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Gene: Vps11 (VPS11, CORVET/HOPS core subunit) Mus musculus
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Symbol: Vps11
Name: VPS11, CORVET/HOPS core subunit
Description: Predicted to have protein binding activity, bridging; protein domain specific binding activity; and syntaxin binding activity. Involved in toxin transport. Localizes to the actin filament; endosome; and presynaptic active zone. Colocalizes with the AP-3 adaptor complex. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 12. Orthologous to human VPS11 (VPS11 core subunit of CORVET and HOPS complexes); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; clofibrate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1200011A11Rik; vacuolar protein sorting 11; vacuolar protein sorting 11 (yeast); vacuolar protein sorting-associated protein 11 homolog
Orthologs:
Homo sapiens (human) : VPS11 (VPS11 core subunit of CORVET and HOPS complexes)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Vps11 (VPS11 core subunit of CORVET and HOPS complexes)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vps11 (VPS11 core subunit of CORVET and HOPS complexes)
Pan paniscus (bonobo/pygmy chimpanzee) : VPS11 (VPS11 core subunit of CORVET and HOPS complexes)
Canis lupus familiaris (dog) : VPS11 (VPS11 core subunit of CORVET and HOPS complexes)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vps11 (VPS11 core subunit of CORVET and HOPS complexes)
Sus scrofa (pig) : VPS11 (VPS11 core subunit of CORVET and HOPS complexes)
Chlorocebus sabaeus (African green monkey) : VPS11 (VPS11 core subunit of CORVET and HOPS complexes)
Heterocephalus glaber (naked mole-rat) : Vps11 (VPS11 core subunit of CORVET and HOPS complexes)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl944,347,749 - 44,361,670 (-)Ensembl
GRCm38944,347,749 - 44,361,673 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37944,156,188 - 44,169,753 (-)NCBIGRCm37mm9NCBIm37
MGSCv36944,099,100 - 44,112,665 (-)NCBImm8
Celera941,603,071 - 41,616,610 (-)NCBICelera
Cytogenetic Map9 A5.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Vps11
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317576
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.