 PhenoGen
UniGene Mm.213010 ENTREZGENE
UniProt A0A1D5RLC2_MOUSE UniProtKB/TrEMBL
  M17L2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q3THH2 UniProtKB/Swiss-Prot
  Q80UR1 UniProtKB/Swiss-Prot