Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: SIM2 (SIM bHLH transcription factor 2) Homo sapiens
Symbol: SIM2
Name: SIM bHLH transcription factor 2
RGD ID: 1317540
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in negative regulation of transcription, DNA-templated and regulation of transcription by RNA polymerase II. Localizes to nuclear body.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bHLHe15; class E basic helix-loop-helix protein 15; HMC13F06; HMC29C01; MGC119447; SIM; single-minded family bHLH transcription factor 2; single-minded homolog 2; single-minded homolog 2, short isoform; transcription factor SIM2
Mus musculus (house mouse) : Sim2 (single-minded family bHLH transcription factor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sim2 (SIM bHLH transcription factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sim2 (SIM bHLH transcription factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SIM2 (SIM bHLH transcription factor 2)
Canis lupus familiaris (dog) : SIM2 (SIM bHLH transcription factor 2)
Sus scrofa (pig) : SIM2 (SIM bHLH transcription factor 2)
Chlorocebus sabaeus (African green monkey) : SIM2 (SIM bHLH transcription factor 2)
Heterocephalus glaber (naked mole-rat) : Sim2 (SIM bHLH transcription factor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2136,699,115 - 36,749,917 (+)EnsemblGRCh38hg38GRCh38
GRCh382136,699,115 - 36,750,219 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372138,071,991 - 38,122,510 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362136,993,861 - 37,044,088 (+)NCBINCBI36hg18NCBI36
Build 342136,993,860 - 37,040,483NCBI
Celera2123,270,361 - 23,320,891 (+)NCBI
Cytogenetic Map21q22.13ENTREZGENE
HuRef2123,547,929 - 23,598,327 (+)NCBIHuRef
CHM1_12137,632,637 - 37,683,392 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SIM2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1317540
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.