Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of CPNE5 mRNA | CTD | PMID:36331819 | 1,2-dichloroethane | decreases expression | EXP | | 6480464 | ethylene dichloride results in decreased expression of CPNE5 mRNA | CTD | PMID:28189721 | 1,2-dichloroethane | affects expression | EXP | | 6480464 | ethylene dichloride affects the expression of CPNE5 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of CPNE5 mRNA | CTD | PMID:22206623 | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Cpne5 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CPNE5 mRNA | CTD | PMID:32109520 and PMID:33387578 | 4,4'-sulfonyldiphenol | decreases expression | EXP | | 6480464 | bisphenol S results in decreased expression of CPNE5 mRNA | CTD | PMID:30951980 | 4,4'-sulfonyldiphenol | affects methylation | EXP | | 6480464 | bisphenol S affects the methylation of CPNE5 exon | CTD | PMID:33297965 | Aflatoxin B2 alpha | decreases methylation | ISO | CPNE5 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of CPNE5 exon and aflatoxin B2 results in decreased methylation of CPNE5 intron | CTD | PMID:30157460 | benzo[a]pyrene | decreases expression | ISO | Cpne5 (Rattus norvegicus) | 6480464 | Benzo(a)pyrene results in decreased expression of CPNE5 mRNA | CTD | PMID:21839799 | benzo[a]pyrene | increases methylation | ISO | CPNE5 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of CPNE5 promoter | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | CPNE5 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of CPNE5 exon and Benzo(a)pyrene affects the methylation of CPNE5 intron | CTD | PMID:30157460 | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of CPNE5 mRNA | CTD | PMID:27858113 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of CPNE5 mRNA | CTD | PMID:22610609 | benzo[b]fluoranthene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of CPNE5 mRNA | CTD | PMID:27858113 | benzo[e]pyrene | decreases methylation | ISO | CPNE5 (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of CPNE5 exon and benzo(e)pyrene results in decreased methylation of CPNE5 intron | CTD | PMID:30157460 | Benzo[ghi]perylene | decreases expression | EXP | | 6480464 | 1 and 12-benzoperylene results in decreased expression of CPNE5 mRNA | CTD | PMID:26377693 | bisphenol A | decreases expression | ISO | Cpne5 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of CPNE5 mRNA | CTD | PMID:25181051 more ... | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CPNE5 mRNA | CTD | PMID:32156529 | bisphenol A | increases expression | ISO | Cpne5 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of CPNE5 mRNA | CTD | PMID:34973380 | bisphenol F | decreases expression | EXP | | 6480464 | bisphenol F results in decreased expression of CPNE5 mRNA | CTD | PMID:30951980 | cadmium dichloride | decreases methylation | ISO | Cpne5 (Rattus norvegicus) | 6480464 | Cadmium Chloride results in decreased methylation of CPNE5 promoter | CTD | PMID:22457795 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | CPNE5 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to CPNE5 gene] | CTD | PMID:28238834 | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of CPNE5 mRNA | CTD | PMID:37019170 | chrysene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of CPNE5 mRNA | CTD | PMID:27858113 | doxorubicin | decreases expression | ISO | CPNE5 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of CPNE5 mRNA | CTD | PMID:29803840 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of CPNE5 mRNA | CTD | PMID:36227756 | ethanol | multiple interactions | EXP | | 6480464 | Ethanol affects the expression of and affects the splicing of CPNE5 mRNA | CTD | PMID:30319688 | gentamycin | decreases expression | ISO | Cpne5 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of CPNE5 mRNA | CTD | PMID:22061828 | hydroquinone O-beta-D-glucopyranoside | increases expression | ISO | CPNE5 (Homo sapiens) | 6480464 | Arbutin results in increased expression of CPNE5 mRNA | CTD | PMID:17103032 | kojic acid | increases expression | ISO | CPNE5 (Homo sapiens) | 6480464 | kojic acid results in increased expression of CPNE5 mRNA | CTD | PMID:16595896 | lead(0) | affects expression | ISO | CPNE5 (Homo sapiens) | 6480464 | Lead affects the expression of CPNE5 mRNA | CTD | PMID:28903495 | lipopolysaccharide | decreases expression | EXP | | 6480464 | Lipopolysaccharides results in decreased expression of CPNE5 mRNA | CTD | PMID:30942577 | maneb | multiple interactions | EXP | | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of CPNE5 mRNA | CTD | PMID:36117858 | methapyrilene | decreases methylation | ISO | CPNE5 (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of CPNE5 exon and Methapyrilene results in decreased methylation of CPNE5 intron | CTD | PMID:30157460 | methoxychlor | affects methylation | ISO | Cpne5 (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of CPNE5 gene | CTD | PMID:35440735 | para-Nitrosodiphenylamine | affects response to substance | ISO | CPNE5 (Homo sapiens) | 6480464 | CPNE5 gene SNP affects the susceptibility to 4-nitroso-N-phenylaniline | CTD | PMID:25622337 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of CPNE5 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | Cpne5 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of CPNE5 mRNA | CTD | PMID:33387578 | paracetamol | increases expression | ISO | CPNE5 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of CPNE5 mRNA | CTD | PMID:26690555 | paraquat | multiple interactions | EXP | | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of CPNE5 mRNA | CTD | PMID:36117858 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of CPNE5 mRNA | CTD | PMID:36331819 | pirinixic acid | multiple interactions | EXP | | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of CPNE5 mRNA | CTD | PMID:19710929 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of CPNE5 mRNA | CTD | PMID:18301758 | quartz | increases expression | ISO | Cpne5 (Rattus norvegicus) | 6480464 | Quartz results in increased expression of CPNE5 mRNA | CTD | PMID:32976597 | quartz | multiple interactions | ISO | Cpne5 (Rattus norvegicus) | 6480464 | Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of CPNE5 mRNA] | CTD | PMID:32976597 | resveratrol | multiple interactions | ISO | CPNE5 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of CPNE5 mRNA | CTD | PMID:23557933 | silicon dioxide | decreases expression | ISO | CPNE5 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of CPNE5 mRNA | CTD | PMID:25895662 | silicon dioxide | decreases expression | EXP | | 6480464 | Silicon Dioxide results in decreased expression of CPNE5 mRNA | CTD | PMID:29341224 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of CPNE5 mRNA | CTD | PMID:37682722 | sunitinib | decreases expression | ISO | CPNE5 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of CPNE5 mRNA | CTD | PMID:31533062 | tetraphene | increases expression | EXP | | 6480464 | benz(a)anthracene results in increased expression of CPNE5 mRNA | CTD | PMID:26377693 | tetraphene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of CPNE5 mRNA | CTD | PMID:27858113 | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of CPNE5 mRNA | CTD | PMID:21259345 more ... | trichloroethene | increases expression | ISO | Cpne5 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of CPNE5 mRNA | CTD | PMID:33387578 | trimellitic anhydride | increases expression | EXP | | 6480464 | trimellitic anhydride results in increased expression of CPNE5 mRNA | CTD | PMID:19042947 | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of CPNE5 mRNA | CTD | PMID:33045310 | valproic acid | increases methylation | ISO | CPNE5 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of CPNE5 gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | CPNE5 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of CPNE5 mRNA | CTD | PMID:37505509 | zidovudine | multiple interactions | ISO | CPNE5 (Homo sapiens) | 6480464 | [Zidovudine co-treated with IFNA1 protein] results in increased expression of CPNE5 mRNA | CTD | PMID:20370541 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene Ontology Annotations Click to see Annotation Detail View
Biological Process
Cellular Component
Molecular Function
Phenotype Annotations Click to see Annotation Detail View
Mammalian Phenotype
Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Biological Process
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Cellular Component
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Phenotype Annotations
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | MGDs mouse GO annotations | MGD data from the GO Consortium |
| 2. | Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. | Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73. |
| 3. | Mouse MP Annotation Import Pipeline | RGD automated import pipeline |
| 4. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:8889548 | PMID:9430674 | PMID:10349636 | PMID:11042159 | PMID:11076861 | PMID:11217851 | PMID:12477932 | PMID:14610273 | PMID:15489334 | PMID:16141072 | PMID:16141073 | PMID:18250453 |
| PMID:18614158 | PMID:18799693 | PMID:21873635 | PMID:24154525 | PMID:24194600 | PMID:27568519 | PMID:27626380 | PMID:28168849 | PMID:28634551 | PMID:31284824 | PMID:35951416 | PMID:37060937 |
Genomics
Comparative Map Data
| Cpne5 (Mus musculus - house mouse) |
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| CPNE5 (Homo sapiens - human) |
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| Cpne5 (Rattus norvegicus - Norway rat) |
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| Cpne5 (Chinchilla lanigera - long-tailed chinchilla) |
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| CPNE5 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| CPNE5 (Canis lupus familiaris - dog) |
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| Cpne5 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| CPNE5 (Sus scrofa - pig) |
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| CPNE5 (Chlorocebus sabaeus - green monkey) |
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| Cpne5 (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in Cpne5
3344 total Variants 
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